#1 Michigan vs #9 Saint Louis Opening Spread, Moneyline & Total for Second Round
By Sascha Paruk in College Basketball
Published:
- The Michigan Wolverines will meet the Saint Louis Billikens on Saturday
- Both teams are coming off first-round routs
- See the opening odds for #1 Michigan vs #9 Saint Louis
The #1 Michigan Wolverines overcame a slow first half to rout #16 Howard (101-80) on Thursday night, but that performance paled in comparison to the team they’ll see in the second round. The #9 Saint Louis Billikens destroyed #8 Georgia (102-77), taking a 17-point lead into halftime and only extending their endg in the second half.
Oddsmakers are tepid on the Billikens’ chances of pulling off a second straight upset. The opening Michigan vs Saint Louis odds list the Wolverines as big chalk.
Michigan vs Saint Louis Odds
The spread has opened with Michigan as a 13.5-point favorite and -1100 on the moneyline. The Billikens are +700 underdogs to advance to the Sweet 16 in the 2026 March Madness bracket.
The game total has opened at an elevated 162.5. Both teams went way over their totals on Thursday. Michigan and Howard combined for 181 points against a total of 151.5. Saint Louis and Georgia combined for 179 points against a total of 167.5.
Odds as of March 20th at DraftKings.
The team stats highlight the disparity between the programs.
Michigan vs Saint Louis Team Stats
Michigan and Saint Louis will meet at 12:10 pm ET on Saturday morning at KeyBank Center in Buffalo, NY.
Managing Editor
Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.
