Upcoming Match-ups

NFL Week 12 Odds – Opening Betting Lines & Spreads for All Games

Robert Duff

by Robert Duff in NFL Football

Updated Nov 19, 2023 · 5:41 PM PST

In the NFL Week 12 opening odds, the Arizona Cardinals were favored for the first time in 20 games.
Nov 19, 2023; Houston, Texas, USA; Arizona Cardinals quarterback Kyler Murray (1) huddles against the Houston Texans in the second half at NRG Stadium. Mandatory Credit: Thomas Shea-USA TODAY Sports
  • NFL Week 12 kicks off with three Thursday games on Thanksgivng
  • For the first time ever, there’s a Black Friday contest between the Dolphins and Jets
  • A look at all the opening NFL Week 12 odds can be found below with early predictions

The NFL Week 12 slate of games is offering some traditional rivalry fare on Thanksgiving to kick off the week, with the Green Bay Packers in Detroit to face the Lions and the Dallas Cowboys playing host to the Washington Commanders.

Baltimore is back in prime time for a second straight week. Fresh off their TNF divisional win over the Bengals, the Ravens are in Los Angeles to face the Chargers on Sunday Night Football.

There’s also a Super Bowl 42 and 46 rematch on tap as the New England Patriots visit the New York Giants. It’s unlikely, though, that many will be clamoring to check out this tilt between the 2-8 Patriots and the 3-8 Giants.

Opening NFL Week 12 Odds

Team Moneyline Spread Over/Under
Green Bay Packers +290 +7.5 (-115) Over 45.5 (-110)
Detroit Lions -360 -7.5 (-105) Under 45.5 (-110)
Team Moneyline Spread Over/Under
San Francisco 49ers -280 -6.5 (-110) Over 43.5 (-115)
Seattle Seahawks +230 +6.5 (-110) Under 43.5 (-105)
Team Moneyline Spread Over/Under
Washington Commanders +425 +11 (-110) Over 46.5 (-115)
Dallas Cowboys -550 -11 (-110) Under 46.5 (-105)
Team Moneyline Spread Over/Under
Miami Dolphins -360 -7 (-120) Over 42.5 (-105)
New York Jets +290 +7 (EVEN) Under 42.5 (-115)
Team Moneyline Spread Over/Under
Tampa Bay Buccaneers +105 +1.5 (-110) Over 42.5 (-110)
Indianapolis Colts -125 -1.5 (-110) Under 42.5 (-110)
Team Moneyline Spread Over/Under
New England Patriots -185 -3.5 (-110) Over 33.5 (-110)
New York Giants +155 +3.5 (-110) Under 33.5 (-110)
Team Moneyline Spread Over/Under
Pittsburgh Steelers EVEN +1 (-110) Over 35.5 (-110)
Cincinnati Bengals -120 -1 (-110) Under 35.5 (-110)
Team Moneyline Spread Over/Under
Carolina Panthers +165 +4 (-110) Over 37.5 (-105)
Tennessee Titans -195 -4 (-110) Under 37.5 (-115)
Team Moneyline Spread Over/Under
Jacksonville Jaguars -110 -1 (-110) Over 45.5 (-115)
Houston Texans -110 +1 (-110) Under 45.5 (-105)
Team Moneyline Spread Over/Under
New Orleans Saints -110 +1 (-120) Over 41.5 (-105)
Atlanta Falcons -110 -1 (EVEN) Under 41.5 (-115)
Team Moneyline Spread Over/Under
Los Angeles Rams -115 -1 (-120) Over 46 (-115)
Arizona Cardinals -105 +1 (-102) Under 46 (-105)
Team Moneyline Spread Over/Under
Cleveland Browns -102 +1.5 (-110) Over 36.5 (-110)
Denver Broncos -122 -1.5 (-110) Under 36.5 (-110)
Team Moneyline Spread Over/Under
Buffalo Bills +142 +3.5 (-115) O 47.5 (-110)
Philadelphia Eagles -170 -3.5 (-105) U 47.5 (-110)
Team Moneyline Spread Over/Under
Kansas City Chiefs -455 -10 (-110) Over 44 (-110)
Las Vegas Raiders +350 +10 (-110) Under 44 (-110)
Team Moneyline Spread Over/Under
Baltimore Ravens -185 -4 (-110) Over 46 (-110)
Los Angeles Chargers +154 +4 (-110) Under 46 (-110)
Team Moneyline Spread Over/Under
Chicago Bears +150 +3.5 (-110) Over 45.5 (-110)
Minnesota Vikings -180 -3.5 (-110) Under 45.5 (-110)

The NFL odds for Week 12 are showing the Dallas Cowboys as the biggest favorites. They’re the 10-point chalk in their game at home to the Commanders.

 

ESPN BET


Get a $1,000 Bet Reset at ESPN BET if Your First Bet Loses!

Must manually enter promo code DIME to claim offer.

LOCK IN PROMO
CODE: DIME
CODE: DIME
SIGNUP OFFER
USE PROMO CODE
DIME

FIRST BET RESET UP TO $1,000

GET OFFER NOW

Odds as of November 19 at ESPN Sportsbook. Use this ESPN BET promo code to bet on Week 12 NFL action and unlock $250 in bonus bets when using promo code ‘DIME’ at sign-up.

Four games are opening with the lowest odds, all with betting lines of one points. They include the Los Angeles Rams as the 1.5-point away chalk over the Arizona Cardinals. Arizona was briefly the 1-point favorite in this game. It was the first time in 20 games that the Cardinals are set as the favorites in the betting line.

The Week 12 total high of 47.5 points arrives with the contest between the Buffalo Bills and the reigning NFC Champion Philadelphia Eagles. The smallest in the 33.5 points assigned to the New England Patriots vs New York Giants game.

The reigning-champion Chiefs continue to lead the Super Bowl odds at +450. Philadelphia (5-2-2) owns the best ATS cover rate in the NFL at 71.4%.

Ravens vs Chargers Early Odds & Predictions

The Chargers are 0-3 against the spread as an underdog this season, so opening as 4-point home underdogs doesn’t bode well for Justin Herbert and company.

Baltimore, though, is just 2-3 ATS in the last five against the Chargers. Then again, the Ravens are 1-0 ATS against them in LA. Baltimore is 3-2 ATS on the road this season.

Pick: Ravens -4 (-110)

Opening Bears vs Vikings Odds & Predictions

With QB1 Justin Fields back from his dislocated thumb last week, Chicago put a scare into the NFC North-leading Detroit Lions before succumbing 31-26. Could the Bears do it again facing Minnesota, the #2 team in the division?

Chicago 4-1 ATS in the last five games at Minnesota. The Bears are 2-0 SU and 1-1 ATS in prime time this season. They’re 0-3 SU and 1-2 ATS within the division.

Pick: Vkings -3.5 (-110)

Expected Week 12 Line Movement

Oddsmakers briefly favoring the Cardinals for the first time since they were a 2-point home pick over Seattle on Oct. 16, 2022, oddly enough saw the Seahawks are playing a role again in Arizona being favored.

Rams QB1 Matthew Stafford was injured in Sunday’s game against Seattle. He was able to finish out LA’s victory, though, so that’s likely why the line swing back to LA.  This will be a developing story to track during the week.

Pick: Rams -1 (-110)

ESPN BET


Get a $1,000 Bet Reset at ESPN BET if Your First Bet Loses!

Must manually enter promo code DIME to claim offer.

LOCK IN PROMO
CODE: DIME
CODE: DIME
SIGNUP OFFER
USE PROMO CODE
DIME

FIRST BET RESET UP TO $1,000

GET OFFER NOW
Author Image