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Angels vs Guardians Odds & Picks (Sep. 14)

Robert Duff

by Robert Duff in MLB Baseball

Sep 14, 2022 · 6:34 AM PDT

Angels vs Guardians odds
Sep 13, 2022; Cleveland, Ohio, USA; Los Angeles Angels shortstop Andrew Velazquez (4) steals second base against Cleveland Guardians shortstop Amed Rosario (1) in the third inning at Progressive Field. Mandatory Credit: David Richard-USA TODAY Sports
  • The Cleveland Guardians are -120 home favorites over the Los Angeles Angels in an American League afternoon game slated for Wednesday, September 14
  • LA is 5-1 against the runline when facing Cleveland this season, while the Guardians are 8-2 ATR in the last 10 home games against the Angels
  • Get the Angels vs Guardians odds and picks, below

There’s two things you immediately notice when handicapping the series between the Cleveland Guardians (75-65, 35-30 home) and Los Angeles Angels (61-81, 30-41 away).

Firstly, there’s more streaks happening than in a badly cleaned window. Secondly, there’s also an awful lot of home cooking going on when these two ball clubs clash.

A 3-1 victory on Tuesday was extending Cleveland’s home run against Los Angeles to 10 straight victories. The Guardians are 20-1 straight up in the last 21 home games vs the Angels. LA hasn’t won a series at Cleveland since 2014.

On the other hand, in April, the Angels swept a four-game series from the Guardians.

Since 2016, Cleveland has assembled winning streaks of five, eight and 12 games against LA. Over the same time period, the Angels are showing winning runs of four and three games when facing the Guardians.

Cleveland is 8-2 agains the runline in the last 10 home games facing the Angels, and oddsmakers are staying with that formula. The Guardians are set as -120 home favorites.

Angels vs Guardians Odds

Team Moneyline Runline Total
Los Angeles Angels +100 +1.5 (+205) O 8 (+100)
Cleveland Guardians -120 -1.5 (+170) U 8 (-120)

Odds as of September 14 at BetMGM Sportsbook. Get BetMGM Sportsbook bonus code.

At moneyline odds of -120, the Guardians have an implied probability of victory of 54.55% in the MLB betting line. A successful $10 wager on Cleveland would create a payout of $18.30.


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First pitch at Progressive Field is set for 1:10 pm ET on Wednesday, September 14. The weather forecast is calling for partly cloudy skies with 10 mph wind and a temperature of 75 degrees.

In the MLB division odds, Cleveland is a -385 favorite to win the AL Central. The MLB pennant odds show Cleveland as the +2200 sixth choice to capture the AL flag. In the World Series odds,  the Guardians are at +6000.

Los Angeles Angels vs Cleveland Probable Pitchers

The 2022 season is proving to be a double-edged sword for Angels left-hander Patrick Sandoval. He’s set a career high with five wins. However, his nine losses are also a career worst.

Sandoval does share the AL lead in shutouts with one. He went 2-2 in August after going 0-5 in July.  The lefty gave up five earned runs all of last month. Twice in July, he surrendered five earned runs in a single start.

He’s served up three of his seven homers allowed this season over the past 32 innings. Sandoval beat Cleveland 4-1 on April 26, working seven shutout innings of two-hit ball en route to the victory.

In three career starts against the Guardians, Sandoval is 1-1 with a 3.14 ERA. He’s 2-5 with a 2.77 ERA in 11 road starts this season.

Sandoval vs Quantrill Stats

Patrick Sandoval
Cal Quantrill
5-9 Record 12-5
2.98 ERA 3.50
4.03 xERA 4.44
1.35 WHIP 1.22
2.47 SO/W Ratio 2.51

Guardians right-hander Cal Quantrill’s 12 wins are also a career high. He’s 20-8 over the past two seasons.

Quantrill has won eight decisions in a row. He last tasted defeat on July 5. Cleveland is 11-1 SU in Quantrill’s last 12 starts.

Quantrill has allowed two earned runs or fewer in six of his past seven starts. He’s in the bottom 9% of MLB pitchers in exit velocity at 114.9.

On April 28, Quantrill took a 4-1 loss against the Angels. He allowed three runs in four innings, but just one was earned. In three career appearances, including two starts, Quantrill is 1-1 with a 1.29 ERA and 1.00 WHIP when facing the Angels.

Batting Average vs Starting Pitchers

Guardians Batters Batting Average vs Sandoval Angels Batters Batting Average vs Quantrill
Owen Miller .333 Joe Adell .200
Jose Ramirez .200 David Fletcher .333
Amed Rosario .200 Shohei Ohtani .500
Myles Straw .250 Taylor Ward .333

Cleveland’s Owen Miller is 1-for-3 (.333) when facing Sandoval. Myles Straw is 1-for-4 (.250). Both Amed Rosario and Jose Ramirez are 1-for-5 (.200). Ramirez has driven in a run.

For the Angels, Shohei Ohtani is 1-for-2 (.500) when batting against Quantrill. David Fletcher and Taylor Ward are each 1-for-3 (.333). Ward also has an RBI. Jo Adell is 1-for-5 (.200).

Angels vs Guardians Prediction

The home team has covered against the runline in 16 of the past 20 Angels vs Guardians games. On Tuesday, Cleveland halted the home run streak of Angels outfielder Mike Trout at seven games.

Overall, Cleveland is 5-0 SU in the past five games and 7-1 SU through the past eight games. Before making a bet on today’s game check out the new Barstool Sportsbook promo code offer to get the latest deal, including a 1k risk-free bet.

Pick: Cleveland Guardians ML (-120)


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