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Chargers vs 49ers Props – Best Team and Player Prop Bets for Sunday Night Football Week 10

Eric Rosales

by Eric Rosales in NFL Football

Updated Jan 5, 2023 · 7:45 AM PST

Christian McCaffrey spiking football
Oct 30, 2022; Inglewood, California, USA; San Francisco 49ers running back Christian McCaffrey (23) celebrates his touchdown scored against the Los Angeles Rams during the second half at SoFi Stadium. Mandatory Credit: Gary A. Vasquez-USA TODAY Sports
  • The Los Angeles Chargers visit the San Francisco 49ers for Week 10 SNF
  • Get the over/under odds for Justin Herbert, Christian McCaffrey, Austin Ekeler and others
  • A look at some of the Chargers vs 49ers player props can be found below with predictions

We hit it big last Sunday night, landing four out of five prop bets in the Titans-Chiefs game to pull us close to .500, with a chance to get in the black with another good week of picks.

Plenty of great opportunities on the docket, as the Los Angeles Chargers visit the San Francisco 49ers in an all-West Coast showdown from Levi’s Stadium.

The Niners are coming off a bye week — giving mad scientist Kyle Shanahan an extra week of prep to unleash his impressive offensive arsenal that last whipped the Rams 31-14.

As for the Chargers, they’ve won four of their last five, including last week’s 20-17 win in Atlanta.

Let’s look at the the NFL player props available for this matchup and share a few of our favorite picks.

Chargers vs 49ers Player Props

Passer Completions Passing Yards Passing TDs
Jimmy Garoppolo (SF) 21.5 (O +100 | U -135) 243.5 (O -115) | U -115) 1.5 (O -115) | U -115)
Justin Herbert (LAC) 25.5 (O -105 | U -125) 252.5 (O -120 | U -110) 1.5 (O +105) | U -140)
Rusher Longest Rush Rushing Yards Rush + Rec Yards
Austin Ekeler (LAC) 11.5 (O -125 | U -105) 45.5 (O -115 | U -115) 91.5 (O -115) | U -115)
Christian McCaffrey (SF) 16.5 (O -125 | U -105) 80.5 (O -115 | U -115) 120.5 (O -115) | U -115)
Jimmy Garoppolo (SF) OFF 1.5 (O -115 | U -115) OFF
Justin Herbert (LAC) OFF 6.5 (O -110 | U -120) OFF
Receiver Receptions Receiving Yards Longest Reception
Austin Ekeler (LAC) OFF 41.5 (O -115 | U -115) 15.5 (O -115 | U -115)
Brandon Aiyuk (SF) 4.5 (O +120 | U -155) 55.5 (O -115 | U -115) 22.5 (O -115 | U -115)
Christian McCaffrey (SF) 4.5 (O -125 | U -105) 36.5 (O -115 | U -115) 14.5 (O -125 | U -105)
DeAndre Carter (LAC) 3.5 (O +110 | U -150) 37.5 (O -115 | U -115) 17.5 (O -115 | U -115)
Deebo Samuel (SF) 4.5 (O -110 | U -120) 50.5 (O -120 | U -110) 20.5 (O -120 | U -110)
George Kittle (SF) 3.5 (O -140 | U +105) 42.5 (O -115 | U -115) 18.5 (O -115 | U -115)
Gerald Everett (LAC) 4.5 (O +120 | U -155) 42.5 (O -115 | U -115) 17.5 (O -115 | U -115)
Jajuan Jennings (SF) 1.5 (O -115 | U -115) 16.5 (O -110 | U -120)) 12.5 (O -110 | U -120)
Josh Palmer (LAC) 4.5 (O -180 | U +135) 54.5 (O -110 | U -120)) 20.5 (O -110 | U -120)
Kyle Juszczyk (SF) 1.5 (O +115 | U -155) 9.5 (O -115 | U -115) OFF

Odds as of November 13 at DraftKings Sportsbook

In the odds above, Justin Herbert is favored to throw for less than two TD passes, and has a passing total of 252.5. Christian McCaffrey has the highest listed rush total at 80.5, while the highest receiving total is given to Brandon Aiyuk at 55.5 yards.

