MLB Opening Day Pitching Matchups and Starting Lineups
By Sascha Paruk in MLB Baseball
Published:
- The Opening Day pitching matchups and batting orders have been set
- Only seven games are on the Opening Day schedule, which starts at 2:20 pm ET
- Below, see the Opening Day starting pitchers and batting orders for all games
The 2022 MLB season starts today with the Milwaukee Brewers vs Chicago Cubs at 2:20 pm ET. Two games were postponed (Yankees vs Red Sox and Mariners vs Twins) leaving just seven games on the schedule for April 7.
The starting lineups and pitching matchups can be found below. This page will be updated throughout the day as more lineups become official.
Jump to: Brewers vs Cubs | Guardians vs Royals | Pirates vs Cardinals | Mets vs Nationals | Reds vs Braves | Astros vs Angels | Padres vs D-Backs
Brewers vs Cubs Starting Lineups
| Position | Player | Player | Position |
|---|---|---|---|
| 2B | Kolten Wong | Rafael Ortega | DH |
| SS | Willy Adames | Nick Madrigal | 2B |
| LF | Christian Yelich | Willson Contreras | C |
| DH | Andrew McCutchen | Ian Happ | LF |
| 1B | Rowdy Tellez | Frank Schwindel | 1B |
| RF | Hunter Renfroe | Seiya Suzuki | RF |
| C | Omar Narvaez | Jason Heyward | CF |
| CF | Lorenzo Cain | Patrick Wisdom | 3B |
| 3B | Jace Peterson | Nico Hoerner | SS |
| Pitcher | Corbin Burnes | Kyle Hendricks | Pitcher |
Notes:
- Reigning NL Cy Young-winner Corbin Burnes gets the start for Milwaukee. He starts the 2022 season as the second-favorite in the NL Cy Young odds.
- Cubs Japanese import Seiya Suzuki is favored in the NL Rookie of the Year odds.
- Milwaukee is a -175 favorite in the Brewers vs Cubs odds today.
Guardians vs Royals Starting Lineups
| Position | Player | Player | Position |
|---|---|---|---|
| CF | Myles Straw | Whit Merrifield | RF |
| LF | Ahmed Rosario | Bobby Witt Jr | 3B |
| 3B | Jose Ramirez | Andrew Benintendi | LF |
| DH | Franmil Reyes | Salvador Perez | C |
| 1B | Bobby Bradley | Carlos Santana | 1B |
| 2B | Yu Chang | Hunter Dozier | DH |
| RF | Steven Kwan | Adalberto Mondesi | SS |
| C | Austin Hedges | Michael A Taylor | CF |
| SS | Andres Gimenez | Nicky Lopez | 2B |
| Pitcher | Shane Bieber | Zack Greinke | Pitcher |
Notes:
- Cleveland starter Shane Bieber is back in action after managing just 96.2 innings last season. He is the second-favorite in the AL Cy Young odds, trailing only New York’s Gerrit Cole.
- Royals 3B Bobby Witt Jr starts the 2022 season as the favorite in the AL Rookie of the Year odds.
- KC finds itself a +107 home underdog on Opening Day in the Guardians vs Royals odds.
Pirates vs Cardinals Starting Lineups
| Position | Player | Player | Position |
|---|---|---|---|
| DH | Daniel Vogelbach | Dylan Carlson | RF |
| CF | Bryan Reynolds | Paul Goldschmidt | 1B |
| 3B | Ke’Bryan Hayes | Tyler O’Neill | LF |
| 1B | Yoshi Tsutsugo | Nolan Arenado | 3B |
| SS | Kevin Newman | Albert Pujols | DH |
| RF | Cole Tucker | Paul DeJong | SS |
| LF | Ben Gamel | Yadier Molina | C |
| C | Roberto Perez | Harrison Bader | CF |
| 2B | Hoy Park | Tommy Edman | 2B |
| Pitcher | JT Brubaker | Adam Wainwright | Pitcher |
Notes:
- The Pirates and Cardinals start the season a full 21 games apart in the MLB win totals. St Louis’ win total has been set at 85.5. Pittsburgh is at a league-low 64.5.
