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Oregon vs Washington Prediction, Picks & Odds: Big Ten Rivalry Betting Guide

Brady Trettenero

By Brady Trettenero in College Football

Published:


Nov 22, 2025; Eugene, Oregon, USA; Oregon Ducks quarterback Dante Moore (5) celebrates after scoring a touchdown against the Southern California Trojans during the second half at Autzen Stadium. Mandatory Credit: Troy Wayrynen-Imagn Images
  • Oregon is a 7-point road favorite over Washington in the 118th edition of this Pacific Northwest rivalry
  • The Ducks average 228.6 rushing yards per game (10th nationally) and boast an 11-game road winning streak
  • Check out the Oregon vs Washington prediction, odds, and spread, below

The Oregon Ducks will look to keep their College Football Playoff dreams alive Saturday when they visit the Washington Huskies in the 118th edition of this storied Pacific Northwest rivalry. Fox has the coverage starting at 3:30 p.m. ET.

With Oregon built for big moments and Washington thriving at home, my Oregon vs Washington prediction expects a close battle on Black Friday weekend.

Here are my college football picks for Saturday, November 29.

Oregon Ducks vs Washington Huskies Prediction, Picks

  • Oregon vs Washington Pick: Over 51.5 (-110)

Sports Betting Dime •

Pick
Odds
Over +51.5
Over/Under
CFB • Oregon Ducks @ Washington Huskies
-110 on FanDuel
SCHEDULED • 11/29/2025
Tally (Win %)
0-0-0 (0%)
Money Meter
$0.00
ROI
0.0%
Betslip #1764442900331-481c-459

My Oregon at Washington best bet is on the Over. Both offenses rank in the top 20 nationally in points per game, with Oregon averaging 39.27 (8th) and Washington putting up 35.55 (18th).

Washington’s 91.67% red zone efficiency ranks 19th nationally and tops Oregon’s 88.89% mark. The Huskies cash in with touchdowns when they get inside the 20, especially at home where they’ve won 25 of their last 26 games. That home-field advantage has been critical in close games.

Oregon’s balanced attack creates problems for defenses trying to key on one dimension. The Ducks average 228.6 rushing yards per game (10th nationally) while Dante Moore completes 72.64% of his passes (5th nationally). They’ve posted 28 games with 250+ passing and 150+ rushing yards since 2022, most in the FBS.

Offensive StatsOregon DucksWashington Huskies
Points Per Game39.27 (8th)35.55 (18th)
Total Yards Per Game471.8 (11th)427.5 (29th)
Rushing Yards Per Game228.6 (10th)171.1 (57th)
Passing Yards Per Game243.2 (53rd)256.5 (37th)
Third Down %50.0% (23rd)51.9% (18th)
Red Zone Efficiency88.89% (36th)91.67% (19th)

The numbers show two offenses built differently but equally capable of putting up points. Oregon pounds the rock while Washington leans on the pass, but both convert at elite rates and should score freely. Neither defense has been dominant enough to slow down these high-powered attacks.

The trends support the Over. Washington is 4-0 to the Over in their last four home games against teams with winning road records. Oregon is 4-0 to the Over in their last four games after allowing less than 100 rushing yards. Both teams also rank in the top 25 nationally in third-down conversion percentage, which means sustained drives that keep the clock moving and end in points rather than punts.

Same-game parlay worth a look

Dante Moore has been exceptional under pressure, completing 72.64% of his passes (5th nationally). With Oregon’s receiver room banged up, expect the Ducks to lean heavily on freshman Jordan Davison, who has 13 rushing touchdowns in just 79 carries (third most by an Oregon freshman all-time). He’s become their most reliable weapon in short-yardage situations.

Demond Williams Jr. has rushed for 568 yards and six touchdowns while posting a 171-game home streak without an interception. He’s most dangerous in the fourth quarter when Washington does its best work, making him a strong play for over rushing yards.

  • Over 51.5
  • Jordan Davison anytime touchdown
  • Demond Williams Jr. Over rushing yards

Oregon vs Washington game predictions

Oregon vs Washington moneyline prediction

I’m riding with Oregon. The Ducks have won 16 of their last 21 meetings with Washington and are 8-2 ATS in their last 10 trips to Seattle. Their 11-game road winning streak is the longest in the FBS, and Dan Lanning has built a program that thrives in hostile environments.

Oregon vs Washington spread prediction

I’m leaning Washington. The Huskies are 5-0 ATS in their last five games after allowing less than 275 total yards, and they held opponents to just 226.3 yards per game over their last three contests. That defensive improvement has coincided with better offensive execution.

Oregon struggles in the fourth quarter with a minus-16 scoring differential (104th nationally), while Washington ranks third in the nation at plus-70. That’s a massive gap when games are decided late, and rivalry games typically come down to the final minutes.

The line movement from 11.5 to 7 shows sharp money backing the Huskies getting double digits at home. Washington has the home crowd, the motivation, and the fourth-quarter execution to keep this within a touchdown.

Oregon vs Washington Over/Under prediction

I’m taking the Over. Both teams rank in the top 25 nationally in third-down conversion percentage, with Washington at 51.9% (18th) and Oregon at 50.0% (23rd). Washington averages 10.45 points in the fourth quarter (4th nationally), while Oregon scores in bunches early.

Oregon vs Washington odds

  • Spread: Oregon -7 (-110) | Washington +7 (-110)
  • Moneyline: Oregon -275 | Washington +225
  • Over/Under: Over 51.5 (-110) | Under 51.5 (-110)

Odds via Caesars Sportsbook. Check out the best Caesars Sportsbook promos before betting on Week 14 college football.

Oregon vs Washington Key Betting Trend

Oregon is 16-4-1 ATS in its last 21 meetings with Washington. Find more college football betting trends for Oregon vs Washington.

How to watch Oregon vs Washington

LocationAlaska Airlines Field at Husky Stadium, Seattle, WA
DateSaturday, November 29, 2025
Kickoff3:30 p.m. ET
TVFox

Oregon vs Washington latest injuries

Oregon: WR Gary Bryant Jr. (ankle), RB Jayden Limar (undisclosed), WR Jeremiah McClellan (shoulder), WR Dakorien Moore (knee) all questionable. WR Evan Stewart (knee) out for season.

Washington: WR Denzel Boston (knee), WR Raiden Vines-Bright (undisclosed), WR Justice Williams (undisclosed) all questionable.

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Brady Trettenero
Brady Trettenero

Lead NHL & NCAAF Editor

Brady is the lead NHL and College Football editor at Sports Betting Dime, where he specializes in betting odds and data-driven analysis. Brady has over 10 years experience working in sports media, with work published by outlets such as ESPN, CBS Sports, Yahoo! Sports and Fox Sports.

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