UFC 320 Predictions, Picks, Props & Latest Odds – Ankalaev vs Pereira 2

• Saturday’s UFC 320 is headlined by the light heavyweight title rematch between Magomed Ankalaev and Alex Pereira
• Ankalaev already defeated Pereira via decision in their March meeting
• Check out my UFC 320 predictions for Ankalaev vs Pereira 2 and more

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Saturday’s UFC 320 is an absolute monster of a card from T-Mobile Arena in Las Vegas. Two title fights anchor a 14-fight lineup, with Magomed Ankalaev defending his light heavyweight belt against former champion Alex Pereira in the main event. Online sportsbooks are split on this rematch, with Ankalaev checking in at -250 while Pereira sits at +200. That’s where I see value, but not necessarily on the moneylines.

Saturday’s card kicks off early from Vegas with early prelims starting at 6 PM ET on UFC Fight Pass, prelims at 8 PM ET on ESPN, and the main card dropping at 10 PM ET on ESPN+ PPV.

Here are my UFC 320 picks for the fights that matter most on this stacked card.

Jump to Fight Predictions: Ankalaev vs Pereira 2 | Dvalishvili vs Sandhagen | Prochazka vs Rountree | Pyfer vs Magomedov | Mix vs Wiklacz | Soriano vs Veretennikov | Emmett vs Zalal

Ankalaev vs Pereira 2 Prediction

Let’s address the elephant in the room: Ankalaev already beat Pereira convincingly just seven months ago. He did it without landing a single takedown, going 0-for-11 on his attempts. That’s actually the worst-case scenario for the Russian champion, and he still cruised to a decision win by outstriking the supposed striking specialist.

For this rematch, Pereira needs to show something different. The 38-year-old Brazilian looked flat in their first meeting, whether from travel fatigue or simply being outclassed. His legendary left hook never found its mark, and Ankalaev’s southpaw stance completely neutralized Pereira’s devastating calf kicks.

Tale of the Tape

The age factor can’t be ignored here. Ankalaev is entering his prime at 32, while Pereira is pushing 40 and has absorbed serious damage throughout his kickboxing and MMA careers. Speed kills at light heavyweight, and Ankalaev has the clear edge in reaction time and foot speed.

More importantly, Ankalaev fights with his chin tucked and rarely overextends. He’s content to bank rounds with safe kicks and clinch control rather than chase a highlight reel. That’s kryptonite for a counter-striker like Pereira who needs opponents to walk into his power shots.

The wildcard is whether Ankalaev actually pursues takedowns this time. His sambo credentials are world-class, and if he mixes in wrestling early, it could sap Pereira’s explosiveness for the later rounds. But honestly, he might not need to. The stand-up game alone favored him last time, and there’s no reason to think that changes now.

• UFC 320 Pick: Ankalaev by Decision (+145 at Caesars)

Dvalishvili vs Sandhagen Prediction

The co-main event features another championship bout, with Merab Dvalishvili defending his bantamweight title against Cory Sandhagen. The UFC 320 odds tell the story here: Dvalishvili opened at -350 and has been bet up to -450, while Sandhagen sits at +325.

Dvalishvili’s cardio is the stuff of legend. The Georgian wrestler averages 5.84 takedowns per 15 minutes and simply never stops coming forward. He’s added wrinkles to his game lately too, scoring his first UFC submission against Sean O’Malley in their rematch. That’s a scary development for the division.

Tale of the Tape

Sandhagen brings elite striking and sneaky submissions from his back, but he’s fighting uphill against the relentless pressure. His 62% takedown defense won’t hold up over five rounds against Dvalishvili’s volume shooting. Once the Georgian gets on top, he’s virtually impossible to shake off.

The path to victory for Sandhagen involves maintaining distance, landing clean counters, and making Dvalishvili pay for his entries. Problem is, nobody has successfully implemented that gameplan over 25 minutes. Dvalishvili’s chin is granite, and his cardio means he’ll be shooting doubles in round five with the same explosiveness as round one.

• Dvalishvili vs Sandhagen Pick: Fight Goes the Distance (-330 at FanDuel)

Prochazka vs Rountree Prediction

This light heavyweight clash between Jiri Prochazka and Khalil Rountree should produce fireworks. Prochazka opened as a -180 favorite and has been bet up to -200, while Rountree sits at +165.

Here’s what makes this matchup compelling: Rountree thrives in technical striking battles where he can establish his Muay Thai rhythm. His calf kicks are devastating, and he’s shown improved patience in recent fights. But Prochazka doesn’t fight technical battles. He drags you into chaos, and historically, Rountree wilts when fights get messy.

My all time favourite Jiri Prochazka video#UFC320 pic.twitter.com/e1KQLFFWfM

— 𝗫𝗮𝘃𝗲 🇦🇺 (@WonderbreadMMA) October 4, 2025

Prochazka’s chin has held up against harder hitters than Rountree. He ate bombs from Jamahal Hill and kept marching forward. Meanwhile, Rountree tends to score flash knockdowns without finishing power at 205. When he can’t get opponents out of there early, he tends to fade.

The Czech samurai’s relentless pressure and unorthodox angles should overwhelm Rountree as the fight progresses. I see this ending violently in the middle rounds.

