Detroit Lions vs San Francisco 49ers Player Props – Best Prop Bets for MNF Week 17

By John Hyslop in NFL Football
Published:

- The final NFL Week 17 game is a matchup between the Detroit Lions and San Francisco 49ers
- This game is meaningless to both teams but we can always find a way to bet player props
- Find two of my favorite Lions vs 49ers player props to bet for this MNF matchup on Dec. 30
We’re got one last shot at greatness in Week 17 and I’m thinking we should take it. We don’t have a lot of season left and it won’t be long until we’re wishing we had a football game to bet on. We go through this every single year. The only issue I see tonight is the fact that this is a meaningless game. It’s shocking but true. When the NFL pitted the Detroit Lions and San Francisco 49ers against each other in Week 17, I’m sure they had no idea that the game would mean nothing. It’s nobody’s fault. Still, I’m pretty sure we can get a few player prop bets in on this thing and make it at least mean something to us. It’s definitely the move.
Lions vs 49ers Player Prop Picks
Player | Rushing Attempts | Rushing Yards | Pick |
---|---|---|---|
Jahmyr Gibbs (Lions) | 18.5 (Ov -120 / Un -110) | 89.5 (Ov -125 / Un -105) | 100+ Rushing Yards (+120) |
Player | Receptions | Receiving Yards | Pick |
Deebo Samuel (49ers) | 4.5 (Ov +108 / Un -140) | 48.5 (Ov -110 / Un -100) | Over 4.5 Receptions (+108) |

Jahmyr Gibbs Is an Animal
When the Detroit Lions drafted Jahmyr Gibbs in the first round, the experts were pissed. Everyone said it was way too high to draft a running back and that the Lions were idiots. Fast-forward to today and all of those “experts” were 100% wrong. Gibbs is an absolute stud and might be the best running back the Detroit Lions have ever rostered.
People think the man can literally do the impossible.
When you’re down 50 in your fantasy football championship and have Jahmyr Gibbs left. 🥵 pic.twitter.com/3FFjbsMW2L
— theScore (@theScore) December 30, 2024
Here’s the thing with this one, we’re going to need volume to get home. I’m not saying 25+ carries type of volume but he’ll definitely need to go 17+ in the rushing attempt category. Given the fact that this game means nothing, it’s a gamble but one I’m willing to take.
Dan Campbell is not an ordinary coach and he’ll likely play his starters the entire game unless it turns into a beatdown. The idea of him resting guys before they play the Minnesota Vikings next week is kind of crazy. My guess is they treat this game like any other.
If and when that happens, we should see Gibbs run wild on the 49ers. The best way to attack San Francisco is on the ground. Everyone knows that. Four fo the last five starting running backs have all gone for 100+ rushing yards against these guys. They just don’t have the will to stop anyone. It’s sad when you think about it.
- The Pick: Jahmyr Gibbs 100+ Rushing Yards (+120) at ESPNBet
Deebo Samuel Will Get Loose Tonight
Anyone who took Deebo Samuel in the second round of their fantasy draft knows exactly what’s about to happen tonight. It’s just how this whole game we play works. We miss badly on a second-round pick that causes us to never be in contention, then that bust goes off when we don’t need him.
One thing we know about Deebo is, it looks like he’ll fight to the bitter end.
Dk Metcalf and Deebo Samuel fighting for the last floatie in Cancun pic.twitter.com/fEWMgLO5YE
— 🦑 (@CBAS5S) December 30, 2024
Don’t believe me? Go back and look at what has happened over the last couple weeks. Deebo literally tweeted out that he wanted more touches. I’m not sure if that’s exactly what he said but that was basically the gist of it.
Keep in mind, right after his tweet (and after he tanked every fantasy season), he immediately started getting targets. The first game was against the Los Angeles Rams but that game was played in pretty bad weather. He was only able to turn his seven targets into three catches for 16 yards. Everyone still though he stunk.
Then last week in Miami, he was targeted nine times which he turned into a 7-96-1 line. My guess is we see more of the same tonight except this game is against the team that has given up the third most receptions to the wide receiver position this season. The weather looks nice and the Niners have nothing to lose. Deebo is catching at least five passes tonight. Feels right.
- The Pick: Deebo Samuel Over 4.5 Receptions (+108) at FanDuel
- 2024 SBD MNF Results – 14-17 (+1.44 Units)
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John has spent the past 20+ years betting sports on a daily basis and is considered by many to be a walking sports betting encyclopedia. From obscure player props to sides and totals, if there is an angle, John will find it.