Champions League Picks Today – Predictions for All 9 Games on Nov 4

• Back Real Madrid vs AEK Athens Over 3.5 goals (-117) in Wednesday’s Champions League action
• Take Liverpool (-178) and Manchester City (-170) on the moneyline in our Champions League predictions
• Get all nine Champions League picks and betting predictions for Wednesday, Nov. 4

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Matchday 4 in the UEFA Champions League wraps up with nine more games on Wednesday, Nov. 4. The action begins at 12:45 pm ET, with Real Madrid and Liverpool heading on the road as sizable favorites against AEK Athens and Fenerbahce, respectively. Seven more games kick off at 3:00 pm ET, including intriguing matchups between RB Leipzig and Manchester City and Slavia Prague and Arsenal.

With nine games on the schedule, there are plenty of betting angles to consider. Below, I break down my top pick for each matchup and highlight the best available odds.

Champions League Odds for Nov 4

Odds from theScore Bet. All other odds in table from BetMGM.

Prediction markets like Kalshi and Novig often offer better prices than traditional sportsbooks, but they are not available in every state, including Michigan, Nevada, and Ohio. If you cannot access either platform, you can use the BetMGM promo code or theScore Bet promo code to claim a welcome bonus.

Looking for longer-term betting opportunities? Check out our UEFA Champions League futures odds.

Best Champions League Picks Today (Nov 4)

Best Odds” as of 7:38 pm ET, Nov. 3. Lines are subject to change. Claim SBD’s exclusive Kalshi promo code if you live in a region where prediction markets operate.

AEK Athens vs Real Madrid Pick

Pick: Over 3.5 goals (-117, Kalshi). Real Madrid has scored 10 goals in its first three matches, putting 25 of 43 shots on target. AEK, meanwhile, has conceded eight goals over the same span. Madrid’s potent attack and AEK’s defensive struggles make the over appealing, although bettors need at least four goals to cash this ticket.

Fenerbahce vs Liverpool Pick

Pick: Liverpool moneyline (-178, Kalshi). Liverpool has been one of the more productive attacking teams in the competition, scoring 12 goals and putting 24 of 56 shots on target through three matches. Fenerbahce has conceded nine goals and carries a -6 goal difference. The hosts’ defensive problems give Liverpool a favorable matchup, making the visitors the stronger side despite playing in a challenging Istanbul environment.

Borussia Dortmund vs Betis Pick

Pick: Draw (+335, Kalshi). Betis has scored seven goals through three matches, compared with five for Dortmund, while both teams have conceded four. Dortmund has the home advantage, and Serhou Guirassy’s four goals make the hosts a threat. However, Betis has shown greater attacking production, setting up an intriguing matchup. Dortmund will also be without Emre Can and Justin Lerma, while Cucho Hernandez and Junior Firpo are unavailable for Betis. The draw is a high-variance selection rather than a conservative bet, but the available price makes it worth considering.

Porto vs Napoli Pick

Pick: Porto moneyline (+100, Kalshi). This matchup looks evenly balanced, with Porto getting the nod because of its home advantage. Neither team has been particularly convincing defensively: Porto has scored two goals and conceded six through three matches, while Napoli has scored five and allowed seven. Those numbers make this a difficult game to call, so Porto is a low-confidence home selection rather than a bet to approach with strong conviction.

PSV Eindhoven vs Club Brugge Pick

Pick: Club Brugge moneyline (+223, Kalshi). Club Brugge has been considerably more productive in attack, scoring nine goals and recording 19 shots on target in three matches. PSV has managed just two goals and 10 shots on target. Although PSV has conceded only twice, its injury situation is concerning. Jerdy Schouten, Kiliann Sildillia, Sami Ouaissa, and Alassane Plea are listed as out, while Paul Wanner and Sam Lammers are doubtful. Club Brugge has just one listed absence, Joel Ordonez. Given the visitors’ superior attacking numbers and healthier squad, the +223 price offers an interesting underdog opportunity, although PSV’s defensive record remains a reason for caution.

RB Leipzig vs Manchester City Pick

Pick: Manchester City moneyline (-170, Kalshi). Manchester City has scored nine goals and recorded 24 shots on target through three matches, while averaging 57.33% possession. Leipzig, by comparison, has scored just three goals and conceded eight. City’s superior attacking production and ability to control possession make the visitors the more appealing side at this price.

Lens vs Como Pick

Pick: Como 1907 moneyline (+122, Kalshi). Como has made a strong start offensively, scoring 10 goals and putting 24 of 36 shots on target through three matches. Lens has managed just three goals while conceding seven. The visitors have been considerably more productive in front of goal, making Como an attractive plus-money option against a team that has struggled defensively.

Slavia Prague vs Arsenal Pick

Pick: Under 3.5 goals (-156, Novig). Arsenal has conceded just two goals through three matches and has averaged 56.67% possession. Slavia, meanwhile, has a -3 goal difference. Arsenal’s defensive solidity and ability to control possession support the under, although the -156 price offers limited betting value.

Viking vs Sabah Pick

Pick: Viking moneyline (-238, Novig). Viking has scored five goals through three matches, compared with three for Sabah. Viking’s attacking advantage and home-field edge make the hosts worth considering, but their defensive vulnerabilities and the relatively expensive moneyline leave little margin for error.