Nebraska vs Vanderbilt Picks, Props, and How to Watch

• Vanderbilt’s 12-5 record against Top-50 opponents makes them my moneyline pick
• Tyler Tanner and Pryce Sandfort’s offensive efficiency drives my over total bet
• Betting splits and situational trends reveal the most profitable angles for this matchup

How to Watch Nebraska vs Vanderbilt

The #4 Nebraska Cornhuskers (27-6 SU, 18-14-1 ATS) square off against the #5 Vanderbilt Commodores (27-8 SU, 18-17 ATS) in a second-round clash on March 21 at 8:45 pm ET, broadcast live on TNT from the neutral floor of the Paycom Center in Oklahoma City. Nebraska enters this single-elimination tournament environment as a slight underdog after securing the program’s first-ever NCAA Tournament victory.

Below, I set out my data-driven Nebraska vs Vanderbilt picks and predictions, plus the latest odds and betting splits.

Nebraska vs Vanderbilt Picks & Predictions

Best Bet: Over 146.5 Total Points (-110 at BetMGM)

Expect both offenses to operate at a high pace. With high-ceiling scorers and efficient complementary pieces – like Vanderbilt’s Devin McGlockton, who shot a perfect 6-for-6 from the field in his last outing – this matchup sets up beautifully for a shootout.

KenPom projects a 149-point total (75-74 Vandy) and, even with the increased defensive intensity that comes with elimination games, that’s a solid cushion for the over.

NEB vs VAN Team Stats

Vanderbilt holds a distinct situational advantage when stepping up in class. The team thrives against elite competition, boasting a highly profitable 12-5 outright record (70.5% win rate) against Top-50 ranked opponents this season. Conversely, Nebraska has inflated its impressive win total against weaker programs, heavily struggling in step-up spots with a 3-5 record (37.5% win rate) against the Top 50. Vanderbilt’s proven ability to execute against high-level opponents heavily supports my primary side pick

Vanderbilt holds a distinct situational advantage when stepping up in class. The team thrives against elite competition, boasting a highly profitable 12-5 outright record (70.5% win rate) against Top-50 ranked opponents this season. Conversely, Nebraska has inflated its impressive win total against weaker programs, heavily struggling in step-up spots with a 3-5 record (37.5% win rate) against the Top 50.

Nebraska vs Vanderbilt Odds (Spread, Moneyline & Total)

Prediction Markets

NEB vs VAN Odds

Learn more about Prediction Markets

Kalshi

Vanderbilt ML

54%

Neb +2.5

53%

Under 147.5

52%

Over 147.5

49%

Vandy -2.5

48%

Nebraska ML

47%

Predict

The current betting market paints the picture of an incredibly tight battle, positioning Vanderbilt as slight 2.5-point favorites. On the moneyline, the best price on Vandy is 54¢ at Kalshi (equal to a -117 odds). The best Nebraska price is also at Kalshi (47¢ or +113 odds). The game total ranges from 146.5 to 147.5. BetMGM has the best number for over bettors while Kalshi has the best number for under bettors.

Placing a $100 wager on the favored Vanderbilt moneyline at -117 yields an $85 profit, resulting in a total payout of $185.

Putting that same $100 on the underdog Nebraska moneyline at +113 yields a $113 profit for a total payout of $213 if the Huskers secure the victory.

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Nebraska vs Vanderbilt Betting Splits

As of midday on March 21, the college basketball public betting splits reveal some distinct, unified opinions from the public.

In the moneyline market, the consensus is firmly in Vanderbilt’s corner. Vanderbilt draws 64.39% of the betting tickets and an even stronger 64.76% of the total stake. Nebraska garners just 35.61% of the tickets and a mere 35.24% of the money.

If the side markets show confidence, the totals market shows absolute conviction. Based on the betting splits, the market anticipates the high-scoring shootout I projected earlier. A massive 85.11% of the betting tickets are on the over, backed by an overwhelming 88.96% of the total money. Fading the scoring requires taking a lonely position, with the under drawing just 11.04% of the overall stake.