Inter Milan vs Liverpool Odds & Prediction – Champions League Round of 16 Leg 1

By John Dillon in Soccer News
Updated: October 27, 2022 at 4:03 am EDTPublished:

- Anfield’s six-time winners of trophy head to Italy’s San Siro at 3:00 pm ET on Wednesday
- Inter has slipped from the top spot in Serie A while Liverpool has four straight EPL wins
- See all the odds & best bets for Inter Milan vs Liverpool in the Champions League Round of 16 Leg 1
Inter Milan will look to escape from a slump in domestic form when it hosts Liverpool in the Champions League last 16 on Wednesday.
In Italy’s Serie A, Inter has been knocked off top perch after markedly winning just one of its last four games.
Meanwhile, Liverpool is enjoying a run of four straight wins as it sits second in England’s Premier League.
Inter Milan vs Liverpool Odds
Matchup | Spread | Moneyline | Total |
---|---|---|---|
Inter Milan vs Liverpool | INT +0.5 (-120) | LIV -0.5 (+100) | INT +265 | LIV +102 | DRAW +265 | Ov 2.5 (-152) | Un 2.5 (+123) |
Odds as of February 15 at Barstool
It is the English team that is clearly favored in these odds, although the margin of victory may not be too wide.
Furthermore, Liverpool won its group before Christmas with a 100-percent record.
Concurrently, Inter finished second in its section behind Real Madrid.
Klopp Lifted Trophy in 2019
Jurgen Klopp’s Anfield team was a finalist in the competition in 2018 and the winner the following season.
Simone Inzaghi’s Inter outfit, contrarily, is in the knockout stage for the first time in a decade.

Therefore, the oddsmakers at Barstool Sportsbook favor Liverpool for an away win in northern Italy at +102 in the Champions League odds.
Barstool further rates inter at +265 for a home win – with the draw also at +265.
The first leg tie kicks off at San Siro at 3:00 pm ET.
Liverpool won all six games in a tough group.
After its excellent performance in the group stage, Liverpool is one of the most powerful teams in the competition.
It won all six games in a tough group which also included Atletico Madrid, AC Milan, and Porto.
🎙️ | #INTERPODCAST @RichHall80 and Thomas Lawrence look back on the games against Roma and Napoli, as well as looking ahead to the Champions League test against Liverpool 🏟️
Listen now 👉 https://t.co/9ibGtklF6c@GentlemanUltra #ForzaInter pic.twitter.com/AwfCxk1tUZ
— Inter ⭐⭐ (@Inter_en) February 15, 2022
There were two stand-out wins – by 5-1 at Porto and by 3-2 in Madrid.
Although Liverpool is nine points behind the EPL leader Manchester City, it has a game in hand – and has yet to visit City.
So its hopes of catching up in the title race are not completely extinguished.
Only Two Defeats for Reds
Meanwhile, Inter will be confronted by the daunting fact that Liverpool has lost only twice in a busy season.
Those were both EPL defeats – with the team set to appear in the EFL Carabao Cup final against Chelsea at Wembley on February 27.

It has also reached the Fifth Round of the FA Cup.
Last time out it was a 1-0 winner at Burnley last Sunday in the EPL.
The winner was scored by Brazilian midfielder Fabinho – his third goal in four league games.
One of those came from the penalty spot.
However, Fabinho is still in the kind of form which makes odds of +1700 for him to get on the scoresheet against Inter look very attractive.
Inter Milan vs Liverpool Statistics
3 | Wins | 6 |
1 | Draws | 0 |
2 | Losses | 0 |
8 | Goals | 17 |
0 | Goals Against | 6 |
7 | Yellow Cards | 8 |
1 | Red Cards | 0 |
2 | Clean Sheets | 2 |
*Stats from UCL 2021-22 Group Stage.
In Italy, meanwhile, Inter’s sudden dip has seen it lose first place after being top for eight rounds of fixtures.
It suffered a 2-1 defeat by rivals AC Milan and then was then further held to a 1-1 draw at Napoli last weekend.
Inter Helped By Facing Moldovan Minnows
During the UCL group stage, it was significantly helped by wins at home and away against small Moldovan club Sherriff Tiraspol.
There were, furthermore, two defeats by group winners Real Madrid.
https://youtu.be/uNwsQJkJjWM
Meanwhile, it defeated Shakhtar Donetsk 2-0 and drew 0-0 in Ukraine.
This is not the kind of European form that will be of major concern to the six-time winners Liverpool.
Inter, however, will be given some confidence by its excellent home form.
Alexis Sanchez ready for tough Liverpool challenge in Champions League after coming into form for Inter Milan and Chilehttps://t.co/19HVLEvw5E
— The Sun Football ⚽ (@TheSunFootball) February 15, 2022
There have been only three defeats in the last 30 home matches across all competitions for Inter.
Liverpool, though, will be boosted by the fact that it has already won at San Siro this season.
Inter has won only once in four meetings with English clubs at this stage.
There was a 2-1 win in the final group game last December – with Liverpool’s goals scored by Mo Salah and Divock Origi.
Undoubtedly, Inter’s recent inconsistent patch has come as a surprise. Previously, the team had been on a 13-game run of 11 league wins and two draws.
𝙄𝙣𝙨𝙞𝙙𝙚 𝘽𝙪𝙧𝙣𝙡𝙚𝙮 is here 🤩
Get a unique view of our 1-0 victory at Turf Moor, thanks to another goal from @_fabinhotavares 🇧🇷🔴
— Liverpool FC (@LFC) February 15, 2022
Even now, it has lost only once in its last 11 games in all competitions – with eight wins and two draws.
However, it has won only once in four meetings with English clubs at this stage of the competition.
One of those setbacks came in the most recent collision between these sides in 2007/08.
EPL Giants Won Twice In 2008
Liverpool was a 2-0 winner at Anfield back then before claiming a 1-0 win in Italy.
To sum up, Inter’s good home form means it could comfortably claim a draw – and the odds are good at +265.
But Fabinho has been consistently effective lately and is rated at a very good, wide price to get among the goals for the visitors.
Pick: Fabinho to score (+1700)
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Sports Writer
John Dillon is a leading member of the UK's sporting media, having spent three decades as a national newspaper soccer and sports writer, broadcaster and author. He has covered five World Cups, six European Championships and was Chief Sports Writer at the Daily Express for 14 years.