Brewers vs Cardinals Expert Picks & Betting Splits (May 6)

• Milwaukee vs St. Louis was rained out Tuesday
• Oddsmakers have made Wednesday’s game a virtual toss-up
• See our detailed analysis and best bets for Brewers at Cardinals today

The Brewers and Cardinals were rained out Tuesday night. They’re scheduled to get back at it today at Busch Stadium. First pitch is set for 1:15 pm, ET. You can watch on MLB.TV, which is included in each Fubo TV subscription.

St. Louis won the opening game of the series 6-3 on Monday. (Tuesday’s rained out game will be made up as part of a split doubleheader on July 7.)

Today, Cardinals righty Andre Pallante (3-2, 3.73 ERA) will go against Milwaukee rookie righty Brandon Sproat (0-2, 6.75). Sproat has never faced the Cardinals.

Oddmakers have made today’s game a toss-up.

We’ll break down the key metrics, trends and stats and find the best bets for Brewers at Cardinals on Wednesday afternoon.

Brewers vs Cardinals Odds

The graphic above shows the best available odds, which are subject to change

The matchup opened with a nearly even moneyline, slightly favoring the visiting Brewers at -110 while pricing the home Cardinals at -106. The implied probability of these opening lines equates to roughly 52.4% for Milwaukee and 51.5% for St. Louis (vig included). The opening runline offered Milwaukee at -1.5 (+155) and St. Louis at +1.5 (-188).

While the total has remained flat at 8.5 runs since opening, the underlying juice has shifted. The Over originally opened at even money (+100) but has since moved to -107 at most major sportsbooks. This line movement is directly supported by overwhelming betting volume anticipating a high-scoring affair.

Cardinals vs. Brewers Predictions & MLB Best Bets

Moneyline Prediction: Cardinals (-105 at BetMGM)

St. Louis enters with a clear edge on the mound. Andre Pallante has been reliable with a 3.73 ERA, a 1.31 WHIP, and 7.47 strikeouts per nine innings. The Brewers are relying on Brandon Sproat (6.75 ERA and a 1.61 WHIP over 26.2 innings) who is allowing opponents to bat .286.

St. Louis is 7-3 over its past 10 games. We’re backing the home team Cardinals on the moneyline because that provides the highest win probability.

Over/Under Prediction: Over 8.5 Runs (+100 at BetMGM) With Sproat surrendering 2.36 home runs per nine innings, the St. Louis offense is in a highly favorable spot. The Cardinals hold a .730 team OPS and average 1.26 home runs per game at Busch Stadium. Although the Over has cashed in just 30% of Milwaukee’s last 10 games, the specific pitching matchup today points toward offensive success for the home team. We expect St. Louis to carry the scoring burden and push the total past 8.5 runs.

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Best Player Prop Bet: Jordan Walker Over 1.5 Total Bases (+111 at DraftKings) Right fielder Jordan Walker has been highly productive in the batter’s box, posting a .308 batting average, a .585 slugging percentage, and a .961 OPS. With 10 home runs on the season, Walker draws a favorable matchup against Sproat, who struggles to keep the ball in the park. Taking Walker to record at least two total bases at plus-money odds is the sharpest prop angle available.

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Brewers vs Cardinals Situational Team Betting Trends

• Cardinals as a Favorite: St. Louis has won 66.7% of their games when listed as the betting favorite this season (2-1).
• Cardinals as an Underdog: St. Louis boasts a 60.7% win rate when playing as an underdog (17-11).
• Cardinals Recent Form: Over their last 10 games, St. Louis has played to a 70.0% win percentage (7-3).
• Brewers Recent Underdog Performance: Milwaukee has a 0.0% win rate as an underdog over their last 10 games (0-1).

Andre Pallante vs Brandon Sproat 2026 Stats

Andre Pallante vs Brewers

Brewers Hitters vs Andre Pallante

Cardinals vs Brewers Home/Road Team Statistics

The offensive statistics below reflect St. Louis’s performance in home games and Milwaukee’s performance in away games to provide accurate situational context.

Brewers vs Cardinals Public Betting Splits & Market Action

Let’s dive into MLB public betting trends for today’s game in St. Louis:

The moneyline market reveals a mild divergence between the ticket count and the overall money. St. Louis is drawing the majority of the tickets at 56.2%, indicating casual support for the home team. However, the money leans slightly in the opposite direction, with 53.9% of the overall stake placed on Milwaukee. Because neither opposing side reaches the required 60% threshold, this does not qualify as a true sharp versus public scenario.

Unlike the moneyline, the runline market shows absolute consensus. Bettors are enthusiastically taking the runs with the Cardinals, accounting for 76.0% of the tickets and a staggering 90.7% of the total stake. Action on the game total is equally decisive. The Over is dominating the market, holding 77.3% of the betting slips and an overwhelming 81.4% of the total money wagered, aligning perfectly with our prediction to back the Over.

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