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Landaluce vs Medvedev Odds, Picks & Predictions in Rome QF

Sascha Paruk

By Sascha Paruk in Tennis

Published:


Daniil Medvedev on the court
Daniil Medvedev hits to Jannik Sinner in the menÕs singles championship final at the BNP Paribas Open in Indian Wells, Calif., Sunday, March 15, 2026.
  • Landaluce +3.5 games provides massive value
  • The over (21.5 games) is another strong bet
  • See my top Landaluce vs Medvedev picks and predictions

Get ready for an intriguing quarterfinal clash at ATP Rome as 20-year-old world #94 Martin Landaluce takes on 30-year-old world #9 Daniil Medvedev at 9:00 am ET.

Medvedev enters the court as the heavy favorite, looking to capitalize on a deep tournament run to bolster his top-five status in the ATP singles race. Across the net stands the heavy underdog, Spain’s Martin Landaluce. Will the rising underdog string together enough holds of serve to pull off a monumental upset, or will the seasoned top-tier favorite handle his business and cruise to the semifinals?

I will break down everything you need to know before locking in your wagers.

Landaluce vs Medvedev: Best Odds

PlayerMoneylineSpreadTotal Games
Martin Landaluce+245 at Kalshi+3.5 (-120) at bet365O 21.5 (-133) at Kalshi
Daniil Medvedev-257 at Kalshi-3.5 (+100) at KalshiU 22.5 (-120) at bet365
The odds displayed in the table above are from bet365 at 1:32 pm ET, May 13, and are subject to change before the first serve.

Medvedev is priced at 72 cents to win at prediction site Kalshi, which is equal to -257 odds in traditional sports-betting terms. Landaluce is trading at 29 cents, which is the equivalent of a +245 price in American odds.

All sites have the game spread at Medvedev -3.5. Landaluce backers can get the Spaniard at even-money to cover at Kalshi.

Martin Landaluce vs Daniil Medvedev Picks

The Over 22.5 total games is my lead play for this quarterfinal matchup and pairs perfectly with the Landaluce spread bet on this card. The total is set at 22.5 with both sides priced at -120 on Bet365. Here is why I am hammering the Over.

Over 21.5 Total Games (-133)

Prediction Markets
Landaluce vs Medvedev OU Pick
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Kalshi
Over 21.5 Games
57%

Medvedev is one of the most elite baseline defenders on Tour. His defensive style naturally extends rallies and produces longer service games. I expect early-match feeling-out periods and extended deuce games as both players adjust to each other’s patterns.

Medvedev’s unorthodox flat groundstrokes are notoriously difficult to time on a first meeting, which should lead to longer rallies and more games needed to find a break.

On hard courts, Medvedev relies on an elite first serve that yields a high number of free points, maintaining a service hold rate often hovering above 85%. On slow European clay, however, the surface absorbs the pace of his flat serve.

Without those free points, Medvedev is forced into grinding baseline rallies. In the Round of 32 here in Rome, he already dropped a set to Pablo Llamas Ruiz (another young Spanish clay-courter), indicating his serve is indeed breakable in these conditions.

I am confident this one pushes past the 21.5 threshold comfortably.

Martin Landaluce +3.5 Games (+100)

Prediction Markets
Landaluce vs Medvedev Spread Pick
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Kalshi
Landaluce +3.5
50%

While Medvedev is the clear favorite to advance, taking Landaluce to cover the +3.5 game spread offers an incredibly intriguing situational angle.

While Medvedev’s overall ATP Elo rating dwarfs most of the tour, his surface-specific Elo on clay historically drops significantly compared to his hard-court peak. Medvedev famously struggles with movement and the high bounce on red dirt.

Conversely, Landaluce’s short-term clay Elo is currently spiking. Coming through qualifying, Landaluce has already won five consecutive matches in Rome, defeating veterans like Marin Cilic and rising stars like Hamad Medjedovic in the Round of 16. Because Elo ratings weight recent performance and unexpected upsets heavily, Landaluce’s “form rating” (short-term Elo) is at an absolute peak.

Medvedev statistically stands deeper to return serve than almost anyone on the ATP tour. While this works brilliantly against flat hard-court serves, it is a mathematical disadvantage against Spanish kick serves on clay. Landaluce can utilize heavy topspin serves out wide. By the time the ball reaches Medvedev near the back fence, it will be above his shoulders – a strike zone he actively dislikes.

Landaluce grew up on this surface. His service hold rate on clay is protected by a high first-serve percentage, heavy topspin, and excellent “Serve +1” forehand execution. If Landaluce can consistently hold serve at an 80%+ rate in this match, covering +3.5 games becomes highly probable.

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Sascha Paruk
Sascha Paruk

Managing Editor

Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.

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