Best MLB Home Run Odds & Picks Today: August 19 Slate

• A 15-game MLB slate offers high-leverage power spots, from Coors Field to Great American Ball Park.
• We break down the top MLB home run props, balancing season-long power with ballpark factors.
• Shohei Ohtani leads the board, while several longshots offer intriguing value tonight.

HR Props: Top Home Run Picks Across Today’s MLB Slate

With a full 15-game MLB slate on August 19, bettors have a deep board of matchups to target. Reviewing the latest MLB odds, the best home run opportunities come from pairing elite power bats with favorable hitting environments.

Today’s slate features several hitter-friendly venues, including Wrigley Field, Daikin Park, Coors Field, and Great American Ball Park. Recent MLB park factors help narrow the board, with Shohei Ohtani standing out as our top pick and Yordan Alvarez highlighting the longshot tier.

Home Run Picks Today

Odds are sourced from BetMGM, Caesars, bet365, and the ScoreBet, representing the best available market prices.

Munetaka Murakami (+430) — Chicago White Sox vs. Chicago Cubs

The Chicago White Sox travel to Wrigley Field to battle the Chicago Cubs and probable starter Clay Holmes. Wrigley Field currently ranks ninth in the league in overall run production, averaging 9.44 runs per game.

Furthermore, the friendly confines are surrendering 2.89 home runs per game this season. Murakami’s volume metrics make him a compelling longshot in this environment. Pairing his natural power profile with a stadium that consistently rewards fly balls provides bettors with a distinct tactical edge tonight.

Salvador Perez (+420) — Kansas City Royals vs. Athletics

Salvador Perez and the Kansas City Royals host the Athletics at Kauffman Stadium. This venue has quietly served as a strong offensive environment this season, ranking seventh overall with 9.61 runs per game while yielding 2.26 home runs per contest.

The veteran catcher continues to display an underdog mentality at the plate, consistently producing hard contact. In a ballpark heavily tilted toward offensive production, Perez’s knack for high-leverage power swings makes him an excellent value.

Elly De La Cruz (+291) — Cincinnati Reds vs. St. Louis Cardinals

Elly De La Cruz will face St. Louis Cardinals probable starter Matthew Liberatore at Great American Ball Park. While Great American Ball Park is traditionally known to favor hitters, it ranks 21st in runs per game this season at 8.48. However, it still provides a steady 2.61 home runs per game.

De La Cruz possesses a formidable combination of bat speed and raw power. When you combine his elite exit velocities with a stadium built for home runs, he remains a high-ceiling target against vulnerable pitching.

Yordan Alvarez (+285) — Houston Astros vs. Los Angeles Angels

The Houston Astros welcome the Los Angeles Angels and probable starter Walbert Ureña to Daikin Park. The stadium currently ranks 10th in the league in runs scored per game at 9.27. It has also seen 2.79 home runs per game, making it an above-average venue for targeting power bats.

Alvarez is a premier slugger whose disciplined approach consistently yields hard-hit balls. Taking advantage of this generous Houston environment gives him a phenomenal floor for clearing the outfield fences tonight.

Kyle Schwarber (+220) — Philadelphia Phillies vs. Miami Marlins

Kyle Schwarber and the Philadelphia Phillies host the Miami Marlins and probable pitcher Sandy Alcantara at Citizens Bank Park. This ballpark is playing extremely well for hitters, ranking eighth in runs per game at 9.58 while surrendering 2.56 home runs per contest.

Schwarber is known for his tremendous work ethic and brute strength, and thrives in these hitter-friendly conditions. His consistent launch angle and volume of deep fly balls make him a top-tier candidate to exploit a favorable home environment.

Shohei Ohtani (+215) — Los Angeles Dodgers vs. Colorado Rockies

Shohei Ohtani will dig in against Colorado Rockies probable starter Kyle Freeland at Coors Field. The thin air in Denver continues to provide one of the most extreme offensive environments in baseball. Coors Field ranks fourth in runs per game at 11.46 and is seeing an elevated 2.70 home runs per game.

Ohtani’s unparalleled power profile perfectly aligns with Denver’s altitude. Facing a pitch-to-contact arm in a stadium that turns deep flies into massive home runs creates a near-perfect storm for the Dodgers’ superstar.