Commanders vs 49ers NFL Injury Report: Status Updates on Deebo, Diggs & More

• The 1-3-1 Commanders square off against the 5-0 49ers to cap off Week 6 on MNF
• See the injury report for this contest with updates on Deebo Samuel, Stefon Diggs and more
• Washington vs San Francisco final injury report and betting lines

When the San Francisco 49ers host the Washington Commanders at Levi’s Stadium Monday night, I am looking at a minefield of health concerns. Both squads carry major injury issues into this tilt.

The 49ers will miss wide receiver Deebo Samuel Sr (Hamstring). Meanwhile, the Commanders have already ruled out backup quarterback Marcus Mariota (Knee). High-profile targets like Stefon Diggs (Hamstring) and Mike Evans (Ribs) carry questionable designations that could swing player prop lines right up until kickoff.

I am detailing the injury statuses, practice participations, and key lineup changes for this affair. Tracking these market splits and NFL odds is the best way to handicap the matchup.

Commanders Injury Report

Key Injury Notes & Prop Market Impacts

Marcus Mariota (QB) – Out
Washington officially ruled out veteran quarterback Marcus Mariota with a knee injury. While Mariota is not the starter, he’s more important that your average QB2; Daniels is still not fully recovered from the dislocated elbow he suffered back in Week 2.

Seventh-round rookie Athan Kaliakmanis out of Rutgers will serve as Daniels’ backup on MNF.

Stefon Diggs (WR) – Questionable
Wide receiver Stefon Diggs is nursing a hamstring injury that limited his practice reps. Diggs currently sits with totals at a modest 42.5 receiving yards and 4.5 receptions. If he is hindered or sits out, expect a condensed target tree directly benefiting Terry McLaurin.

McLaurin’s receiving yard prop sits at 45.5. This is a prime spot to fire on McLaurin through your favorite NFL betting apps.

Jacory Croskey-Merritt (RB) – Out
The backfield depth takes a hit with Jacory Croskey-Merritt missing this duel due to a groin injury. His absence should solidify the ground and pound workload for Rachaad White. Bettors have already taken notice. White’s rushing yards total skyrocketed from an opening number of 21.5 up to 46.5, showing sharp money hammering the over.

49ers Injury Report

Key Injury Notes & Prop Market Impacts

Mike Evans (WR) – Questionable
Veteran wideout Mike Evans is questionable due to a ribs injury that kept him off the practice field. If he is cleared to play, he steps into an extremely favorable volume situation. San Francisco already ruled out Demarcus Robinson. In three games Robinson missed this season, Evans capitalized by averaging a robust 74 receiving yards.

The best available market sets Evans’ receiving yards prop at 63.5 (Over -112).

Deebo Samuel Sr (WR) – Out
The offense will miss one of its most dynamic playmakers, as Deebo Samuel Sr is officially out with a hamstring injury. His absence vacates a massive target share and removes his popular anytime touchdown props. Without Samuel to stretch the field horizontally, the offense will likely condense around remaining healthy targets like George Kittle.

Christian Kirk (WR) – Questionable
The receiving corps is further thinned by Christian Kirk’s questionable designation. Kirk was limited in practice while nursing a calf injury that has caused him to miss the season so far. He’s expected to suit up for the first time as a 49er.

Nick Bosa (DL) – Out
The defensive line suffers a massive blow with star edge rusher Nick Bosa ruled out. Failing to log a single practice session, his absence removes a premier pass-rushing threat. This creates a much cleaner pocket presence for Jayden Daniels, potentially giving him more time to make his passing props more appealing across the board. Monitoring NFL public betting trends here is vital to beat the closing line.