Best Home Run Picks & Odds Across Today’s MLB Slate

• A massive 15-game MLB slate provides high-leverage home run prop opportunities across several hitter-friendly venues.
• Hunter Goodman and CJ Abrams stand out as premium power targets in a highly favorable environment at Nationals Park.
• Yordan Alvarez offers elite volume upside at Yankee Stadium, despite facing an unannounced starting pitcher.

Welcome to a massive 15-game MLB slate with plenty of home run prop value across hitter-friendly venues and star-heavy matchups. For the full market board, see our MLB home run props hub, and use our MLB park factors page to compare venue impacts. Park context matters today: Nationals Park and Yankee Stadium are two of the clearest power boosts on the board, while pitcher-friendly parks like Busch Stadium, Oracle Park, and loanDepot park demand more selective targeting.

Below, we break down the best home run odds and prop picks across today’s slate, focusing on batter upside, matchup context, and ballpark power factors. You can also browse our broader MLB props coverage for additional betting markets beyond home runs.

Top Home Run Prop Picks for Today’s Slate

Hunter Goodman (+291) — Rockies vs. Nationals

The data points heavily toward the matchup in Washington tonight, making Hunter Goodman an incredibly appealing target. While specific season-long power metrics are unavailable in today’s dataset, this pairing provides massive upside.

Goodman’s formidable underdog mentality shines when facing a vulnerable pitch-to-contact arm. He faces Nationals starter Matt Waldron, who has surrendered a 1.70 HR/9 rate this season. That stands as the second-highest mark among all starting pitchers taking the mound today.

Nationals Park is one of the premier environments for power hitters. The stadium yields an average of 3.09 home runs per game and ranks fifth overall in runs scored at 11.11 per contest. Attacking a severely home-run-prone pitcher in a top-tier park is exactly the formula required for a high-leverage prop play.

CJ Abrams (+321) — Nationals vs. Rockies

Staying within the exact same game, we flip dugouts to target CJ Abrams against the Rockies’ pitching staff. Similar to Goodman, Abrams lacks specific isolated power (ISO) metrics in the current dataset, but this play is entirely driven by optimal matchup volume. Abrams steps into the box against Colorado starter Tanner Gordon, who currently holds a disastrous 1.88 HR/9 rate. That is the absolute highest home-run-allowed rate of any starting pitcher on today’s slate.

Taking Abrams to exploit the slate’s most vulnerable pitcher in the power-friendly confines of Nationals Park is a highly logical bet. The ballyhooed shortstop has the raw athletic tools and grinding work ethic to punish mistakes over the plate. At 3.09 combined home runs per game, this venue elevates every fly ball.

Yordan Alvarez (+268) — Astros vs. Yankees

For our third pick, we look to the heavyweight American League clash in the Bronx. Because the Yankees’ starting pitcher is currently listed as TBD, we cannot evaluate a specific pitcher’s HR/9 rate or lean on career batter-versus-pitcher statistics. However, targeting a premium, high-volume slugger like Alvarez at Yankee Stadium remains a fundamentally sound DFS and betting strategy.

The venue notoriously favors power hitters, especially left-handed bats, averaging an elevated 2.71 home runs per game. Betting on a reliable power bat to clear the fences in an environment built for home runs provides a formidable anchor for today’s betting card. Alvarez does not need a favorable pitching matchup to showcase his raw power, making him a safe, high-leverage investment on this massive slate.

Shohei Ohtani (+261) — Dodgers vs. Braves

Ohtani is the final add to the card because he combines the shortest home run price in Dodgers-Braves with the kind of one-swing upside that plays in any park. DraftKings has him at +261, with FanDuel and WilliamHillNewJersey both sitting slightly shorter at +255, which keeps the DraftKings number as the best available price in the current market.

Truist Park is not quite as explosive as Nationals Park or Yankee Stadium, but it is still a viable power setting, averaging 2.47 home runs and 8.82 runs per game this season. In a marquee matchup loaded with power bats, Ohtani is the best way to get direct exposure to the Dodgers’ highest-ceiling slugger without needing to chase a longer-shot profile.