FIU vs Penn State Betting Line, Prediction & How to Watch

• No.2 Penn State looks for its second win of the season
• Heisman contender Drew Allar welcomes the FIU Golden Panthers to town
• Read below for my FIU vs Penn State prediction, as well as the betting line

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Week 2 of the college football season proceeds with the FIU Golden Panthers heading to State College to face the Penn State Nittany Lions. FIU (1-0) and No.2 Penn State (1-0) play at noon ET on Saturday, September 6th, on a Big Ten Network broadcast.

I’ve made my FIU vs Penn State prediction for Saturday and handed out the betting line as kickoff approaches

FIU vs Penn State Prediction

• Pick: Penn State -41.5 (-110 at MGM)

Penn State comes into 2025 with massive expectations as the preseason No.2 team in the country. They opened the season with a 35-point blowout over Nevada.

Quarterback Drew Allar had an efficient game, throwing for 217 yards and a touchdown while both of Penn State’s stud running backs – Kaytron Allen and Nicholas Singleton – found the end zone. Syracuse transfer Trebor Pena and USC transfer Kyron Ware-Hudson combined for 13 catches for 163 yards and a touchdown.

Defensively, Penn State is arguably more talented. Dani Dennis-Sutton opened the season with a sack and 2.5 tackles for loss, forcing two fumbles. AJ Harris and Zakee Wheatley anchor a top secondary. Even defensive tackle Zane Durant got in on the action, picking off a pass last week.

FIU also enters 1-0, clobbering Bethune-Cookman 42-9 last week. The Golden Panthers had a balanced attack, throwing for 233 yards and running for 223 yards. They scored six rushing touchdowns, including a pair from quarterback Keyone Jenkins. FIU is looking to win more than four games for the first time since 2019.

With this in mind, back Penn State to blow out FIU and make a case to be No.1 in the country come next week. Look for Allar to have an efficient game with healthy counting numbers to boost his Heisman candidacy. Allar is between +1600 and +2000 in Heisman odds. If you want to bet on Allar, take him +2000 at DraftKings.

FIU vs Penn State Betting Lines

The oddsmakers have Penn State as a home favorite with the total ranging from 53.5 to 54. Over bettors should take over 53.5 at DraftKings with -110 odds. Under bettors should take the Caesars total of under 54 at -110 odds.

If you are backing Penn State, you can get them -41.5 on the spread at -110 on BetMGM. If you are betting on FIU, take them +42.5 on DraftKings at -123.

Odds as of September 5, 2025, at top-rated CFB betting apps. Get in on the Week 2 action with the top sportsbook promos.

Previous Matchups

Penn State has hosted FIU once previously, a 59-point beatdown to open the 2007 season. Penn State featured a dynamic linebacker room with future NFL players Dan Connor, Sean Lee, and Navorro Bowman.

Legendary Penn State coach Joe Paterno was in his 42nd of 46 seasons at State College. FIU, meanwhile, was in its first year under now-Miami head coach Mario Cristobal.