NHL Anytime Goalscorer Picks Today for Wednesday, Sept. 30

• My Wednesday NHL anytime goalscorer picks cover two intriguing matchups
• I’m honing in on goal scorers from Islanders vs Maple Leafs and Kings vs Avalanche
• See my favorite NHL anytime goalscorer picks along with analysis

Wednesday’s NHL schedule features two contests between the Islanders and Maple Leafs, along with the Kings and Avalanche. I’m looking beyond the team results for anytime goalscorer picks, where one finish can cash a bet even if that player’s team loses.

Below are my three NHL anytime goalscorer picks, with the price and reasoning behind each selection. You can compare available markets through the NHL betting apps before settling on your card.

NHL Anytime Goalscorer Odds

Odds from bet365 as of Sept. 30 for Wednesday’s games.

NHL Anytime Goalscorer Pick: William Nylander

• Pick: William Nylander anytime goalscorer (+195 at bet365)

William Nylander is my shortest-priced pick for Wednesday. Toronto’s home matchup puts an established finisher on the card, and he lit the lamp twice in Toronto’s season debut Tuesday vs Montreal.

His numbers from the 2025-26 regular season provide more useful context: 30 goals in 65 games, 156 shots on goal, and seven power-play goals. That combination points to a forward who can create scoring opportunities at even strength and on the man advantage, making +195 a reasonable starting point for a Toronto home matchup with New York. His implied probability of tickling the twine at his price is 33.9% in the NHL odds.

NHL Anytime Goalscorer Pick: Quinton Byfield

• Pick: Quinton Byfield anytime goalscorer (+300 at bet365)

Quinton Byfield offers a bigger payout than Nylander, with +300 implying a 25.0% break-even probability. His historical shooting trends support this selection, including a stretch in which he cleared 2.5 shots on goal in six of seven games while averaging 4.3 shots per game.

That trend is evidence of involvement and shot generation, not a claim that he scores in 25% of games or that a goal is likely to arrive on schedule. For a player traveling with Los Angeles to face Colorado, the appeal of +300 comes from the chance that sustained volume creates one finish at a number that pays substantially more than Nylander’s.

NHL Anytime Goalscorer Pick: Cale Makar

• Pick: Cale Makar anytime goalscorer (+375 at bet365)

Cale Makar gives this card a long-price defenseman with an established offensive role. His 2025-26 regular-season line included 20 goals in 75 games, 199 shots on goal, and four power-play goals, a profile that supports taking a look at +375 when Colorado hosts Los Angeles.

The matchup history also adds context: Makar exceeded 2.5 shots on goal in five of his last six games against the Kings, averaging 3.5 shots in those meetings.

The +375 price implies a 21.1% break-even probability. That is the lowest threshold to clear among my three picks, but one that is intriguing for the two-time Norris Trophy winner as NHL’s best blueliner (2021-22, 2024-25). A three-leg parlay with all three scoring has a cool +5500 line, meaning a $10 wager would pay out $560.