Astros vs Twins Predictions & Props to Target on May 20

• The Twins are -146 moneyline favorites this afternoon versus the Astros
• Minnesota starter Joe Ryan brings a 3.20 ERA and 1.01 WHIP into action
• Don’t miss the top Astros vs Twins predictions and props to target on May 20, below

The Houston Astros (19-30) and Minnesota Twins (22-26) wrap up their three-game series this afternoon at Target Field, with first pitch scheduled for 1:40 PM ET.

The Twins are looking to bounce back after the Astros secured a 2-1 victory last night, fueled by an Isaac Paredes home run. Online sportsbooks like their chances, pegging Minnesota as favorites in the MLB odds.

A big reason why bookmakers are so bullish on Minnesota, is a major pitching advantage for the home squad. Keep reading to find out more, plus see my top Astros vs Twins predictions and props to target on May 20.

Astros vs Twins Predictions

• Twins moneyline (-146 at Caesars)
• Over 8 runs (-110 at Bet365)

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My two favorite wagers this afternoon are the Twins moneyline and over 8 runs. The starting pitching mismatch is substantial. The Astros hand the ball to Mike Burrows, who carries a bloated 5.72 ERA and 1.53 WHIP over 50.1 innings. The right-hander has labored with traffic on the basepaths all year, allowing a .297 opponent batting average.

The Twins counter with Joe Ryan. He boasts a 3.20 ERA and a stellar 1.01 WHIP across 50.2 innings. Ryan effectively suppresses base runners, holding opposing lineups to a .201 average while striking out 9.24 batters per 9 innings.

The season-long trends support a high-scoring environment. The Under has hit in just 34.0% of Astros games and 30.6% of Twins games this season. The Astros possess a league-worst 5.36 team ERA and 1.54 WHIP. I expect the home offense to generate consistent run production against Burrows and a depleted bullpen.

Mike Burrows vs Joe Ryan

Looking at the MLB starting lineups, Ryan’s 2.83 FIP indicates he has pitched even better than his traditional metrics suggest. His ability to limit hard contact creates a favorable early-inning outlook for the home favorites. Burrows generates a decent 8.23 K/9, but his 4.99 FIP shows a deep susceptibility to damage. He will need to induce significantly more weak contact to quiet a capable opposing lineup.

Astros vs Twins Stats

Houston provides an interesting counterpunch at the plate. When away from Daikin Park, their .272 batting average ranks second in baseball. Star hitters like Yordan Alvarez and Paredes make them dangerous underdogs. However, their inability to stop opposing lineups nullifies much of that offensive upside, and caps their ceiling in the World Series odds.

Astros vs Twins Odds

Odds as of May 20. Claim the BetMGM promo code to bet on the Astros vs Twins today.

Astros vs Twins Props to Target

• Byron Buxton Over 1.5 Total Bases (+108 at DraftKings)

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For my top player prop, I am backing Minnesota’s Byron Buxton Over 1.5 Total Bases at +108 odds. Buxton has mashed 15 home runs with a .586 slugging percentage this year. Getting plus-money on the slugger to record multiple bases against a vulnerable pitcher like Burrows is the best situational angle on the board.

Buxton has faced Burrows just twice per the MLB batter vs pitcher stats, but has recorded a hit in each at-bat. He’s fresh off back-to-back multi-hit games, and has cleared this prop line four times in his last six outings.