Inter Milan vs Benfica Prediction, Odds, Lineups – Champions League Quarterfinals Leg 2

• Inter Milan and Benfica clash in the second leg of the Champions League Quarterfinals Wednesday
• The Serie A outfit won last week’s tie 2-0
• Continue reading for the Inter Milan vs Benfica prediction, odds and lineups

Benfica faces an uphill battle in order to progress in Europe’s most prized competition as they travel to the San Siro to lock horns with Inter Milan on Wednesday. The kick-off for this Champions League Quarterfinals second leg is scheduled for 3 PM ET and we have your Inter Milan vs Benfica prediction here.

Inter grabbed a massive 2-0 victory in Portugal last week, giving them a notable advantage when it comes to going on to the semifinals. However, they’re fresh off a shock defeat in league action over the weekend, but we’ll get into that more below.

Inter Milan vs Benfica Odds

Inter is the favorite here with +110 Champions League odds for an implied win probability of 47.62%. Benfica comes back at +255 and has a 28.17% of coming out victorious.

Odds as of April 18th at DraftKings.

How to Watch Inter Milan vs Benfica

This match kicks off at 3:00 pm EST and can be seen on Paramount+ in the United States. In Canada, the match will stream on DAZN.

Inter Milan vs Benfica Preview

The Nerazzurri are on the verge of their first semifinal since the 2009-2010 campaign, where Inter actually ended up winning the Champions League, beating Bayern Munich in the grand finale.

While Simone Inzaghi’s men have struggled to find success in Serie A this term, they certainly have a legitimate chance to get their hands on another UCL trophy. Nico Barella and Romelu Lukaku were on target in last week’s win at Benfica, with Barella heading home before his Belgian teammate scored from the spot to seal the deal.

That being said, Inter just lost 1-0 on Saturday to AC Monza Brianz, a team 13 points behind them in the table. In fact, they’ve failed to win in six games in Italy. Not exactly a good sign, but Inzaghi’s group only needs a draw here to move on. Even a slim defeat would do.

Benfica couldn’t be in worse form for such an important fixture. The Eagles have lost three consecutive outings in Portugal, now just holding a four-point lead at the top. Their attack has also scored only once in the previous three games across competitions.

Touchdown! 🇮🇹#UCL • #FCIMSLB pic.twitter.com/xSbSNn5Gj3

— SL Benfica (@slbenfica_en) April 18, 2023

The quarterfinals have unfortunately been Benfica’s kryptonite, failing to ever move on to the last four. They also lost at this stage in 2021-22 to Premier League giants Liverpool. On a more positive note, Roger Schmidt’s squad has already won in Italy in this year’s competition, beating Juventus in the group stages. It will take a lopsided victory to eliminate Inter on Wednesday.

Inter Milan vs Benfica History

Prior to leg one in this year’s tournament, these teams had only met on three other occasions in the Inter Milan vs Benfica history. Two of those matches ended 0-0, and one ended in a 4-3 Inter Milan win. These matches all came long ago though back in 2008 and 2004.

Inter Milan vs Benfica Projected Lineups & Injuries

Inter Projected Lineup: Onana; Darmian, Acerbi, Bastoni; Dumfries, Barella, Mkhitaryan, Brozovic, Dimarco; Dzeko, Martinez

Injuries & absences: Skriniar, de Vrij

Benfica  Projected Lineup: Vlachodimos; Gilberto, A. Silva, Otamendi, Grimaldo; Florentino, Aursnes; Neres, R. Silva, Mario; Ramos

Injuries & absences: Ristic, Draxler

Inter is missing a pair of key players in Milan Skriniar and Stefan de Vrij. Lukaku will likely come on as a substitute again, looking for his 10th UCL goal in an Inter shirt. For Benfica, veteran center-back Nicolas Otamendi returns after serving a ban in the opening leg.

Inter vs Benfica UCL Stats

Inter Milan vs Benfica Prediction

It’s hard to back Benfica when they’re playing so poorly at the moment. I expect Inter to win this one and march into the semifinals for my Inter Milan vs Benfica prediction.

Inter Milan vs Benfica Picks: Inter +110