UFC 334 Main Card Predictions: Gane vs Hokit Odds & Picks

• UFC 334 takes over Madison Square Garden on Saturday, November 14 with Ciryl Gane vs Josh Hokit on top
• My card runs three moneylines, one method play and one round total
• See my UFC 334 main card predictions, picks and odds below

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UFC 334 lands at Madison Square Garden on Saturday, November 14. Early prelims start at 5 pm ET, the prelims follow at 7 pm ET, and the main card begins at 9 pm ET on Paramount+.

I have five selections on this board, headlined by the heavyweight title fight between Gane and Hokit. Here are my UFC 334 main card predictions and odds.

UFC 334 Main Card Predictions & Odds

BetMGM has Gane at -200 and Hokit at +165 in the main event. Hasan is the biggest price on the board at -1250, with Gurule coming back at +725.

The middle three fights on the main card are all near pick-’em odds, giving bettors value on either side.

BetMGM odds as of Saturday, November 14 at 12:14 AM ET. The Gane price includes disqualification; my prediction is a knockout or TKO. The round total is from bet365’s November 10 board. Prices are subject to change. Browse the best UFC betting apps for UFC 334.

Gane vs Hokit Prediction

• Gane vs Hokit Pick: Ciryl Gane by KO/TKO (+100 by KO/TKO or DQ at BetMGM)

Hokit’s wrestling is clearly an issue for the champion. Gane has struggled badly in all three fights where he was taken down, including his two losses to Francis Ngannou and Jon Jones, and that is the obvious route to an upset. Hokit averages an imposing 3.73 takedowns per 15 minutes, even if he has just three takedowns in his four UFC fights.

But as much as grappling favors Hokit on paper, Gane’s size could be an issue for him. Although he weighed in just 11.2 pounds heavier, Gane owns a huge three-inch height and eight-inch reach advantage over the smaller American. Perhaps most importantly, he is the first fighter Hokit will face who can match his speed and athleticism.

The last time Hokit faced a legitimate full-sized heavyweight, he chose to strike with Curtis Blaydes, resulted in the clear 2026 Fight of the Year. As exciting as that was, he will not have that type of success against Gane on the feet.

Harrison vs Nunes Prediction

• Harrison vs Nunes Pick: Amanda Nunes ML (+140 at BetMGM)

Both women are coming off super long layoffs, especially Nunes, who has been retired since June 2023. That makes this a difficult fight to handicap.

Despite the time gap, Harrison’s layoff is the one that concerns me more due to the neck surgery that caused this fight’s postponement. Neck injuries are detrimental to any athlete, much less a 36-year-old grappler who continues to make a near-life-threatening cut down to 135 pounds.

While Harrison is easily the best grappler Nunes will face, it is still a style the Brazilian has done well against. Nunes’ 82 percent takedown defense has prevented her from ever being taken down more than twice in a single UFC fight. She has landed 34 takedowns in her last 15 appearances while being floored just three times in that span. If Harrison cannot secure takedowns, Nunes owns a significant striking advantage.

While there are an abundance of questions on either side of this matchup, Harrison’s neck injury and weight cut are bound to catch up with her at some point. It would not be surprising if the greatest female fighter of all time was the one who exposed it.

Borralho vs Belgaroui Prediction

• Borralho vs Belgaroui Pick: Caio Borralho ML (-167 at BetMGM)

Belgaroui is gigantic for middleweight — he will be five inches taller than Caio Borralho — and he is turning around just two months after his last win. That time frame can be concerning for someone his size, but it took almost no effort for him to dismantle Djorden Santos in September.

The Alex Pereira prototype has significantly improved his grappling, but it was not long ago that Marco Tulio out-grappled him to a victory and Taiga Iwasaki’s pressure gave him trouble on DWCS. He has been taken down seven times since then, but only controlled for a total of 5:25.

With just one takedown in his last five fights, it is easy to forget how dominant Borralho was with his grappling during his early UFC tenure. He is a good striker, but he initially made an impression with his wrestling, racking up 25 minutes of control across his first three UFC fights. If he can secure Belgaroui, a Brazilian jiu-jitsu blue belt, down on the canvas, he will own a massive grappling advantage.

This is a dangerous fight for Borralho, but the Fighting Nerds captain has a golden opportunity to remind fans how well-rounded and high-level his game is.

Medic vs Holland Prediction

• Medic vs Holland Pick: Kevin Holland ML (+140 at BetMGM)

Uros Medic rides a four-fight win streak into this main card fight, but his style has not changed since his UFC debut. Medic’s Gung-Ho style allows him to beat anyone just as much as he could lose, and he has benefited from favorable matchups lately against past-their-prime fighters.

Holland can be just as volatile at times, but his durability is undeniable. He has only been knocked down twice in 29 UFC fights, and his only two KO losses were corner stoppages due to broken bones.

Medic always throws caution to the wind, but he will have to overcome Holland’s sizeable 10-inch reach advantage to land one of his signature bombs and continue his knockout streak. Holland also has grappling in his back pocket, though nobody expects him to use it.

In the biggest coin-flip fight of the night, Holland’s durability, length and underrated grappling could be the difference in stopping the red-hot Medic.

Hasan vs Gurule Prediction

• Hasan vs Gurule Pick: Over 1.5 Rounds (+135 at bet365 on Nov. 10)

Everyone expects a quick night for Bilal Hasan after back-to-back show-stopping knockouts in the Octagon, and his sophomore matchup against Luis Gurule’s 1-4 UFC record heightens that narrative.

Hasan has gone the distance only once, but his last fight was two seconds away from hitting Over 1.5.

Still, Gurule, who has been knocked out in the UFC before, could be a tougher matchup for Hasan than initially perceived. Gurule is a very solid boxer coming from a smart camp that is currently thriving in the Octagon. Aside from his knockout loss to Ode’ Osbourne, he has been difficult to hit at times. I expect him to stay patient, stay defensively sound and make Hasan work, which is where the over comes in.

Hasan’s movement and deadly kicking game should still give him the edge, but this fight might not be the immediate blowout that it was made to be on paper.