NFL Week 8 Odds – Opening Betting Lines & Spreads for All Games

• The Buccaneers are 1.5-point home favorites over the Ravens on Thursday night to open NFL Week 8
• The unbeaten Eagles are the biggest NFL Week 8 favorites at 10.5 points over the visiting Steelers
• A look at all the NFL Week 8 opening odds and spreads can be found below with early predictions

The Baltimore Ravens open Week 8 of the NFL season by visiting the Tampa Bay Buccaneers for Thursday Night Football.

The Buccaneers have opened as 1.5-point favorites despite losing to the Carolina Panthers 21-3 on Sunday on the road. The Ravens held off the Cleveland Browns 23-20 in Baltimore.

Sunday Night Football will feature Packers vs Bills in Buffalo. It will be Bengals vs Browns on Monday Night Football in Cleveland. Buffalo has opened as a 10-point pick and Cincinnati is favored by three points.

The NFL odds will be updated throughout the week

NFL Week 8 Opening Odds

Odds as of October 23rd at DraftKings Sportsbook. Claim a DraftKings Sportsbook promo code. 

The unbeaten Philadelphia Eagles are the biggest favorites on the board by 10.5 points over the visiting Pittsburgh Steelers. The smallest favorites are the San Francisco 49ers, who are one-point road picks over the Los Angeles Rams.

The highest over/under is 50.5 for Dolphins vs Lions. The total of 40 for Broncos vs Jaguars in London is the lowest on the board.

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NFL Week 8 Predictions

Broncos vs Jaguars Early Odds & Prediction

As evidenced by over/under of 40, the matchup between the Broncos and Jaguars at 9:30 a.m. ET Sunday at Wembley Stadium doesn’t shape up to be a barnburner. However, the opening number on this game seems high with Jacksonville favored by 4.5 points.

While the Jaguars have shown improvement in Doug Pederson’s first year as coach, they are just 2-5. That matches the record of the disappointing Broncos and seemingly overmatched rookie coach Nathaniel Hackett.

Hevertheless, the line should be a little closer.

The Jaguars’ losing streak reached four games Sunday as they fell to the New York Giants 23-17 at home. Jacksonville’s Christian Kirk was tackled inside the Giants’ 1-yard line as time expired as New York held on.

WHAT A GAME 🤯

The @Giants defense stops Christian Kirk INCHES away from the game-winning TD!

(via @NFL)pic.twitter.com/TGMZXzFzBe

— Sports Illustrated (@SInow) October 23, 2022

Jaguars quarterback Trevor Lawrence was 22-of-43 passing for 310 yards.

Playing without injured QB Russell Wilson, the Broncos also lost their fourth straight game, 16-9 to the visiting New York Jets. Brett Rypien made his second career start and completed 24 of 46 passes for 225 yards with no touchdowns and one interception.

there legitimately wasn't a Broncos receiver within 25 yards of this Brett Rypien throw pic.twitter.com/7Ib7lG86bt

— Christian D'Andrea (@TrainIsland) October 23, 2022

Regardless of whether Wilson plays or not, the Broncos’ defense is good and should be able to keep the game close.

Pick: Broncos +4.5 (-114)

Ravens vs Buccaneers Early Odds & Prediction

Both teams who fancied themselves as Super Bowl contenders at the beginning of the season but have struggled at times meet at 8:15 p.m. ET Thursday at Raymond James Stadium in Tampa. The Buccaneers (3-4) have opened as a 1.5-point favorite over the Ravens (4-3).

The Ravens got by the Cleveland Browns 23-20 on Sunday at home. Gus Edwards sparked Baltimore by scoring two touchdowns and rushing for 66 yards in his return from major knee surgery that forced him to miss last season and the first six games of 2022.

GUS BUS KEEPS ROLLING 🚌🚌

Tune in on CBS! @GodsGiftGus13 pic.twitter.com/7WyrMVBom0

— Baltimore Ravens (@Ravens) October 23, 2022

The Ravens won even though Lamar Jackson was limited to 120 yards passing while being sacked three times.

The Buccaneers and Tom Brady took a bad loss, getting stunned 21-3 by the Carolina Panthers in Charlotte as 13.5-point favorites.

Brady passed for 290 yards while completing 32 of 49 attempts. However, a sign of what kind of day it was going to be for the Buccaneers when Mike Evans dropped what would have been a 64-yard touchdown pass on the third play of the game.

Tom Brady might strangle Mike Evans pic.twitter.com/KvKzEinMPv

— Carrington Harrison (@cdotharrison) October 23, 2022

The Buccaneers look like a team in serious trouble and the wrong team is favored here.

Pick: Ravens +1.5 (-106)

Packers vs Bills Early Odds & Prediction

The Green Bay Packers and descending quarterback Aaron Rodgers visit the Buffalo Bills and ascending QB Josh Allen at 8:20 p.m. ET Sunday at Highmark Stadium in Orchard Park, N.Y. The Bills (5-1) are 10-point picks over the skidding Packers (3-4).

The Bills had their bye this weekend after winning three games in a row. Buffalo beat the Kansas City Chiefs 24-20 on Oct. 16 on the road in its last outing.

The Packers’ losing streak reached three games Sunday with a 23-21 road loss to the Washington Commanders. Hampered by a sore thumb, Rodgers was 23 of 35 for 194 yards.

Aaron Rodgers after the last play of the Packers-Commanders game. pic.twitter.com/e9atAQ4LXE

— FOX Sports: NFL (@NFLonFOX) October 23, 2022

The Packers failed to convert any of their six third downs. They were also held to 232 total yards.

The double-digit spread seems high at first glance, but these are two teams trending in a different direction. Look for the Bills to cover.

Pick: Bills -10 (-110)