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Picks, Predictions & Splits for Brewers vs Padres

Michael Harrison

By Michael Harrison in MLB Baseball

Published:


Cooper Pratt high fives second baseman Brice Turang
Jul 20, 2026; Milwaukee, Wisconsin, USA; Milwaukee Brewers shortstop Cooper Pratt (12) high fives second baseman Brice Turang (2) following the game against the New York Mets at American Family Field. Mandatory Credit: Jeff Hanisch-Imagn Images
  • The Brewers and Padres open up a three-game set in San Diego beginning Monday evening
  • Logan Henderson will toe the rubber, up against newly acquired Casey Mize for the Padres
  • See the odds and analysis for two National League squads that both could be playoff bound

The Brewers (74-44) open a series against the Padres (62-57) at Petco Park Monday night. First pitch is scheduled for 6:40 PM PT / 9:40 PM ET with broadcast coverage on SDPA and BREW.

The Brew Crew have won five of six, and comfortably sit atop the NL Central standings by 5.5 games over the Cubs. Their adversaries have taken three of four, and find themselves a game out of the final Wild Card spot in the National League. Keep reading for my predictions and picks for this duel, that sees Milwaukee as the favorites in the MLB odds.

Brewers vs Padres Predictions & Best Bets

  • The Pick: Brewers Moneyline (-107 at Caesars)
  • Player Prop Pick: Logan Henderson Over 5.5 Strikeouts (+118 at Caesars)

I am backing the road team in this contest. Milwaukee boasts a distinct advantage on the mound with Logan Henderson, who owns a 2.70 ERA and a 0.90 WHIP over 50.0 innings. San Diego counters with Casey Mize, who coughed up eight runs in his Padres debut, after being acquired at the trade deadline from the Tigers.

The Brewers have been elite all season, holding a 62.7% win rate overall and winning seven of their last ten outings. You can find the Milwaukee Moneyline at -107 at Caesars, but there is also value looking at alternative markets. Kalshi prices a Milwaukee victory at 55¢ for “Yes”, providing a unique payout structure.

For player props, I am targeting Logan Henderson Over 5.5 Strikeouts (+118 at Caesars). He averages 11.16 K/9 and faces a lineup seeing his arsenal for the first time.

Three straight outings he’s blown over that total, with an average of eight punchouts in those contests.

Starting Pitcher Matchup & Batter vs Pitcher Data

Casey Mize vs Logan Henderson

Milwaukee sends a burgeoning ace to the hill, while San Diego hands the ball to a starter searching for answers after a porous team debut. Henderson has been a stabilizing force, compiling a 6-1 record alongside his stellar 2.70 ERA. His 3.09 FIP indicates this success is sustainable.

Mize endured a rough first start for San Diego. He surrendered eight earned runs in 3.1 innings of work, allowing three free passes and a home run. For the campaign, his numbers look much better.

StatisticCasey Mize (SD)Logan Henderson (MIL)
Win-Loss Record4-76-1
ERA3.402.70
WHIP1.090.90

I will compare the road offensive metrics for Milwaukee against the home offensive metrics for San Diego to highlight the situational environment.

StatisticBrewers (Rank)Padres (Rank)
Win Percentage.627 [1st].521 [11th]
Runs per Game4.80 [5th]*3.85 [27th]*
Batting Average.249 [5th]*.230 [27th]*
OPS.712 [14th]*.672 [28th]*
Average Exit Velocity88.5 [11th]*88.1 [15th]*
Stolen Bases per Game1.00 [3rd]*1.07 [4th]*
Team ERA3.47 [2nd]4.17 [17th]
Pitching WHIP1.16 [2nd]1.32 [17th]
Pitcher K/99.86 [2nd]8.24 [21st]

Betting Odds, Splits & Injury Updates

Bet TypeBrewersPadres
Moneyline-107-103
Runline-1.5 (+158)+1.5 (-190)
Total RunsOver 7.5 (+100)Under 7.5 (-120)

Odds as of August 10 from Caesars.

Looking at MLB public betting splits, the ticket distribution slightly favors the Padres (+1.5) at 53.0%. However, an overwhelming 91.8% of the runline handle backs the Brewers. This massive discrepancy shows larger wagers are aggressively targeting the road favorites to win by multiple runs.

On the total, both tickets (69.3%) and money (63.4%) heavily support the Over. Bettors anticipate the Brewers exploiting Mize’s control issues that he dispalyed in his Padres debut.

Injury Report

TeamPlayer NamePositionInjuryStatus
MILJoey OrtizSSNeckQuestionable
MILSal FrelickOFShoulder10-Day IL
MILKyle HarrisonSPCalfQuestionable
MILBrandon WoodruffSPShoulder60-Day IL
SDMiguel AndujarDHWrist10-Day IL
SDRamón LaureanoOFHip60-Day IL
SDJoe MusgroveSPElbow60-Day IL
SDLucas GiolitoSPElbow15-Day IL

How to Watch Brewers vs Padres

TV Networks: Brewers.TV & Padres.TV

Away Team: Milwaukee Brewers

Home Team: San Diego Padres

Date: Monday, August 10th

Game Time: 6:40 PM PT / 9:40 PM ET

Venue: Petco Park

Location: San Diego, California

Michael Harrison
Michael Harrison

Sports & Entertainment Writer

Michael "Hound Dog" Harrison is well known in the sports industry as the resident statistician for the SC with Jay Onrait Show. He has worked at TSN for over 20 years, is the CEO of his "All Bets Par Off" weekly golf betting videos and his HDOG POD, along with several others.

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