NFL Odds for Week 7 – Opening Betting Lines & Spreads for All Games

• The NFL Week 7 schedule kicks off with Saints vs Cardinals on Thursday Night Football (Oct. 20th)
• Tampa Bay is the biggest favorite on the board, laying 10 points at Carolina
• You can find the opening odds for all the Week 7 games below, plus early predictions on which lines may see the most movement

Believe it or not, it’s time to look ahead to Week 7 on the NFL schedule already. The slate begins on Thursday Night football with a Saints versus Cardinals clash, and features six matchups where teams are laying at least a full touchdown to their opponent in the NFL odds.

Week 6 by comparison, featured just three teams who were favored by 7 or more points, and only one of them were able to cover the spread.

No team is laying more points than Tampa Bay in Carolina, while the Chiefs-49ers rematch of Super Bowl 54 projects to be the tightest contest of the week.

Before we dive into each of those matchups individually, check out all the Week 7 opening odds below.

NFL Week 7 Opening Odds

Odds as of October 16th at DraftKings Sportsbook. Claim the DraftKings Sportsbook promo code.

The Buccaneers opened as slate-high 10-point favorites over the Panthers, while Kansas City, along with Tennessee and Jacksonville are the shortest favorites on the board at -2.5.

The only total north of 50 belongs to the Seahawks and Chargers at 52, while the Bears and Patriots 39.5 point total is the lone over/under south of 40.

DRAFTKINGS SPORTSBOOK

Offer

T&Cs

Sign Up Today & Receive Up to
$1,050 in Bonuses!

Excludes MA.

LOCK IN PROMO

SIGNUP PROMO

SIGN UP
& GET $1,050

BONUS BETS + DEPOSIT BONUS

BET NOW

Biggest and Smallest Week 7 Spreads

If Week 6 is any indication, Tom Brady and co. should not be laying 10 points on the road, even to the Panthers. The Bucs closed as 9.5-point favorites in Week 6 versus the one-win Steelers, but lost outright to Mitch Trubisky, who came on in relief.

Mitch Trubisky just did what Gisele couldn’t…keep Tom Brady off the field

— Brad Williams (@funnybrad) October 16, 2022

Since covering in Weeks 1 and 2, Tampa Bay has failed to beat the spread in four straight games. They were favored in each of those contests and lost outright in three of them.

The counter argument would be that Carolina is 1-5 both straight up and against the spread in 2022, and has failed to cover in 17 of their 23 outings since the start of last season.

As mentioned, three teams are favored by 2.5 points in Week 7, but the Chiefs-49ers matchup is the most compelling. Both teams are coming off losses, although Kansas City’s was to the Super Bowl favorite Bills.

The Kansas City Chiefs are SO MUCH FUN to watch#PMSOverreactionMonday pic.twitter.com/jhVstMaPm2

— Pat McAfee (@PatMcAfeeShow) October 3, 2022

This game will be a classic strength versus strength matchup, as the Chiefs entered Week 6 ranked third on offense per DVOA and first in points per game. San Fran meanwhile, entered as the league’s top defense per DVOA, and had surrendered the fewest points through five games.

Highest and Lowest Week 7 Totals

All the Seattle offense needed to do to flourish was to get rid of Russell Wilson. The Seahawks entered Week 6 as the top graded offense per DVOA, and have seen the majority of their games sail over the total thanks to Geno Smith’s resurgence and the league’s worst scoring defense.

Don't write Geno Smith off ✍️ pic.twitter.com/n8TfBfoq3R

— B/R Gridiron (@brgridiron) October 15, 2022

Seattle is allowing 30.8 points per game, and won’t offer much resistance to Justin Herbert and the Chargers. LA’s passing attack ranks sixth per DVOA, while each of their last three games have gone over the total entering their Week 6 Monday Night Football tilt.

Chicago set offensive football back multiple decades with its 12-7 loss to Washington to kick-off Thursday Night Football. So what does the NFL do, subject us to the Bears in primetime once again in Week 7.

Justin Fields goal line pic.twitter.com/n9RCJtS1so

— Pardon My Take (@PardonMyTake) October 14, 2022

Chicago ranks 29th on offense per DVOA, while Justin Fields has the worst passer rating of any starting QB. They average a pitiful 15.5 points per game, so it’s little surprise this total opened so low.

Also working in favor of a low scoring game is New England’s run first mentality and strong defense. The Pats run the ball at the NFL’s seventh highest rate, and rank ninth defensively per DVOA.

Early Week 7 Predictions

Falcons vs Bengals Early Odds and Prediction

The lookahead line for this game was Bengals -7, and it opened Sunday night at Cincy -6.5. That still feels too high, and it’s hard to imagine bettors running to the window to bet on the Bengals.

Cincinnati barely survived a New Orleans squad in Week 6 that was missing its starting quarterback, top-two receivers and best corner. If not for some horrendous missed tackles on the Ja’Marr Chase game winning touchdown, the Bengals could be staring at 2-4 start.

JA'MARR CHASE ARE YOU KIDDING ME 😱

(via @Bengals)pic.twitter.com/44m16UlDVu

— SportsCenter (@SportsCenter) October 16, 2022

Atlanta meanwhile, not only beat the spread again on Sunday, but upset the visiting 49ers. The Falcons ran all over San Francisco in their 28-14 win, while their defense forced three Niner turnovers.

The Falcons are a perfect 6-0 against the spread, the only undefeated team in the league versus the number.

Pick: Falcons -6.5 (-110)

Packers vs Commanders Early Odds and Prediction

As a Packers fan let me tell you this team, it ain’t it. Green Bay is as public of a team as you’ll find, but even diehard Packers fans can’t be excited to bet on Aaron Rodgers and co. right now.

The Packers have scored 10 total points in their last six quarters of play, and are fresh off back-to-back losses against both New York teams. Rodgers is on pace for one of his worst statistical seasons as a starter, and has already absorbed 15 sacks, half the amount he took in 16 contests last year.

Aaron Rodgers lost at home for the first time in 16 games.

Tom Brady lost to the Steelers for just the 4th time in 16 games.

Lamar Jackson lost to an NFC team for the first time ever.

An unpredictable Sunday already.

— Field Yates (@FieldYates) October 16, 2022

Washington on the other hand, is a bottom-five team per DVOA, but they’ve won just one fewer game than Green Bay and will be well rested having played last Thursday night.

There is not a team in the NFL that the Packers should be laying 5.5 points against right now, especially on the road. Expect this number to move towards Washington throughout the week.

Pick: Washington Commanders +5.5 (-110)