Opening NFL Week 2 Odds – Point Spread, Moneyline & Total for All 16 Games
By Sascha Paruk in NFL Football
Published:
- Odds are starting to be released for NFL Week 2, which runs from Thursday, Sep. 12, to Monday, Sep. 16
- The Week 2 slate is highlights by the Buffalo Bills vs Miami Dolphins on Thursday Night Football
- Below, see the opening NFL Week 2 odds for every game on the schedule
A handful of late-afternoon Week 1 games are still in progress, but oddsmakers have already turned their attention to Week 2 in the NFL, with the odds for more than half of the matchups already posted.
Week 2 starts with a heavyweight AFC East tilt between the Buffalo Bills and Miami Dolphins on Thursday Night Football on Sep. 12 and wraps up with the Atlanta Falcons vs Philadelphia Eagles on Monday, Sep. 16. The other 14 games are all on Sunday, Sep. 15.
The table below lists the opening moneyline, point spread, and game total for every Week 2 NFL game in chronological order. The table will be updated as more Week 2 NFL lines are posted.
NFL Week 2 Odds
Team | Moneyline | Spread | Over/Under | Date/Time |
---|---|---|---|---|
Buffalo Bills | +102 | +1.5 (-110) | Over 50.5 (-110) | Thursday, Sep. 12 |
Miami Dolphins | -120 | -1.5 (-110) | Under 50.5 (-110) | 8:15 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
New Orleans Saints | +235 | +6.5 (-110) | Over 45.5 (-110) | Sunday, Sep. 15 |
Dallas Cowboys | -290 | -6.5 (-110) | Under 45.5 (-110) | 1:00 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
Tampa Bay Buccaneers | +265 | +6.5 (-110) | Over 48.5 (-110) | Sunday, Sep. 15 |
Detroit Lions | -330 | -6.5 (-110) | Under 48.5 (-110) | 1:00 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
Indianapolis Colts | -154 | -2.5 (-110) | Over 41.5 (-110) | Sunday, Sep. 15 |
Green Bay Packers | +130 | +2.5 (-110) | Under 41.5 (-110) | 1:00 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
New York Jets | -230 | -4.5 (-110) | Over 42.5 (-110) | Sunday, Sep. 15 |
Tennessee Titans | +190 | +4.5 (-110) | Under 42.5 (-110) | 1:00 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
San Francisco 49ers | -290 | -6.5 (-110) | Over 45.5 (-110) | Sunday, Sep. 15 |
Minnesota Vikings | +235 | +6.5 (-110) | Under 45.5 (-110) | 1:00 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
Seattle Seahawks | -198 | -3.5 (-110) | Over 40.5 (-110) | Sunday, Sep. 15 |
New England Patriots | +166 | +3.5 (-110) | Under 40.5 (-110) | 1:00 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
New York Giants | +128 | +2.5 (-110) | Over 42.5 (-110) | Sunday, Sep. 15 |
Washington Commanders | -152 | -2.5 (-110) | Under 42.5 (-110) | 1:00 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
Los Angeles Chargers | -240 | -4.5 (-110) | Over 39.5 (-110) | Sunday, Sep. 15 |
Carolina Panthers | +198 | +4.5 (-110) | Under 39.5 (-110) | 1:00 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
Cleveland Browns | +132 | +3 (-110) | Over 43.5 (-110) | Sunday, Sep. 15 |
Jacksonville Jaguars | -156 | -3 (-110) | Under 43.5 (-110) | 1:00 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
Las Vegas Raiders | +360 | +8.5 (-110) | Over 43.5 (-110) | Sunday, Sep. 15 |
Baltimore Ravens | -460 | -8.5 (-110) | Under 43.5 (-110) | 1:00 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
Los Angeles Rams | -134 | -1.5 (-110) | Over 49.5 (-110) | Sunday, Sep. 15 |
Arizona Cardinals | +114 | +1.5 (-110) | Under 49.5 (-110) | 4:05 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
Pittsburgh Steelers | -154 | -2.5 (-110) | Over 39.5 (-110) | Sunday, Sep. 15 |
Denver Broncos | +130 | +2.5 (-110) | Under 39.5 (-110) | 4:25 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
Cincinnati Bengals | +235 | +6.5 (-110) | Over 47.5 (-110) | Sunday, Sep. 15 |
Kansas City Chiefs | -290 | -6.5 (-110) | Under 47.5 (-110) | 4:25 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
Chicago Bears | +225 | +5.5 (-110) | Over 46.5 (-110) | Sunday, Sep. 15 |
Houston Texans | -255 | -5.5 (-110) | Under 46.5 (-110) | 8:20 pm ET |
Team | Moneyline | Spread | Over/Under | Date/Time |
Atlanta Falcons | +198 | +5.5 (-110) | Over 48.5 (-110) | Monday, Sep. 15 |
Philadelphia Eagles | -240 | -5.5 (-110) | Under 48.5 (-110) | 8:15 pm ET |
The early Week 2 NFL odds list the Bills vs Dolphins matchup on TNF with the narrowest spread of the week with Miami opening as just 1.5-point home favorites.
