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  1. Home
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  7. San Francisco 49ers VS Arizona Cardinals

San Francisco 49ers VS Arizona Cardinals

Football Icon
Odds & Matchup Stats
San Francisco Logo

San Francisco

5-4

vs
Arizona Logo

Arizona

4-6

November 21, 2022

8:15 PM EST

Estadio Azteca

Closing Odds

Matchupfanduel Logodraftkings Logobetmgm LogoBet %Money %Consensus
San Francisco Team LogoSan Francisco
-9.5 -110
-9.5 -110
-10 -110
47%
Arizona Team LogoArizona
+9.5 -110
+9.5 -110
+10 -110
53%

This game was played on November 21, 2022. Closing Odds were accurate as of 8:15 pm. Check out upcoming NFL Odds.

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Predicted Score

San Francisco Logo

25.5 - 14

Arizona Logo

Our formula predicts the San Francisco 49ers will beat the Arizona Cardinals by a score of 25.5–14.

Win Probability

San Francisco Logo

77.9% - 22.1%

Arizona Logo

The 49ers have a 77.9% chance of beating the Cardinals based off the odds.

Pick

San Francisco Logo

San Francisco To Win

49ers COVER the -9.5 spread and the total is UNDER 43

SportsBettingDime’s formula is picking the 49ers (-9.5) to cover the spread, and has the total going Under 43.

Consensus
Picks

San Francisco Team Logo
Arizona Team Logo
85%
15%
47%
53%
60%
40%
MLATSO/U

53% of the bets placed against the spread are on the Cardinals ; the moneyline splits show 85% of the moneyline bets are on the 49ers at -420 odds; 60% of the public bets are on the Over ().

Trends

San Francisco Team Logo

San Francisco

Arizona Team Logo

Arizona

RETURN ON INVESTMENT: LAST 10 GAMES

Date
ML
ATS
OVER
UNDER

KEY INSIGHT: Available exclusively for SBD Plus users. Login or Register for FREE.

San Francisco Team Logo

San Francisco

RETURN ON INVESTMENT: LAST 10 GAMES

Date
ML
ATS
OVER
UNDER

KEY INSIGHT: Available exclusively for SBD Plus users. Login or Register for FREE.

Arizona Team Logo

Arizona

RETURN ON INVESTMENT: LAST 10 GAMES

Date
ML
ATS
OVER
UNDER

KEY INSIGHT: Available exclusively for SBD Plus users. Login or Register for FREE.

Understanding Return on Investment Trends

SBD Sharp measures the profitability of teams over time. A positive percentage indicates that betting the team has been profitable in recent games. Visit SBD Sharp for a detailed explanation of ROI trends or register for your free SBD Plus account account today.

Futures Trackers

Track the Super Bowl odds all season and see how San Francisco and Arizona compare to the top contenders.

Learn More

Stats

Records

San Francisco Logo

San Francisco

Arizona

Arizona Logo
5-4

Overall

4-6
2-3

Away/Home

1-4
15-3Fav/Udog3-11

Each team's record on the moneyline, spread, and over/under, with home and road splits for each.

Team Leaders

San Francisco Logo

Jimmy Garoppolo

Kyler Murray

Arizona Logo
241.4

Passing YPG

240.9
11

Passing TDs

12
4

INTs

6

Compare key stats for each team's most impactful players.

Head to Head

San Francisco Logo

San Francisco

Arizona

Arizona Logo
Points Per Game (PPG)
22
23
Yards Per Game (YPG)
360
333.7
Passing Yards Per Game
236.3
220.6
Rushing Yards Per Game
123.7
113.1
Turnovers Committed
13
9
Points Per Game Allowed
18.1
25.8
Yards Per Game Allowed
280.6
357.6
Passing Yards Per Game Allowed
197.9
247.1
Rushing Yards Per Game Allowed
82.7
110.5
Turnovers Forced
10
14

Directly compare team stats for the most important metrics.

Injuries

San Francisco Team Logo

San Francisco

Arizona Team Logo

Arizona

PlayerStatus

Arik Armstead

Did Not Participate In Practice

Foot

11/18/2022 @ 7:0PM EST

Nick Bosa

Full Participation In Practice

NIR - Rest

11/18/2022 @ 7:0PM EST

Samson Ebukam

Limited Participation In Practice

Quadriceps

11/18/2022 @ 7:0PM EST

Charvarius Ward

Did Not Participate In Practice

NIR - Personal

11/18/2022 @ 7:0PM EST

Trent Williams

Full Participation In Practice

NIR - Rest

11/18/2022 @ 7:0PM EST

Danny Gray

Full Participation In Practice

Ankle

11/18/2022 @ 7:0PM EST

-

-

-

-

-

-

-

-

San Francisco Team Logo

San Francisco

PlayerStatus

Arik Armstead

Did Not Participate In Practice

Foot

11/18/2022 @ 7:0PM EST

Nick Bosa

Full Participation In Practice

NIR - Rest

11/18/2022 @ 7:0PM EST

Samson Ebukam

Limited Participation In Practice

Quadriceps

11/18/2022 @ 7:0PM EST

Charvarius Ward

Did Not Participate In Practice

NIR - Personal

11/18/2022 @ 7:0PM EST

Trent Williams

Full Participation In Practice

NIR - Rest

11/18/2022 @ 7:0PM EST

Danny Gray

Full Participation In Practice

Ankle

11/18/2022 @ 7:0PM EST

-

-

-

-

-

-

-

-

Arizona Team Logo

Arizona

PlayerStatus

Byron Murphy Jr.

Did Not Participate In Practice

Back

11/18/2022 @ 7:0PM EST

Max Garcia

Limited Participation In Practice

Shoulder

11/18/2022 @ 7:0PM EST

Markus Golden

Full Participation In Practice

Illness

11/18/2022 @ 7:0PM EST

Colt McCoy

Full Participation In Practice

Knee

11/18/2022 @ 7:0PM EST

Kyler Murray

Limited Participation In Practice

Hamstring

11/18/2022 @ 7:0PM EST

Matt Prater

Full Participation In Practice

Right Hip

11/18/2022 @ 7:0PM EST

Budda Baker

Full Participation In Practice

Ankle

11/18/2022 @ 7:0PM EST

Zach Ertz

Did Not Participate In Practice

Knee

11/18/2022 @ 7:0PM EST

DeAndre Hopkins

Limited Participation In Practice

Hamstring

11/18/2022 @ 7:0PM EST

D.J. Humphries

Did Not Participate In Practice

Back

11/18/2022 @ 7:0PM EST

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