Prop #1: Christian McCaffrey Rushing Yards

The 49ers showed the multitude of ways they plan to use the talents of newly acquired Christian McCaffrey in their win over the Rams. The ex-Panther ran for 94 yards on 18 carries and a TD, caught nine balls for 55 yards and TD, and he threw a 34-yard TD pass to Brandon Aiyuk.

That was after just one full week of practice. Now, coming off a bye week, it should be all systems go for the centrepiece of the San Fran attack.

Two wagers really stand out here. The first is his rushing yards total. Los Angeles features the 5th-worst run defense in the NFL, surrendering 145.5 yards per game, while giving up a league-best 5.7 yards per tote.

I also really like CMC’s longest run prop of 16.5 yards. The Chargers have allowed at least one running back to top this total in all but one game this season, when Denver’s longest run went for 14 yards.

Look for McCcaffrey to be a workhorse in Week 10, and cash in on it.

Picks: 

  • McCaffrey OVER 80.5 yards rushing (-115); 1 unit to win 0.87 units
  • McCaffrey OVER 16.5 yards longest rush (-125); 1.5 units to win 1.2 units

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Prop #2: Herbert Passing Yards & Carter Receptions

Since a blistering start to the year, where he averaged 312.5 passing yards per game, Justin Herbert has been somewhat contained in his previous four starts, where he’s averaging 251 yards.

His top two receivers, Keenan Allen and Mike Williams, are injured and aren’t available Sunday night.

Couple that with the fact the 49ers have the 9th-ranked pass defense — one of nine teams to hold the opposition to under 200 yards passing per game (199.7), while allowing just 6.3 yards per attempt (T-8th) — and it equals a tough passing day.

Without his top targets, and the 49ers’ ability to bring pressure (6th-most sacks on the year with 26), they’ll be hard pressed to find those big chunk plays.

That being said, someone is going to need to catch the ball, and DeAndre Carter should be looked at favorably, with Josh Palmer sliding into that top pass-catcher role, and more of the Niners’ attention. Last week, he caught five balls on six targets against the Falcons.

His usage is the key here: minus Allen and Williams the previous two games, he saw 94% of the snaps against Atlanta and 83% against Seattle. Prior to that, he hadn’t seen more than 74% snaps in a game all season.

Pick:

  • Herbert UNDER 252.5 rushing yards (-110); 1 unit to win 0.91 units
  • Carter OVER 3.5 receptions (+110); 1 unit to win 1.10 units

Chargers vs 49ers Scoring Props

Player Odds to Score 1st TD Odds to Score Any TD
Christian McCaffrey (SF) +350 -195
Austin Ekeler (LAC) +700 -115
Brandon Aiyuk (SF) +650 +115
George Kittle (SF) +750 +135
Deebo Samuel (SF) +750 +135
Elijah Mitchell (SF) +800 +145
Josh Palmer (LAC) +1400 +210
Gerald Everett (LAC) +1600 +245
DeAndre Carter (LAC) +1900 +290
Michael Bandy (LAC) +2000 +390
Ray-Ray McCloud (SF) +1800 +390

Chargers vs 49ers Touchdown Scorer Odds

McCaffrey has scored at least one TD in 12 of his last 14 appearances coming off a win. Deebo Samuel (+135) has hit paydirt frequently on California soil: he’s scored at least one TD in seven of his last nine appearances playing in the state.

For the visitors, Austin Ekeler has been living in the endzone as of late, scoring two or more touchdowns in four of the Chargers’ last five games. You can get +475 odds on that from DraftKings right now.

Picks:

  • Ekeler ANYTIME TD scorer (-115); 1 unit to win 0.87 units
  • Week 9 Record: 4-1; Overall SNF props record: 16-17, -1.88 units

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