AC Milan vs Inter Milan Predictions, Odds, Lineups – Champions League Semifinals Leg 1

• Italian giants meet in massive UCL derby clash in San Siro stadium at 3:00 pm ET on Wednesday
• Inter Milan has two wins over its city rival this season with AC Milan winning once
• See our AC Milan vs Inter Milan prediction, odds and best bets for the Champions League semifinal Leg 1

A classic Italian derby takes place in the Champions League semifinal first-leg collision of AC Milan vs Inter Milan on Wednesday.

The city’s San Siro stadium will be rocking for this huge clash, with the second leg taking place at the same venue the following Tuesday.

Each team shares the iconic venue – with AC Milan the designated home team for the first leg.

Inter Milan currently sits in fourth place in Serie A with last season’s champion AC Milan one place below.

Meanwhile, these sides have won one match apiece against each other in the Italian league this season – with Inter Milan also successful in a meeting in the Super Coppa Italia.

Moreover, this tie ensures that one of the storied Milan clubs will compete in the Champions League final against Real Madrid or Manchester City in Istanbul in June.

AC Milan vs Inter Milan Odds

At Draftkings, Inter Milan is a +150 favorite for a win in the first leg of this colossal fixture.

Meanwhile, AC Milan is priced at +210. The draw is rated at +215. Kick-off at San Siro is at 3:00 pm ET.

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Furthermore, Manchester City is the -165 favorite in the Champions League odds. Real Madrid is +350 with both Milan clubs at +700.

Odds as of May 9 at DraftKings Sportsbook. Claim this DraftKings Sportsbook promo code before betting on the match to claim a unique sign-up bonus.

AC Milan vs Inter Milan Over/Under & Spread

Inter Milan has scored no fewer than 14 times during a current run of four straight wins in Serie A – conceding just once.

It also scored five times in its Champions League quarter-final defeat of Benfica, conceding three.

AC Milan has not been so prolific with just six league goals in its last four Serie A fixtures, with two conceded.

It's time to prepare for #InterMilan 🖤💙
How much do you know about the #DerbyMilano? 🤔#ForzaInter #UCL

— Inter (@Inter_en) May 8, 2023

It was a 2-1 aggregate winner over Napoli in the UCL  last eight.

This, however, is likely to be a tight affair with odds of +130 for there to be at least three goals (TG Ov 2.5.)

There are attractive odds of +750 for the game to be goalless (TG Un 0.5.)

Meanwhile, among the spread offers, Inter Milan is priced at +425 to win by at least two goals (Spread -1.5.)

AC Milan is priced at +190 to win by one goal (Spread -0.5.)

AC Milan vs Inter Milan Preview

Inter has won its last four Serie A games – with an impressive 2-0 away win at Roma last weekend.

This run has wiped out the worries caused by a prior run of five league games without a win.

It was a 2-0 winner away at Benfica in the UCL quarterfinal first leg. However, there were some unexpected defensive jitters in the return match, which was drawn 3-3 in Milan.

🔴⚫️ Fikayo Tomori (25) reached 100 appearances for AC Milan and also gave a message to the fans in full Italian.

Paulo Maldini: "As I always say, this is the first of many big milestones you can achieve in the Rossoneri shirt." pic.twitter.com/Fc58LTnfXg

— EuroFoot (@eurofootcom) May 2, 2023

Therefore, its domestic form suggests it is heading into this meeting with its great city rival in the best form of the two sides.

AC Milan impressed in the UCL last eight – winning 1-0 at home against Napoli and holding it 1-1 in the away leg.

Napoli has now been crowned the new Serie A Champion.

However, in the Italian league, AC Milan has won twice and drawn twice in its last four games – succeeding 2-0 at home against Lazio last weekend.

AC Milan vs Inter Milan Statistics

*Statistics from UCL 2022-23.

Lautaro Martinez To Score Odds

Inter Milan’s Argentine striker Lautaro Martinez has scored five times in his last four Seria A appearances, with a total for the season of 19. He also has two UCL goals.

He is the favorite to score in this tie at +185 – or +450 to score first or last.

🚨 Manchester United are willing to offer €50m + Anthony Martial to Inter Milan for Lautaro Martínez this summer.

(Source: Calciomercato) pic.twitter.com/ezNb5FWJkQ

— Transfer News Live (@DeadlineDayLive) May 4, 2023

Team-mate Ronelue Lakuku meanwhile, is the second favorite at +230.

For AC Milan, moreover, the most favored striker is the veteran Frenchman Olivier Giroud at +260; or +600 to score first or last.

He has five UCL goals this season with eight in Serie A.

AC Milan vs Inter Milan History

Inter Milan was a 3-0 winner when these teams met in the final of the Super Coppa Italia in Saudi Arabia in January.

Meanwhile, AC Milan won 3-2 in the Serie A derby at San Siro last September. Subsequently, Inter Milan was a 1-0 winner at the same venue last February.

AC Milan vs Inter Milan Line-Ups & Injuries

AC Milan projected line-up: Maignan; Calabria, Tomori, Kjaer, Hernandez; Tonali, Krunic; Diaz, Bennacer, Saelemaekers; Giroud

 AC Milan Injuries: Ibrahimovic, Pobrega

 Inter Milan projected line-up: Onana; Darmian, Acerbi, Bastoni; Dumfries, Barella, Brozovic, Mkhitaryan, Dimarco; Martinez, Lukaku

 Inter Milan Injuries: Dalbert, Skriniar

 AC Milan vs Inter Milan Prediction

 Although such derbies can often be tight, Inter Milan is in ravenous goalscoring form domestically and can make that count against its greatest rival.

 It is highly feasible that Inter Milan could claim a comfortable win by at least two goals.

 Pick: Inter Milan +425 (Spread -1.5)