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Giants vs Brewers Odds, Picks and Predictions (April 25)

Chris Amberley

by Chris Amberley in MLB Baseball

Apr 25, 2022 · 6:06 AM PDT

Joc Pederson home run celebration
San Francisco Giants' Joc Pederson, right, celebrates with Brandon Crawford after hitting a solo home run off Cleveland Guardians starting pitcher Zach Plesac in the sixth inning of a baseball game, Friday, April 15, 2022, in Cleveland. (AP Photo/David Dermer)
  • The Giants vs Brewers odds favor Milwaukee as -190 moneyline favorites on Monday (April 25, 6:10 pm ET)
  • San Francisco will throw a bullpen game with Sam Long (0-0, 0.00 ERA) acting as the opener, while Milwaukee will counter with Corbin Burnes (1-0, 2.37 ERA)
  • Read below for the Giants vs Brewers odds, analysis and betting prediction

Well this is a first. To make up for the Giants vs Brewers series that was wiped out by the delayed start to the season, the two teams will play one of the three rescheduled games on Monday (April 25), and the other two as part of a doubleheader in early September.

For San Francisco, it simply means prolonging its current road trip by an extra day, but it’s a little more complicated for Milwaukee. The Brewers will fly home from Philly, where they played on Sunday Night Baseball, to face the Giants and then immediately fly back to Pennsylvania to start a series in Pittsburgh on Tuesday.

Giants vs Brewers Odds

Team Moneyline Runline Total
San Francisco Giants +160 +1.5 (-125) O 7 (-110)
Milwaukee Brewers -190 -1.5 (+105) U 7 (-110)

Odds as of April 25th at Caesars Sportsbook.


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Despite the wacky travel schedule, Milwaukee opened as -190 moneyline favorites in a contest that features a total of 7. First pitch is scheduled for 6:10 pm ET at American Family Field in Milwaukee, WI, with clear skies and 50 degree temperatures in the forecast.

Probable Pitchers

The Brewers, a top-seven contender in the World Series odds, will give the ball to Corbin Burns. The right-hander is off to a phenomenal start to the season, posting a 1-0 record, with a tidy 2.37 ERA and a minuscule 0.79 WHIP.

The 27-year-old, who trails only Max Scherzer in the NL Cy Young odds, has allowed just 11 hits in 19 innings of work so far. He’s fresh off back-to-back 7 inning outings, racking up an 18-1 strikeout-to-walk rate along the way.

He’s picked up exactly where he left off in 2021, when he was 11-5 over 28 starts, with a 2.43 ERA and a 0.94 WHIP.

Burnes was 1-0 in two starts against San Francisco last season, yielding only two runs over 13 innings while striking out 14. He’s held the Giants roster to a .191 batting average over 46 at-bats with Joc Pederson and Brandon Belt being the only two players with more than one career hit off him.

Long vs Burnes Stats

Sam Long
Corbin Burnes
0-0 Record 1-0
0.00 ERA 2.37
0.64 WHIP 0.79
.125 OBA .169
4.0 SO/W Ratio 5.5

San Fran meanwhile will throw a bullpen game for the second time in four days. Sam Long, like he did on Friday, will act as the opener although it’s unclear how long he’ll last. Long threw just a couple innings on Friday against the Nationals, but did post multiple 5+ inning outings in 2021 as a rookie.

The Giants bullpen has phenomenal this season, and currently lead all relievers in ERA and strand rate. They allowed just single run over 15.1 innings this past weekend against Washington en route to a three-game sweep.

San Francisco Giants vs Milwaukee Brewers Betting Analysis

San Francisco, who’s on pace to shatter their projection in the MLB win totals, entered the weekend ranked below league average in most offensive categories, but exploded for 24 runs while outscoring the Nats by 18.

They’re 7-3 on their current road trip, recording sweeps of both Washington and Cleveland. Pederson led the way in Sunday’s 12-3 pummelling of the Nats, cranking a pair of home runs. He now has five homers in his first season with the Giants while hitting .364, and is the only San Fran regular batting over .283.

As for their pitching, it’s not just the relievers that have been excelling. The Giants own the second lowest team ERA behind the Dodgers (2.48) and have surrendered the fewest home runs in baseball (7).

Milwaukee has been equally hot recently, winning six of their past seven overall. Like San Fran, this weekend notwithstanding, it’s been primarily pitching and defense that’s carried the positive results.

The Brewers rank top-10 in team ERA, strand rate and K/9. The offense on the other hand, leaves little to be desired. Milwaukee is batting just .209 this season and is averaging only 3.53 runs per game. No regular is hitting above .255 so far, and no player has more than 8 RBI in 16 games.

Giants vs Brewers Last 10 Meetings

Date Away Team Home Team Score
9/2/21 Brewers Giants SF, 5-1
9/1/21 Brewers Giants MIL, 5-2
8/31/21 Brewers Giants MIL, 6-2
8/30/21 Brewers Giants MIL, 3-1
8/8/21 Giants Brewers SF, 5-4
8/7/21 Giants Brewers SF, 9-6
8/6/21 Giants Brewers MIL, 2-1
7/14/19 Giants Brewers SF, 8-3
7/13/19 Giants Brewers MIL, 5-4
7/12/19 Giants Brewers SF, 10-7

San Francisco Giants vs Milwaukee Brewers Pick

Given the exceptional pitching from both clubs, and the fact that a top Cy Young candidate is on the bump we have to look at the under in this matchup.

Only four of Milwaukee’s first 16 games have exceeded the total, while the under is 9-6-1 in Giants contests.

Each of Burnes’ last two starts failed to produce more than seven runs, and dating back to last season he’s coughed up more than three runs in only one of his last 14 starts.

Pick: Under 7 (-110)

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