• UFC 320 Prediction: Prochazka by KO/TKO (-110 at BetMGM)

Pyfer vs Magomedov Prediction

Opening the main card, Joe Pyfer takes on Abus Magomedov in a middleweight scrap with serious implications. Pyfer checks in as a -250 favorite, with Magomedov at +200.

Magomedov has some of the worst cardio in the UFC. He’s explosive for about five minutes, throwing flashy kicks and heavy combinations. After that? He’s basically a sitting duck, shooting desperate takedowns and gasping for air.

Show some love for Germany’s Own ❤️ 👊 #UFC320

🇩🇪 Abus Magomedov vs Joe Pyfer 🇺🇸 pic.twitter.com/k5OutK1EFY

— UFC Europe (@UFCEurope) October 4, 2025

Pyfer is the opposite: smart, composed, and gets stronger as fights wear on. He showed maturity in grinding out Kelvin Gastelum, proving he doesn’t need the knockout to win. But against Magomedov, the finish will be there for the taking.

Once Magomedov starts fading (usually around the 7-minute mark), Pyfer’s pressure and power shots will find their mark. This has late stoppage written all over it.

• Pyfer vs Magomedov Pick: Pyfer to Win by Any Knockout, Submission or DQ (-115 at DraftKings)

Mix vs Wiklacz Prediction

Former Bellator champion Patchy Mix looks to bounce back from a flat UFC debut when he faces debuting Jakub Wiklacz. Mix is a -325 favorite, with the Polish fighter at +260.

Mix looked terrible against Mario Bautista, but context matters. Bautista is a legitimate top-15 guy, while Wiklacz is making his UFC debut on short notice. That’s a massive step down in competition, and Mix knows it.

What makes this interesting is both fighters are submission specialists. Mix has 13 submission wins, primarily guillotines, while Wiklacz has 10 of his own. When two grapplers collide, it often comes down to who’s more composed under pressure. That’s where Mix’s experience edge matters.

I expect Mix to make a statement here, catching a guillotine when Wiklacz shoots a panicked takedown. Sometimes fighters need a confidence-builder, and this is the perfect spot for it.

• Mix vs Wiklacz Pick: Mix by Submission (+175 at MGM)

Soriano vs Veretennikov Prediction

Punahele Soriano continues his welterweight resurgence against Nikolay Veretennikov on the prelims. The Hawaiian is a heavy -325 favorite against Veretennikov at +260.

Since moving down to 170 pounds, Soriano looks like a different fighter. He’s not getting outsized anymore, and his explosiveness translates into devastating power. That 31-second knockout of Uros Medic wasn’t a fluke. It’s what happens when Soriano fights guys his own size.

Veretennikov is technically sound but doesn’t have the defensive wrestling to keep this standing. Once Soriano starts mixing level changes with his overhand rights, openings will appear. The Kazakh fighter’s high guard also leaves him vulnerable to body shots, which Soriano loves throwing.

• Soriano vs Veretennikov Pick: Soriano by KO/TKO (-120)

Emmett vs Zalal Prediction

This featherweight bout pits power against precision. Josh Emmett brings one-punch knockout power but sits as a sizeable +360 underdog against the surging Youssef Zalal at -500.

Emmett has become predictable at this stage of his career. He loads up on overhands and hopes one lands clean. Against a mover like Zalal who just schooled Calvin Kattar, that’s a tough sell. Zalal’s footwork, head movement, and ability to change levels will frustrate the aging power puncher.

The 40-year-old Emmett is tough as nails and rarely gets finished, but Zalal doesn’t need the stoppage. He’ll pick Emmett apart from range, mix in takedowns when needed, and cruise to a decision. Father Time remains undefeated, and this feels like another passing of the torch at featherweight.

• UFC 320 Picks: Zalal by Decision (-180)

UFC 320 Odds – Full Card

Main Card

Prelims

Early Prelims

Odds as of October 3rd at BetMGM. Check out the best UFC betting apps for UFC 320 on Saturday.

In terms of the UFC 320 odds movement, the biggest shift has been on Dvalishvili. The champion opened at -350 and has been hammered up to -450. That’s too rich for my blood on a straight play, but the fight going the distance at -360 offers better value. Dvalishvili rarely finishes, and Sandhagen is too tough to get stopped.

Meanwhile, I’m seeing sharp money on the Ankalaev decision prop. The moneyline sits at -250, but getting him by decision at +140 is the smarter angle. Pereira’s never been knocked out at light heavyweight, and Ankalaev isn’t exactly a finishing machine. He’s a point-fighter who happens to be really good at it.

The underdog I’m most interested in? Keep an eye on Jakub Wiklacz at +260. Mix looked awful in his UFC debut, and Wiklacz is a legit grappling threat making his debut in front of a home crowd. Sometimes that energy matters. But I’m not pulling the trigger on that one. Mix by submission feels like the safer play given his experience edge.

Best Bets Recap for UFC 320

When the dust settles on Saturday night, I expect the champions to retain their belts, but the prop bets offer the real value. My top UFC predictions for the card:

• Ankalaev by Decision (+145)
• Prochazka by KO/TKO (-110)
• Pyfer Inside the Distance (-115)
• Mix by Submission (+175)
• Soriano by KO/TKO (-120)

Those UFC picks give us a mix of favorites and value props without laying massive chalk. Remember, sometimes the best bet is the one that captures how a fight ends, not just who wins. That’s especially true on a card like UFC 320 where several heavy favorites are priced out of straight betting range.