Odds as of Sep. 8 at FanDuel and DraftKings. Get the latest promo code for DraftKings to bet on NFL Week 2.
Biggest NFL Week 2 Point Spread: Ravens -8.5 vs Raiders
Only one point spread on the board in the Week 2 NFL odds is more than a touchdown, and that comes in the Las Vegas vs Baltimore matchup where the 0-1 Ravens are 8.5-point home favorites over the 0-1 Raiders. Baltimore went toe-to-toe with defending-champion Kansas City on TNF in Week 1 (meaning they’ll have extra time to prepare), coming out on the wrong end of a 27-20 scoreline.
The Raiders, meanwhile, were outclassed 22-10 on the road by the Chargers. New QB Gardner Minshew wasn’t terrible, going 25/33 for 257 yards, one TD, and one interception, but a -3 turnover margin spelled doom for the Silver and Black.
Vikings Big Underdogs to 49ers Despite Impressive Season-Opening Win
If you want proof that oddsmakers are taking the Week 1 results with a grain of salt, look no further than the San Francisco vs Minnesota matchup in the Twin Cities. The Vikings are coming off a resounding 28-6 win on the road against the New York Giants, a game they controlled from start to finish. Yet Minnesota has opened as nearly a touchdown underdog at home to the reigning NFC-champion 49ers.
New starter Sam Darnold was on point, going 19/24 for 208 yards and two touchdowns while spreading the ball around to one of the NFL’s best receiving corps. The Minnesota defense, meanwhile, held the Giants to just 240 total yards of 68 plays (3.5 yards per play) while also generating two interceptions.
Absolutely inexcusable from Daniel Jones on his 2nd Interception today, behind the receiver into double coverage. pic.twitter.com/6EiCRnxZr0
— Joe Vostal (@jvostal42) September 8, 2024
San Francisco, which faces Aaron Rodgers and the New York Jets on Monday Night Football tomorrow, will be on a short week.
Harbaugh’s Chargers 4.5-Point Road Favorites at Abysmal Panthers
After a horrendous 2-15 campaign last year, the Carolina Panthers picked up where they left off in Week 1 of 2024, getting embarrassed 47-10 by division-rival New Orleans. Carolina was down 17-0 by the end of the first quarter and trailed 30-0 late in the first half before finally getting on the board.
Sophomore QB Bryce Young showed no growth from his disastrous rookie season, going just 13/30 for 161 yards and two interceptions.
The Chargers, meanwhile, took care of business as 3.5-point home favorites against the Raiders, overcoming an early 7-3 deficit en route to a decisive 22-10 victory in the first game of the Jim Harbaugh era. Former Raven JK Dobbins was absolutely electric spelling Gus Edwards, rushing for 135 yards and a touchdown on just 10 carries, including this 61-yard scamper.
jk dobbins the man that u are
📺 | @nfloncbs pic.twitter.com/YZGjq4cXYm
— Los Angeles Chargers (@chargers) September 8, 2024
Dobbins went nearly 100 yards over his rushing-yard total of 36.5 in the Week 1 NFL props.
Despite Carolina’s brutal Week 1 showing and LAC’s relatively strong start under Harbaugh, the Chargers have opened Week 2 as relatively slim 4.5-point road favorites against the worst team in the league at the moment.
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Managing Editor
Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.