Upcoming Match-ups

MLB Opening Day Pitching Matchups and Starting Lineups

Sascha Paruk

by Sascha Paruk in MLB Baseball

Apr 7, 2022 · 8:08 AM PDT

LA Angels celebration
Los Angeles Angels' Shohei Ohtani, center, greets teammate Mike Trout, right, while Seattle Mariners catcher Luis Torrens looks on after Ohtani hit a solo home run during the third inning of a baseball game Friday, April 30, 2021, in Seattle. (AP Photo/Ted S. Warren)
  • The Opening Day pitching matchups and batting orders have been set
  • Only seven games are on the Opening Day schedule, which starts at 2:20 pm ET
  • Below, see the Opening Day starting pitchers and batting orders for all games

The 2022 MLB season starts today with the Milwaukee Brewers vs Chicago Cubs at 2:20 pm ET. Two games were postponed (Yankees vs Red Sox and Mariners vs Twins) leaving just seven games on the schedule for April 7.

The starting lineups and pitching matchups can be found below. This page will be updated throughout the day as more lineups become official.

Jump to: Brewers vs Cubs | Guardians vs Royals | Pirates vs Cardinals | Mets vs Nationals | Reds vs Braves | Astros vs Angels | Padres vs D-Backs

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Brewers vs Cubs Starting Lineups

Position Player Player Position
2B Kolten Wong Rafael Ortega DH
SS Willy Adames Nick Madrigal 2B
LF Christian Yelich Willson Contreras C
DH Andrew McCutchen Ian Happ LF
1B Rowdy Tellez Frank Schwindel 1B
RF Hunter Renfroe Seiya Suzuki RF
C Omar Narvaez Jason Heyward CF
CF Lorenzo Cain Patrick Wisdom 3B
3B Jace Peterson Nico Hoerner SS
Pitcher Corbin Burnes Kyle Hendricks Pitcher

Notes:

Guardians vs Royals Starting Lineups

Position Player Player Position
CF Myles Straw Whit Merrifield RF
LF Ahmed Rosario Bobby Witt Jr 3B
3B Jose Ramirez Andrew Benintendi LF
DH Franmil Reyes Salvador Perez C
1B Bobby Bradley Carlos Santana 1B
2B Yu Chang Hunter Dozier DH
RF Steven Kwan Adalberto Mondesi SS
C Austin Hedges Michael A Taylor CF
SS Andres Gimenez Nicky Lopez 2B
Pitcher Shane Bieber Zack Greinke Pitcher

Notes:

  • Cleveland starter Shane Bieber is back in action after managing just 96.2 innings last season. He is the second-favorite in the AL Cy Young odds, trailing only New York’s Gerrit Cole.
  • Royals 3B Bobby Witt Jr starts the 2022 season as the favorite in the AL Rookie of the Year odds.
  • KC finds itself a +107 home underdog on Opening Day in the Guardians vs Royals odds.

Pirates vs Cardinals Starting Lineups

Position Player Player Position
DH Daniel Vogelbach Dylan Carlson RF
CF Bryan Reynolds Paul Goldschmidt 1B
3B Ke’Bryan Hayes Tyler O’Neill LF
1B Yoshi Tsutsugo Nolan Arenado 3B
SS Kevin Newman Albert Pujols DH
RF Cole Tucker Paul DeJong SS
LF Ben Gamel Yadier Molina C
C Roberto Perez Harrison Bader CF
2B Hoy Park Tommy Edman 2B
Pitcher JT Brubaker Adam Wainwright Pitcher

Notes:

  • The Pirates and Cardinals start the season a full 21 games apart in the MLB win totals. St Louis’ win total has been set at 85.5. Pittsburgh is at a league-low 64.5.
  • St Louis is the biggest favorite of the day, sitting as -210 favorites in the Pirates vs Cardinals odds.

Mets vs Nationals Starting Lineups

Position Player Player Position
RF Starling Marte Cesar Hernandez 2B
DH JD Davis Juan Soto RF
SS Francisco Lindor Nelson Cruz DH
1B Pete Alonso Josh Bell 1B
3B Eduardo Escobar Keibert Ruiz C
2B Robinson Cano Lane Thomas LF
CF Mark Canha Maikel Franco 3B
LF Jeff McNeil Alcides Escobar SS
C James McCann Victor Robles CF
Pitcher Tylor Megill Patrick Corbin Pitcher

Notes:

  • With Max Scherzer and Jacob deGrom both on the shelf due to injuries, youngster Tylor Megill gets the Opening Day nod for the Mets, who sit sixth in the 2022 World Series odds at +1200.
  • Washington’s Juan Soto (+320) is a big favorite in the NL MVP odds, followed by Atlanta’s Ronald Acuna Jr. (+800).

Reds vs Braves Starting Lineups

Position Player Player Position
2B Jonathan India EddieRosario RF
RF Aristides Aquino Matt Olson 1B
LF Tommy Pham Austin Riley 3B
1B Joey Votto Marcell Ozuna LF
C Tyler Stephenson Ozzie Albies 2B
CF Nick Senzel Adam Duvall CF
DH Mike Moustakas Travis d’Arnaud C
SS Kyle Farmer Alex Dickerson DH
3B Brandon Drury Dansby Swanson SS
Pitcher Tyler Mahle Max Fried Pitcher

Notes:

  • The Atlanta Braves start their quest for a second straight World Series title as the fifth-favorite in the World Series odds, despite losing perennial All Star Freddie Freeman to the Dodgers.

Astros vs Angels Starting Lineups

Position Player Player Position
2B Jose Altuve Shohei Ohtani P
DH Michael Brantley Mike Trout CF
3B Alex Bregman Anthony Rendon 3B
LF Yordan Alvarez Matt Duffy 2B
1B Yuli Gurriel Joe Adell LF
RF Kyle Tucker Jared Walsh 1B
SS Jeremy Pena Max Stassi C
CF Chas McCormick Brandon Marsh RF
C Martin Maldonado David Fletcher SS
Pitcher Framber Valdez Shohei Ohtani Pitcher

Notes:

  • Reigning AL MVP Shohei Ohtani starts the 2022 MLB season as the favorite in the AL MVP odds, slightly ahead of teammate Mike Trout and Toronto’s Vlad Guerrero Jr.

Padres vs Diamondbacks Starting Lineups

Position Player Player Position
C Austin Nola Daulton Varsho CF
3B Manny Machado Ketel Marte 2B
2B Jake Cronenworth David Peralta LF
DH Luke Voit Christian Walker 1B
RF Wil Myers Pavin Smith RF
1B Eric Hosmer Carson Kelly C
LF Jurickson Profar Seth Beer DH
SS Ha-Seong Kim Drew Ellis 3B
CF Trent Grisham Geraldo Perdomo SS
Pitcher Yu Darvish Madison Bumgarner Pitcher

 

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