Best 49ers vs Cardinals Same-Game Parlay for MNF
- The 49ers and Cardinals clash in an NFC West battle to conclude Week 11 on Monday Night Football
- We’ve included Jimmy Garoppolo and Christian McCaffrey in tonight’s MNF SGP
- See the +295 odds in this 49ers vs Cardinals same-game parlay for Monday Night Football on November 21st
Tonight, the 5-4 San Francisco 49ers can jump atop the NFC West standings against divisional rival Arizona Cardinals, who are 4-6. The underdog Cardinals have won three of their last four against San Fran. It’ll be made that much harder with QB Kyler Murray (hamstring) expected to miss this one. This game will be contested in a neutral location in Mexico City and we’re going heavy with 49ers props in our 49ers vs Cardinals same-game parlay.
49ers vs Cardinals Same-Game Parlay Picks
| Pick | Odds |
|---|---|
| 49ers Moneyline | -475 |
| Christian McCaffrey Anytime Touchdown | -150 |
| Jimmy Garoppolo Over 249.5 Passing Yards | -105 |
| SAME-GAME PARLAY ODDS | +295 |
Odds as of November 21. Lock in the latest DraftKings Sportsbook promo code here to get the best bonus for MNF before making your SGP. Right now DraftKings is offering up to a 100% profit boost with Stepped Up SGPs for Week 11!
Tonight’s SGP has three legs, including the 49ers moneyline, along with Christian McCaffrey anytime TD and Jimmy Garoppolo over 249.5 passing yards.
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The public is favoring the Cardinals to cover the 10-point spread. With 57% of bets on them, while 79% of 49ers vs Cardinals public betting trends are pointing to wagers on San Fran to win on the moneyline. With respect to the game total, 70% of bets have been placed on over 42.5 points.
The 49ers are the fourth choice in the Super Bowl odds at +850, while the Cardinals are massive longshots at +15000.
SGP Pick #1: 49ers Moneyline
It’s been something of a strange year for San Fran, as they sit at 5-4. They’ve won their last two contests against both LA teams by a combined 23 points, pointing to them getting things on track. They’re the fifth-best team in the NFL, according to Pro Football Focus (5th on D, 11th on offense).
The 49ers found their new STAR on defense. 😤@TalanoaHufanga | @49ers
(by @CourtyardHotels) pic.twitter.com/NXQLEbtCel
— NFL (@NFL) November 17, 2022
Our model has this game going in San Fran’s favor, with the 49ers predicted to win 25.5-14 over the Cardinals. Arizona did win their last game 27-17 against the Rams with Colt McCoy under center, but he’s expected to face a much sterner test as he replaces Kyler Murray for a second straight week. A 49ers victory has extra significance for them – if they earn the W, they’ll take over the Seahawks for first place in the NFC West.
SGP Pick #2: Christian McCaffrey Anytime Touchdown
In the three games since Christian McCaffrey came over to San Fran in a midseason trade, he’s racked up four TDs. After recording none in his first contest, he threw for a TD, ran for one, and caught one against the Rams. He then found paydirt last game as well against the Chargers. That’s something to consider in the 49ers vs Cardinals picks.
In three career games against the Cards, McCaffrey has found the end zone on two occasions. Last week, the Niners actually had a timeshare in the backfield, with McCaffrey getting 18 touches compared to Elijah Mitchell’s 19. There should still be plenty of opportunities for McCaffrey to find the end zone against the 26th-ranked run defense.
Christian McCaffrey says splitting carries with Elijah Mitchell is "100 percent" beneficial pic.twitter.com/VWMystZYID
— KNBR (@KNBR) November 20, 2022
The 49ers vs Cardinals injury report suggests a relatively clean bill of health for San Fran. With DL Arik Armstead the only player ruled out of this one. The Cards, of course, likely won’t have Murray, TE Zach Ertz is out for the season with a knee injury, and WR DeAndre Hopkins (hamstring) is dealing with a lingering injury. CB Byron Murphy and OL DJ Humphries have been ruled out.
SGP Pick #3: Jimmy Garoppolo Over 249.5 Passing Yards
Jimmy Garoppolo has played five career games against the Cardinals. And he’s gone over the listed 249.5 passing yards total each time. His numbers are as follows – 264, 317, 424, 259, 326.
He’s also gone over that number in three of his last five games. With the two that he didn’t being awfully close with 235 and 240 yards, respectively. According to Pro Football Focus, the Cardinals are 19th in coverage on the campaign, and they’ve given up the tenth-highest passing yards/game in the league. He must definitely be considered in your 49ers vs Cardinals props for this Monday Night Football affair.
49ers vs Cardinals Same-Game Parlay Odds (+295)
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Michael "Hound Dog" Harrison is well known in the sports industry as the resident statistician for the SC with Jay Onrait Show. He has worked at TSN for over 16 years, where he's been featured on Sportscentre, That's Hockey, That's Hockey 2Nite, The Masters preview shows, and several more.
