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White Sox vs Guardians Picks and Odds (April 18)

Chris Amberley

by Chris Amberley in MLB Baseball

Apr 17, 2022 · 7:07 PM PDT

Jose Ramirez slaps a triple
Cleveland Guardians' Jose Ramirez hits a two-RBI triple during the third inning of a baseball game against the Cincinnati Reds in Cincinnati, Tuesday, April 12, 2022. (AP Photo/Aaron Doster)
  • The White Sox vs Guardians odds favor Cleveland as -115 moneyline favorites on Monday (April 18, 6:10pm ET)
  • Chicago will give the ball to Dallas Keuchel (1-0, 5.40 ERA), while Cleveland will counter with Triston McKenzie (0-1, 2.57 ERA)
  • Read below for the White Sox vs Guardians odds, analysis and betting prediction

AL Central rivals clash for the first time this season on Monday (April 18) as Cleveland hosts Chicago. The Guardians are fresh off getting swept at home by San Francisco, while the White Sox took two of three from the Rays over the weekend.

Chicago enters play with a division best 6-3 record, but it’s the hometown Guardians who have the shorter moneyline odds for this contest.

White Sox vs Guardians Odds

Team Moneyline Runline Total
Chicago White Sox -105 -1.5 (+155) O 8 (-110)
Cleveland Guardians -115 +1.5 (-180) U 8 (-110)

Odds as of April 17th at Caesars Sportsbook.

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Cleveland opened as a -115 moneyline favorites, in a contest that features a total of 8 runs. First pitch is scheduled for 6:10 pm ET at Progressive Field in Cleveland, Ohio, with rainy 40 degree temperatures currently in the forecast.

Probable Pitchers

Chicago, a top-four contender in the World Series odds, will send left-hander Dallas Keuchel to the hill. Keuchel is coming off the worst statistical season of his career in 2021, posting career-worsts in ERA and opponent batting average, while allowing the most home runs (25) since he entered the big leagues.

The 34-year-old didn’t look particularly sharp in his season debut, although he did pick up the win. He surrendered six hits and three runs over 5 innings against Seattle, but was the benefactor of six runs of support from his lineup. One positive for Keuchel was his control. He stuck out five and didn’t allow a walk, throwing 53 of his 80 pitches for strikes.

Keuchel is 4-2 lifetime against Cleveland with a 3.53 ERA in 11 career starts. He’s undefeated at Progressive Field winning both of his decisions, while allowing only nine runs over 34 innings.

Keuchel vs McKenzie Stats

Dallas Keuchel
Triston McKenzie
1-0 Record 0-1
5.40 ERA 2.57
1.20 WHIP 1.00
.286 OBA .217
5.0 SO/W Ratio 3.5

Cleveland, who projects to finish second in the AL Central behind Chicago in the MLB win totals, will counter with Triston McKenzie. The 24-year-old has made two appearances this season, coming out of the bullpen in the Guardians opener, and then starting last Wednesday against the Reds.

McKenzie was sharp versus Cincy, yielding three hits and no runs over 4 innings, while striking out six. McKenzie has made five career starts against the White Sox and the results have not been pretty. He’s allowed 22 runs over 17.2 innings, while posting an 0-2 record.

Chicago vs Cleveland Betting Analysis

Both of these teams enter play ranked above average in runs per game although you’d never know it from their recent performances. The Guardians scored just four times during a three-game set versus the Giants, averaging only 5.6 hits per outing.

Jose Ramirez and Oscar Mercado are off to fantastic starts with three home runs each, while Ramirez and Owen Miller are both hitting north of .450.

The White Sox meanwhile, have scored three or fewer runs in five of their past six which is quite underwhelming considering they feature four players listed in the AL MVP odds.

Tim Anderson has been the club’s best hitter to date, batting .393 with 11 runs scored in only seven games. 24-year-old Andrew Vaughan is one of the few bats that has shown any pop, leading the team in RBI (6), and sharing the team lead in home runs (2).

White Sox vs Guardians Last 10 Meetings

Date Away Team Home Team Score
9/26/21 White Sox Guardians CHW, 5-2
9/25/21 White Sox Guardians CLE, 6-0
9/24/21 White Sox Guardians CHW, 1-0
9/23/21 White Sox Guardians CLE, 5-3 F/7
9/23/21 White Sox Guardians CHW, 7-2 F/7
8/1/21 Guardians White Sox CHW, 2-1
7/31/21 Guardians White Sox CLE, 12-11
7/30/21 Guardians White Sox CHW, 6-4
6/1/21 White Sox Guardians CLE, 6-5
5/31/21 White Sox Guardians CLE, 3-1 F/7

 White Sox vs Guardians Pick

The recent offensive struggles for both teams could continue on Monday with cold, rainy conditions in the forecast. Five of the past six matchups between these two clubs have failed to exceed eight runs, while the Guardians have really struggled against left-handed pitching.

Cleveland is batting just .234 with a .359 slugging percentage versus southpaws so far, compared to .295 with a .505 slugging percentage versus righties. The Guardians faced a pair of lefties over the weekend in Mike Wood and Carlos Rodon, and managed only one run and six hits over 16 innings.

Pick: Chicago White Sox Moneyline (-105), Under 8 (-110)

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