NFL Week 11 Odds – Opening Betting Lines & Spreads for All Games

• NFL Week 11 begins with the Packers hosting the Titans on Thursday Night Football
• The Ravens are the biggest opening favorites by 12.5 points over the Panthers
• A look at all the NFL Week 11 opening odds can be found below with some early picks

Week 11 of the NFL season begins with Thursday Night Football as the Green Bay Packers host the Tennessee Titans.

The Packers have opened as two-point favorites.

Sunday Night Football will feature Chiefs vs Chargers. It will 49ers vs Cardinals in Mexico City on Monday Night Football. The Chiefs are favored by 6.5 points and the 49ers are seven-point picks.

The NFL odds will be updated throughout the week.

NFL Week 11 Opening Odds

Odds as of November 13th at FanDuel.

The biggest opening favorites are the Baltimore Ravens by 12.5 points over the Carolina Panthers. The New Orleans Saints are the smallest favorites at 1.5 points over the Los Angeles Rams.

Primetime games have the largest and smallest over/unders. The total is 50 points for Chiefs vs Chargers and 38.5 for Titans vs Packers.

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Browns vs Bills Early Odds & Prediction

The Buffalo Bills (6-3) are seven-point favorites at home over the Cleveland Browns (3-6) on Sunday despite losing back-to-back games.

The Bills fell to the Minnesota Vikings 33-30 in overtime on Sunday at home. Josh Allen had three turnovers in the fourth quarter and OT, including throwing an interception with 1:12 left in the extra session that ended the game.

The Browns lost for the fifth time in six games, getting beat 37-17 by the Dolphins in Miami. Cleveland allowed Tua Tagovailoa to throw three touchdown passes.

Even though the Bills are struggling, this line seems light as they are clearly more than a touchdown better than the Browns.

Pick: Bills -7 (-110)

Cowboys vs Vikings Early Odds & Prediction

The Dallas Cowboys (6-3) are 2.5-point road favorites over the Vikings (8-1) in the late-afternoon window on Sunday.

Patrick Peterson’s interception of Allen in the end zone sealed the Vikings’ victory. Minnesota ran its winning streak to seven games.

Kirk Cousins threw for 357 yards on 30-of-50 passing with one touchdown and two interceptions. The TD went to Justin Jefferson, who had a monster game with 10 receptions for 193 yards.

Just throw it to @JJettas2

📺: @NFLonFOX pic.twitter.com/iOzht9ddoU

— Minnesota Vikings (@Vikings) November 13, 2022

The Cowboys lost to the Packers 31-28 in overtime in Green Bay and are 2-2 since a 4-1 start to the season. The Cowboys were burned by three Aaron Rodgers’ TD passes to rookie Christian Watson.

Many analysts have been skeptical of the Vikings because of their weak schedule but proved Sunday they can beat a quality team. Minnesota looks good with the points here.

Pick: Vikings +2.5 (-110)

Chiefs vs Chargers Early Odds & Prediction

The Chiefs (7-2) beat the visiting Jaguars for their third straight win on Sunday behind Patrick Mahomes, who passed for 331 yards and two touchdowns.

Acquired from the New York Giants earlier in the month, Kadarius Toney had 33 yards rushing, caught four passes for 57 yards and scored his first NFL touchdown. Travis Kelce, Marquez Valdes-Scantling and Noah Gray also had touchdown catches for the Chiefs.

IT'S TONEY TIME. pic.twitter.com/VaWS3WzyIr

— Kansas City Chiefs (@Chiefs) November 13, 2022

The Chargers (5-3) played at the San Francisco 49ers on Sunday night having won four of their last five games. Look for them to give the Chiefs a tussle next Sunday night.

Pick: Chargers +6.5 (-110)