Broncos vs 49ers Player Props to Target in Week 4
By Ryan Potts in NFL News
Published:
- I expect George Kittle to have a productive day attacking the middle of the field
- Brock Purdy’s MVP-like start should continue this week
- Continue reading for my Broncos vs 49ers player props to bet this week
The San Francisco 49ers (3-0) host the Denver Broncos (2-1) at Levi’s Stadium on October 4, 2026, with kickoff set for 4:25 PM ET on CBS. Prop bettors have a big slate of top-tier talent to evaluate as these offenses take the field. For San Francisco, the NFL props market will closely track quarterback Brock Purdy and his distribution to Christian McCaffrey, Deebo Samuel Sr, and Mike Evans.
On the Denver sideline, bettors must weigh the rushing and passing opportunities for Bo Nix and J.K. Dobbins. If you are hunting for value, this breakdown has everything needed to lock in the smartest plays. Keep scrolling to find the absolute best betting angles and predictions to help you navigate the board!
Broncos vs 49ers Player-Prop Odds
Passing Props
Brock Purdy saw his NFL passing yards props total tick up from an opening line of 237.5 to 238.5. Bo Nix experienced a similar increase from 221.5 to 222.5. These upward adjustments suggest bettors anticipate heavy passing volume for both offenses to keep pace with a robust San Francisco attack that averages 32.7 points per game. Both starting quarterbacks sit at a 1.5-passing touchdown line, projecting a balanced scoring distribution through the air.
Rushing & Receiving Props
Christian McCaffrey watched his NFL carries props drop from an opening line of 16.5 to 15.5. JK Dobbins also saw his attempts decline from 14.5 to 13.5, while his rushing yards dipped from 59.5 to 58.5. These movements point to adjusted usage expectations against improving defensive efficiencies. Meanwhile, Jaylen Waddle opened at 56.5 receiving yards before falling to 55.5 heading into kickoff.
Touchdown Props
Kalshi prices below are in cents. The First TD column includes every listed scorer outcome priced above 2¢; “No Touchdown” (1¢) and outcomes priced at exactly 2¢ are excluded.
Christian McCaffrey has the highest listed First TD price at 19¢ and leads the Anytime TD prices at 62¢. JK Dobbins is listed at 11¢ for First TD and 39¢ for Anytime TD. These are Kalshi prices, not traditional sportsbook odds.
Best Broncos vs 49ers Props & Touchdown Picks
George Kittle 60+ Receiving Yards (53¢ / -113 at Kalshi)
San Francisco enters this contest as a small moneyline favorite, which aligns perfectly with Kittle’s most reliable performance split. George Kittle has exceeded 59 receiving yards in seven straight games as a favorite (82.4 receiving yards/game average), commanding a 24.8% target share against zone coverage and averaging an elite 2.42 yards per route run.
With Denver allowing 254.3 passing yards per game this season and surrendering the fifth-most receiving yards to opposing tight ends (69.3 YPG), Kittle is positioned for a nice afternoon. Expect him to move the chains over the middle.
Brock Purdy Over 238.5 Passing Yards (-115 at BetMGM)
San Francisco averages 32.7 points per game and constantly attacks opposing secondaries. At the center of this production is Purdy, who consistently delivers high yardage totals at Levi’s Stadium. Brock Purdy has exceeded 238.5 passing yards in 4 of his last 5 games at home (261.8 passing yards/game average), while ranking 3rd in the NFL with 8.8 yards per pass attempt.
Against a Denver pass defense conceding a 68.4% completion rate on the road and giving up 7.8 net yards per attempt, look for him to air it out and clear this total with ease.
Christian McCaffrey Anytime Touchdown (61¢ / -156 at Polymarket)
With San Francisco converting 90.0% of its red zone opportunities, CMC is in a prime spot to hit paydirt. McCaffrey commands an elite snap share near the goal line – handling 85.7% of the 49ers’ touches inside the 10-yard line and scoring a touchdown in 14 of his last 16 home games – against a Broncos defense that has yielded 1.33 rushing touchdowns per contest.
Grabbing his anytime touchdown prop at 61¢ offers exceptional value compared to traditional sportsbooks.
Ryan Potts is a veteran football and baseball content creator. He was previously a credentialed NFL media member, covering the draft, combine, and Super Bowl. He has been featured on Atlanta sports talk radio and Arizona student radio. Ryan is a journalism graduate from the University of Arizona.
