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Lions vs Eagles Picks, Closing Odds & Betting Splits for SNF

Sascha Paruk

By Sascha Paruk in NFL News

Published:


Detroit Lions quarterback Jared Goff and wide receiver Amon-Ra St. Brown celebrate a TD
Detroit Lions quarterback Jared Goff (16) celebrates a touchdown against Washington Commanders scored by wide receiver Amon-Ra St. Brown (14) during the first half at Northwest Stadium in Landover, Md. on Sunday, November 9, 2025.
  • NFC division leaders clash when the Detroit Lions visit the Philadelphia Eagles on SNF
  • The Lions/Eagles odds have moved towards Philly, but the public loves Detroit to cover the spread
  • See my Lions vs Eagles picks and predictions, plus the closing odds and betting splits

A pivotal NFC clash with significant playoff implications unfolds in Week 11 as the prolific Detroit Lions (6-3, 3-2 away, 6-3 ATS, 5-4 O/U) travel to face the reigning Super Bowl-champion Philadelphia Eagles (7-2, 3-1 home, 6-3 ATS, 5-4 O/U) in a primetime showdown. This Sunday Night Football matchup kicks off at 8:20 p.m. pm ET at Lincoln Financial Field.

With the Lions’ secondary significantly compromised by injuries, the line has moved a point towards the Eagles over the course of the week (from PHI -1.5 to -2.5). Is that too much disrespect to the ever-dangerous Lions or sensible movement towards the healthier champs? Below, I have set out my favorite Lions vs Eagles picks, plus the closing SNF odds and the public-betting splits.

Lions vs Eagles Expert Picks & Predictions

DET vs PHI ATS Pick: Eagles -2.5 (-115) at bet365

This Week 11 clash presents a fascinating tactical battle, but the game’s outcome hinges on a critical mismatch: Philadelphia’s precision passing attack against a severely depleted Detroit secondary. While the Lions boast superior offensive numbers, averaging 31.0 points and 372.4 yards per game compared to Philadelphia’s 24.2 points, the Eagles’ ruthless efficiency in key moments could prove decisive.

The Eagles hold a commanding advantage in red-zone execution, converting an astounding 81.0% of their attempts into touchdowns compared to Detroit’s 68.4% rate. This 12.6% difference becomes magnified when considering the Lions’ secondary concerns, with cornerback Terrion Arnold in concussion protocol and DJ Reed battling a hamstring injury.

    The market movement from Eagles -1.5 to -2.5 early in the week reflected sharp money recognizing Philadelphia’s health advantage and tactical edge in the passing game. With Jalen Hurts facing potential favorable matchups against backup DBs, the Eagles’ aerial attack should find consistent success.

    With Saquon Barkley an omnipresent threat in the Philadelphia backfield, it’s not like the Lions can empty the box and devote extra resources in coverage.

    The combination of home-field advantage, superior health, and a decisive edge in the secondary creates compelling value on Philadelphia laying the short number. The Lions’ explosive offense will generate points, but their inability to generate consistent stops against the pass ultimately tilts this contest toward the home team.

    DET vs PHI Game Total Pick: Over 46.0 (-122) at BetRivers

    Both offenses possess the firepower to push this total over the posted number. Detroit’s 31.0 points per game and Philadelphia’s 81.0% re-zone efficiency suggest scoring opportunities throughout. The Lions’ defensive injuries should provide additional possessions and favorable field position for an Eagles offense that’s averaging 28.0 PPG at home this season.

    Best DET vs PHI Player Prop: AJ Brown Over 59.5 Receiving Yards (-115) at BetMGM

    This line appears drastically undervalued given Brown’s target share and the favorable matchup. With Detroit’s top cornerback potentially sidelined, Brown should see single coverage throughout the contest. His consistent performance, combined with the tactical mismatch, makes this prop a strong play.

    Detroit Lions vs Philadelphia Eagles Closing Odds

    In the hours before kickoff, the Lions/Eagles spread sits at PHI -2.5 across the board, with most books juicing the Eagles pretty heavily. The best ATS price on Philly at the moment is -2.5 (-115) at bet365. The best ATS option for the Lions is +2.5 (+102) at Underdog. On the moneyline, DraftKings has the best price for Detroit at +130 (43.48% implied win probability), while BetMGM has the best price for Philadelphia at -140 (58.33% implied win probability).

    The game total ranges from 46.0 to 47.0. Under bettors should take U 47.0 (-115) at BetMGM, while over bettors should take O 46.0 (-122) at BetRivers.

    DET vs PHI Odds Movement & Betting Splits

    The Lions/Eagles odds opened with Philly as just a 1.5-point ATS favorite and very slight -116 moneyline chalk. The game total has ticked down a touch from the opening number of 47.5.

    Now that the spread has grown to DET +2.5, there is heavy betting on the Lions to cover: Detroit is getting 79% of ATS handle on 76% of ATS wagers in the Week 11 NFL public betting splits.

    The moneyline splits show a potential public-vs-sharps divide. Philly is getting 61% of the moneyline tickets, but the Lions are getting a massive 84% of ML handle, meaning that much larger bets are on Detroit to win straight-up, potentially from professional bettors.

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    Sascha Paruk
    Sascha Paruk

    Managing Editor

    Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.

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