Chargers vs Lions Picks, Predictions, Betting Lines & How to Watch 2025 Hall of Fame Game

• The Los Angeles Chargers and Detroit Lions meet in the annual Hall of Fame Game tonight
• Former #3 pick Trey Lance is expected to see ample playing time for the Chargers
• See the best Chargers vs Lions picks and predictions, plus the updated odds and betting lines and details on how to watch

The Los Angeles Chargers (5-11 SU in preseason since 2019) and Detroit Lions (5-11 SU in preseason since 2019) will meet at Tom Benson Hall of Fame Stadium in Canton, OH, for the 2025 Hall of Fame Game, which kicks off the start of NFL preseason.

Below, I’ll detail how to watch the Hall of Fame Game, provide the latest Chargers vs Lions betting lines, and set out my favorite picks for LAC vs DET tonight.

Jump to: How to Watch LAC vs DET | Best LAC vs DET Odds | LAC vs DET Picks

How to Watch Hall of Fame Game: Chargers vs Lions

Tonight’s Hall of Fame Game will be broadcast live on NBC at 8:00 pm ET. It will also be streamed live on Peacock.

Viewers in Canada will be able to watch Chargers vs Lions on TSN2.

LAC vs DET Betting Lines

The Chargers vs Lions odds have been bouncing around for the last 48 hours. The Lions opened as slim one-point favorites and then were bet up to -2.0 before the line came back down as far as -0.5 as of Thursday morning. Detroit is still favored by 1.5 at bet365, which is the best ATS price Chargers bettors can currently find. On the moneyline, Chargers bettors can get +105 at Caesars, bet365, or BetMGM. Lions moneyline bettors can find the best price (-120) at FanDuel.

The total has seen the most change since the odds opened. The O/U was just 32.5 at the outset, but is now as high as 34.0 in Thursday’s NFL odds.

Los Angeles Chargers vs Detroit Lions Picks & Predictions

• Chargers moneyline (+105) at bet365
• Under 34.0 (-105) at Caesars

The Chargers were only 1-2 straight-up in preseason last year, their first with Jim Harbaugh on the sideline. But overall, Harbaugh has been an excellent bet in preseason action. He hasn’t been quite as good as his brother John, who’s an absurd 44-17 SU during his tenure with Baltimore, but Jim is still a profitable 11-8 during his time with the Niners and Chargers.

Dan Campbell, on the other hand, is just 5-7 SU as a head coach in the preseason, all with the Lions.

The Chargers also had a stronger, and more plentiful, draft class this year. Their eight selections (six in the first five rounds) were given an A- by NFL.com. Detroit’s seven picks (only four in the first five rounds) were given a B grade. Fans are likely to get their first taste of LAC running back Omarion Hampton, the #22 pick and second RB off the board (after Ashton Jeanty), tonight. Detroit’s first two picks, DT Tyleik Williams and G Tate Ratledge, are sitting out tonight’s game.

If starters were playing, the Lions would be sizable favorites and undoubtedly more talented. As it is, the Chargers are likely to have better players on the field, overall, and Harbaugh has a better track record as a preseason coach. I would have the Chargers favored if I was setting the line and I love the value on the LAC moneyline at +105.

I’m also betting the under which – as mentioned – has been bet up from 32.5 to 34.0. LAC’s first two preseason games last year averaged just 20.5 PPG. Detroit’s first preseason game of 2024 featured just 17 points (though they’re second and third both went over 40). I don’t expect much from the offenses tonight in everyone’s first competitive action in months.

I don’t mind whatsoever that the under is a massive fade of the public. The NFL public betting splits on Thursday morning showed a staggering 85% of O/U handle and 84% of O/U wagers on the over.