Opening Divisional Round Odds for All Games – SF/SEA, LAR/CHI, BUF/DEN
By Sascha Paruk in NFL News
Updated: January 18, 2026 at 4:04 pm ESTPublished:
- The NFC Divisional Round matchups have been set: 49ers vs Seahawks, Rams vs Bears
- The Bears are home underdogs for the second straight week
- See the opening Divisional Round odds for all games on the board
The 2026 NFL Divisional Round will take place next Saturday and Sunday (Jan. 17-18) and the first matchups have been set. The NFC #1 Seattle Seahawks will host the #6 San Francisco 49ers in an all-NFC West tilt, while the #2 Chicago Bears will welcome the #5 Los Angeles Rams to Soldier Field.
In the AFC, the #1 Denver Broncos will host the #6 Buffalo Bills, while the #2 New England will face the winner of the #5 Houston Texans at the #4 Pittsburgh Steelers, which wraps up Wild Card weekend on Monday evening.
The table below lists the opening Divisional Round odds for all cemented matchups. The final game be added after the Monday nighter.
NFL Divisional Round Odds 2026
The opening lines favor the one home team and one road team with the third game on the board opening as a pick’em.
Odds as of 7:43 pm ET at FanDuel (SF/SEA and LAR/CHI) and DraftKings (BUF/DEN). Claim the top Super Bowl betting promos for the 2026 postseason.
Odds as of Jan. 11 at DraftKings. Lock in the top NFL betting promos for the 2026 playoffs.
Seattle Opens as Big Favorite Over San Francisco
The 49ers dethroned the champion Eagles in Philadelphia on Sunday, earning a 23-19 road win as six-point underdogs. Next week, they’ll be staring down an even bigger spread, at least if the opening lines hold. The Niners are currently seven-point road underdogs at Seattle in the teams’ third meeting of the season.
San Francisco beat the Seahawks 17-13 in Seattle, but that was all the way back in Week 1. The Seahawks took a 13-3 decision in Week 18 in the Bay Area.
Bears Home Underdogs … Again
The Bears looked dead in the water when they fell behind Green Bay 21-6 in the Wild Card Round. But a furious fourth-quarter comeback by Caleb Williams and company led Chicago to a thrilling 31-28 victory as 1.5-point home underdogs.
Next weekend, they’ll host the Rams as even bigger ‘dogs, currently catching 4.5 points in the opening odds for the Divisional Round.
Bookmark SBD’s NFL odds page to see up-to-the-minute lines for every 2026 playoff game.
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Managing Editor
Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.
