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Yankees vs Guardians Odds, Picks and Runline (April 11)

John Perrotto

by John Perrotto in MLB Baseball

Updated Apr 10, 2023 · 8:24 PM PDT

Cleveland Guardians players celebrating after a win.
Apr 10, 2023; Cleveland, Ohio, USA; Cleveland Guardians catcher Mike Zunino (10) and relief pitcher Emmanuel Clase (48) celebrate a win over the New York Yankees at Progressive Field. Mandatory Credit: David Richard-USA TODAY Sports
  • The Yankees are -160 road favorites over the Guardians on Tuesday night
  • Gerrit Cole (2-0, 0.73) will start for the Yankees against Hunter Gaddis (0-0, 3.72)
  • A look at the Yankees vs Guardians matchup and odds can be found below with a pick

The Cleveland Guardians will look to make it three wins in a row when they host the New York Yankees at 6:10 p.m. ET Tuesday in the middle game of a three-game series at Progressive Field.

The Guardians (7-4, 2-2 home) won the series opener 3-2 on Monday night. The Yankees (6-4, 2-2 road) had won their previous two games.

Yankees vs Guardians Odds

Team Moneyline Runline Total
New York Yankees -160 -1.5 (+105) Over 7.5 (-115)
Cleveland Guardians +135 +1.5 (-130) Under 7.5 (-105)

The Yankees are -160 favorites over the Guardians on the moneyline on Tuesday night in the MLB odds, giving them a 61.54% implied win probability. New York has +750 World Series championship odds and Cleveland is listed at +2200.

The temperature is expected to 66 at gametime with a low of 56, cloudy skies and wind from the southwest at 11 mph.


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Odds as of April 10th at BetMGM.

Yankees vs Guardians Probable Pitchers

Gerrit Cole (2-0, 0.73) will pitch for the Yankees and oppose rookie Hunter Gaddis (0-0, 3.72). Both will be pitching on five days of rest.

Cole vs Gaddis

Gerrit Cole
Hunter Gaddis
2-0 Record 0-0
0.73 ERA 3.72
2.12 xERA 2.32
0.89 WHIP 0.93
3.80 SO/W 2.67

Cole will look to continue his fine start to the season after beating the Phillies last Wednesday in Philadelphia. He limited the defending National League champions to one run on three hits in 6.1 innings with eight strikeouts and three walks.

The Guardians have struggled against Cole. He has a 9-2 record and 2.76 ERA against them in 12 career starts.

Cole, whose AL Cy Young odds are +700, has just a slightly higher ERA on the road (3.26) in his career than he does at home (3.17). His ERA is 3.10 in night games and 3.46 in the day.

Gaddis pitched six shutout innings of one-hit ball last Wednesday against the Athletics in Oakland but wound up still looking for his first career win as he had a no-decision. He struck out four and walked two.

This will be Gaddis’ first time facing the Yankees in his nascent career.

Gaddis has struggled at Progressive Field with an 18.41 ERA as compared to 3.72 on the road. He has a 6.30 mark in the day and a 15.42 ERA at night.

Batting Average vs Starting Pitchers

Guardians Batters Batting Average vs Gerrit Cole
Jose Ramirez .296
Josh Naylor .278
Andres Gimenez .267
Steven Kwan .182
Oscar Gonzalez .167
Mike Zunino .152
Myles Straw .125
Amed Rosario .077
Will Brennan .000
Gabriel Arias .000
Josh Bell .000
Meibrys Viloria .000

Guardians first baseman Josh Naylor has three home runs and a double off Cole while going 5 for 18 (.273). However, catcher Mike Zunino is a .162 hitter (5 for 33) with two doubles, one homer and 16 strikeouts and shortstop Amed Rosario is 1 for 13 (.077) with five punchouts.

Yankees vs Guardians Betting Outlook

Josh Naylor’s sacrifice fly in the seventh inning broke a 2-2 tie and lifted the Guardians to victory on Monday night.

The Guardians had just four hits and three were doubles by Mike Zunino. Gleyber Torres had a double and a triple for the Yankees.

Yankees vs Guardians Last 10 Games

Date Home Team Away Team Score
4/10/23 Guardians Yankees CLE, 3-2
10/18/23 Yankees Guardians NYY, 5-1
10/16/23 Guardians Yankees NYY, 4-2
10/15/23 Guardians Yankees CLE, 6-5
10/14/23 Yankees Guardians CLE, 4-2
10/11/23 Yankees Guardians NYY, 4-1
7/3/22 Guardians Yankees CLE, 2-0
7/2/21 (2) Guardians Yankees NYY, 6-1
7/2/22 (1) Guardians Yankees NYY, 13-4
4/24/22 Yankees Guardians NYY, 10-2

The Yankees have a 22-13 record against the Guardians since 2018, including winning postseason series in 2020 and 2022.

Yankees vs Guardians Prediction

Cole has been outstanding in his first two starts and has an outstanding track record against the Guardians. It’s hard to bet against him even as a substantial road favorite.

Pick: Yankees -160 ML

Season Record: 6-3 (+2.0 units) ML

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