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MLB NRFI Picks & Odds, Plus First 5 Innings Best Bets for Wednesday (June 22)

Sascha Paruk

by Sascha Paruk in MLB Baseball

Jun 21, 2022 · 9:55 PM PDT

Arizona Diamondbacks pitcher Madison Bumgarner throwing a pitch
Jun 17, 2022; Phoenix, Arizona, USA; Arizona Diamondbacks pitcher Madison Bumgarner throws in the fourth inning against the Minnesota Twins at Chase Field. Mandatory Credit: Mark J. Rebilas-USA TODAY Sports
  • The MLB has a full 15-game slate on Wednesday, June 22, 2022
  • See the NRFI and YRFI odds plus first 5 innings moneyline odds
  • Get NRFI picks and first-half best bets for Wednesday

The MLB schedule for Wednesday, June 22, see all 30 teams in action. Sportsbooks have posted game props for the majority of the matchups, including 1st inning over/unders and first 5 innings moneyline props.

The first section below lists the NRFI odds (no runs 1st inning) and YRFI odds (yes runs 1st inning) available as of Tuesday night. The second section focuses on first 5 innings moneyline odds and picks.

MLB NRFI Odds (June 22)

Mets vs Astros -104 -122
Blue Jays vs White Sox +100 -128
Phillies vs Rangers -118 -108
Diamondbacks vs Padres -122 -104
Rockies vs Marlins -130 +102
Dodgers vs Reds -104 -122
Cubs vs Pirates TBD TBD
Nationals vs Orioles -111 -115
Tigers vs Red Sox -115 -111
Yankees vs Rays +114 -146
Giants vs Braves -122 -104
Guardians vs Twins -113 -113
Cardinals vs Brewers -106 -120
Mariners vs Athletics TBD TBD
Royals vs Angels TBD TBD

Odds as of June 21 at FanDuel Sportsbook. See available FanDuel Sportsbook promo codes


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The only NRFI odds not on the board yet are Phillies vs Rangers, Cubs vs Pirates, Mariners vs Athletics, and Royals vs Angels. Check your local sportsbook closer to first pitch.

Diamondbacks vs Padres YRFI Pick

My pick of the day here is at least one run in the first inning between the Arizona Diamondbacks and San Diego Padres (4:10 pm ET). The pitching matchup sees Madison Bumgarner up against Mike Clevinger and, if this was 2018, that would have boded well for a NRFI bet.

But it’s 2022 and these pitchers are not the top-tier arms they used to be.

Bumgarner’s ERA is decent, overall, sitting at 3.45 entering play on Wednesday. But his WHIP is a massively concerning 1.32 and he has surrendered at least one run in the first inning in four straight games.

Clevinger has also surrendered at least a run in the first inning in back-to-back starts and, like Bumgarner, has a concerning WHIP (1.26).

The fact that this game is at Petco Park, a pitcher-friendly stadium, is a concern. But the -104 odds here are too enticing with a pair of pitchers that are struggling out of the gate.



MLB First 5 Innings Odds (June 22)

Team 1st 5 Moneyline
New York Mets +106
Houston Astros -130
Team 1st 5 Moneyline
Toronto Blue Jays -110
Chicago White Sox -110
Team 1st 5 Moneyline
Philadelphia Phillies -138
Texas Rangers +112
Team 1st 5 Moneyline
Arizona Diamondbacks TBD
San Diego Padres TBD
Team 1st 5 Moneyline
Colorado Rockies +142
Miami Marlins -176
Team 1st 5 Moneyline
LA Dodgers -158
Cincinnati Reds +128
Team 1st 5 Moneyline
Chicago Cubs TBD
Pittsburgh Pirates TBD
Team 1st 5 Moneyline
Washington Nationals +106
Baltimore Orioles -130
Team 1st 5 Moneyline
Detroit Tigers +124
Boston Red Sox -152
Team 1st 5 Moneyline
New York Yankees -142
Tampa Bay Rays +116
Team 1st 5 Moneyline
San Francisco Giants -105
Atlanta Braves -115
Team 1st 5 Moneyline
Cleveland Guardians TBD
Minnesota Twins TBD
Team 1st 5 Moneyline
St Louis Cardinals -122
Milwaukee Brewers +100
Team 1st 5 Moneyline
Seattle Mariners TBD
Oakland Athletics TBD
Team 1st 5 Moneyline
Kansas City Royals TBD
LA Angels TBD

Odds as of June 21 at FanDuel Sportsbook



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Five games are still off the board at the time of publication., including the two late games (Seattle vs Oakland and Kansas City vs LA Angels).

Phillies vs Rangers First 5 Innings Pick

. The first-half bet I like most on Wednesday is the Phillies as -138 favorites against the Rangers (4:05 pm ET). The Phillies are sending Zack Wheeler to the mound, the 2021 NL Cy Young runner-up, and he’s been almost as good this year as he was last.

Wheeler is 6-3 on the season with a 2.69 ERA and 1.04 WHIP.  His stats would look better but for a rough couple outings near the start of the season when he gave up 11 earned runs in just 8.0 innings of work over two games. Over has last nine starts, he’s surrendered a total of nine runs. That includes four scoreless starts of at least six innings.

One of those scoreless starts just happened to come against these Rangers back in May (a game the Rangers won 2-1 in extra innings).



On the opposite side is an up-and-down Jon Gray (2-3, 4.27 ERA, 1.20 WHIP). While Gray has been excellent in his last two stats, there’s reason to think the Phils’ bats will touch him up on Wednesday. Gray started against Philadelphia on May 3rd of this season and was tagged with five hits, a walk, and three earned runs over just three innings of work.

The Rangers went on to win that game, as well (6-4), but that’s because Philly’s staff struggled on the day.

Pick: Phillies first 5 innings moneyline (-138)


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