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Picks, Predictions & How to Watch Tigers vs Orioles on May 22

Chris Amberley

By Chris Amberley in MLB Baseball

Published:


The Orioles celebrate a run versus the Nationals in an Interleague matchup.
May 17, 2026; Washington, District of Columbia, USA; Baltimore Orioles shortstop Gunnar Henderson (2) celebrates with Orioles right fielder Tyler O'Neill (9) after hitting a solo home run against the Washington Nationals during the first inning at Nationals Park. Mandatory Credit: Geoff Burke-Imagn Images
  • The Orioles are -138 moneyline favorites tonight versus the Tigers
  • Seven of Detroit’s last 10 games have eclipsed the total
  • See the top picks, predictions and how to watch Tigers vs Orioles on May 22, below

The Baltimore Orioles host the Detroit Tigers tonight in the opening contest of a 3-game set. Baltimore enters this matchup at 21-29, and is listed as -138 moneyline favorites in the MLB odds. Detroit sits at 20-30, and enters play stuck in a six-game losing streak.

Chris Bassitt will toe the rubber for Baltimore, while Jack Flaherty counters for Detroit. Neither pitcher has performed well so far this season, setting the stage for a high-scoring affair.

Below, you’ll see the top picks, predictions and how to watch the Tigers vs Orioles contest on May 22nd.

Orioles vs Tigers Picks

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My two favorite bets tonight are the Orioles moneyline and Over 8.5 runs. Flaherty enters with an elevated 5.77 ERA, while Bassitt’s 6.08 ERA is even worse.

I predict Baltimore will out-slug the visitors to defend their home turf. With the total set at 8.5 runs, taking the Over holds strong value. Both starters are susceptible to giving up crooked numbers, and the Over has cashed in 7 of the Tigers’ last 10 games. Additionally, unders are 7-3 in the Orioles’ recent contests, creating a contrarian spot for an offensive breakout.

Chris Bassitt vs Jack Flaherty Stats

StatisticChris Bassitt (BAL)Jack Flaherty (DET)
Win-Loss Record2-30-5
ERA6.085.77
WHIP1.841.60
FIP4.745.03
K/95.849.89
BB/94.385.98
Opponent BA.327.246
IP per Start4.64.4

Flaherty brings significant swing-and-miss stuff to the mound, boasting a 9.9 K/9 rate. However, control issues remain his undoing. Walking nearly six batters per nine innings constantly puts him in high-leverage situations, inflating his ERA to 5.77. His inability to locate the strike zone is why he is still searching for his first victory at 0-5.

Bassitt pitches much more to contact, generating a pedestrian 5.8 K/9. Unfortunately for Baltimore, opponents are making loud contact. He allows a .327 batting average, culminating in an elevated 1.84 WHIP. While his 4.74 FIP suggests some unfortunate batted-ball variance, putting traffic on the base paths limits his ability to pitch deep into games. Neither starter typically lasts through the fifth inning, so expect both bullpens to be heavily involved.

Tigers vs Orioles Stats

StatisticBaltimore (Home)Detroit (Away)
Overall Record21-29 [24th]20-31 [T-27th]
Runs / Game4.62 [14th]3.77 [27th]
Batting Average.245 [13th].235 [17th]
OPS.734 [13th].694 [14th]
Avg. Exit Velocity88.8 mph [T-12th]87.8 mph [T-22nd]
Stolen Bases / Game0.50 [T-21st]0.31 [28th]
Team ERA4.99 [21st]3.96 [T-8th]
Team WHIP1.46 [21st]1.28 [T-8th]

Several distinct mismatches dictate the flow of this game per the numbers in the MLB starting lineups. Offensively, Baltimore holds a significant advantage at Camden Yards. They rank in the top half of the league in home run production, averaging 4.62 runs per game on their own turf. Conversely, Detroit struggles mightily to produce on the road, ranking 27th with a meager 3.77 runs per game away from Comerica Park.

Baltimore also holds the edge in quality of contact. Their lineup averages a solid 88.8 mph exit velocity at home, dwarfing Detroit’s 87.8 mph mark on the road.

Neither club poses a threat to manufacture free bases via the steal. Baltimore averages just 0.50 stolen bases per game at home, while Detroit swipes a mere 0.31 bags on the road. Because neither team relies on stolen bases, stringing together consecutive hits is paramount.

Tigers vs Orioles Odds

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Tigers vs Orioles Predictions

  • Chris Bassitt Under 4.5 Strikeouts (-102 at Bet365)
  • Gunnar Henderson to hit a home run (+340 at Bet365)
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Moving over to the MLB Props market, where the most glaring edge tonight is on the mound. Bassitt’s strikeout line sits at 4.5. The veteran right-hander averages 6.28 strikeouts per nine innings while lasting just 4.6 innings per start. Mathematically, that projects him for roughly three punchouts tonight. Bassitt has struggled throughout his career versus the hitters in the Detroit lineup per the MLB batter vs pitcher stats, yielding a .560 slugging percentage and .835 OPS over 50 at-bats.

For offensive targets, Gunnar Henderson is primed to inflict damage. He has 10 home runs this season, maintaining an 89.8 mph average exit velocity. Squaring off against a vulnerable Flaherty, backing Gunnar Henderson to go yard provides tremendous upside.

How to Watch Tigers vs Orioles

First pitch for the Tigers vs Orioles matchup is set for 7:15 pm ET at Oriole Park at Camden Yards, in Baltimore, MD. Regional networks will provide the broadcast coverage, while the MLB weather data is calling for chilly, 55 degree game-time temperatures.

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Chris Amberley
Chris Amberley

Sports Writer

As SBD's resident Swiss Army Knife, Chris covers virtually every sport including NFL, PGA, NBA, MLB, NCAAB, NCAAF and the Olympics. A true grinder, he'd rather pick off small edges in the player props market than swing for the fences with a 5-leg parlay.

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