- St Louis is the biggest favorite of the day, sitting as -210 favorites in the Pirates vs Cardinals odds.
Mets vs Nationals Starting Lineups
| Position | Player | Player | Position |
|---|---|---|---|
| RF | Starling Marte | Cesar Hernandez | 2B |
| DH | JD Davis | Juan Soto | RF |
| SS | Francisco Lindor | Nelson Cruz | DH |
| 1B | Pete Alonso | Josh Bell | 1B |
| 3B | Eduardo Escobar | Keibert Ruiz | C |
| 2B | Robinson Cano | Lane Thomas | LF |
| CF | Mark Canha | Maikel Franco | 3B |
| LF | Jeff McNeil | Alcides Escobar | SS |
| C | James McCann | Victor Robles | CF |
| Pitcher | Tylor Megill | Patrick Corbin | Pitcher |
Notes:
- With Max Scherzer and Jacob deGrom both on the shelf due to injuries, youngster Tylor Megill gets the Opening Day nod for the Mets, who sit sixth in the 2022 World Series odds at +1200.
- Washington’s Juan Soto (+320) is a big favorite in the NL MVP odds, followed by Atlanta’s Ronald Acuna Jr. (+800).
Reds vs Braves Starting Lineups
| Position | Player | Player | Position |
|---|---|---|---|
| 2B | Jonathan India | EddieRosario | RF |
| RF | Aristides Aquino | Matt Olson | 1B |
| LF | Tommy Pham | Austin Riley | 3B |
| 1B | Joey Votto | Marcell Ozuna | LF |
| C | Tyler Stephenson | Ozzie Albies | 2B |
| CF | Nick Senzel | Adam Duvall | CF |
| DH | Mike Moustakas | Travis d’Arnaud | C |
| SS | Kyle Farmer | Alex Dickerson | DH |
| 3B | Brandon Drury | Dansby Swanson | SS |
| Pitcher | Tyler Mahle | Max Fried | Pitcher |
Notes:
- The Atlanta Braves start their quest for a second straight World Series title as the fifth-favorite in the World Series odds, despite losing perennial All Star Freddie Freeman to the Dodgers.
Astros vs Angels Starting Lineups
| Position | Player | Player | Position |
|---|---|---|---|
| 2B | Jose Altuve | Shohei Ohtani | P |
| DH | Michael Brantley | Mike Trout | CF |
| 3B | Alex Bregman | Anthony Rendon | 3B |
| LF | Yordan Alvarez | Matt Duffy | 2B |
| 1B | Yuli Gurriel | Joe Adell | LF |
| RF | Kyle Tucker | Jared Walsh | 1B |
| SS | Jeremy Pena | Max Stassi | C |
| CF | Chas McCormick | Brandon Marsh | RF |
| C | Martin Maldonado | David Fletcher | SS |
| Pitcher | Framber Valdez | Shohei Ohtani | Pitcher |
Notes:
- Reigning AL MVP Shohei Ohtani starts the 2022 MLB season as the favorite in the AL MVP odds, slightly ahead of teammate Mike Trout and Toronto’s Vlad Guerrero Jr.
Padres vs Diamondbacks Starting Lineups
| Position | Player | Player | Position |
|---|---|---|---|
| C | Austin Nola | Daulton Varsho | CF |
| 3B | Manny Machado | Ketel Marte | 2B |
| 2B | Jake Cronenworth | David Peralta | LF |
| DH | Luke Voit | Christian Walker | 1B |
| RF | Wil Myers | Pavin Smith | RF |
| 1B | Eric Hosmer | Carson Kelly | C |
| LF | Jurickson Profar | Seth Beer | DH |
| SS | Ha-Seong Kim | Drew Ellis | 3B |
| CF | Trent Grisham | Geraldo Perdomo | SS |
| Pitcher | Yu Darvish | Madison Bumgarner | Pitcher |
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Sascha Paruk
Managing Editor
Sascha has been working in the sports-betting industry since 2014, and quickly paired his strong writing skills with a burgeoning knowledge of probability and statistics. He holds an undergraduate degree in linguistics and a Juris Doctor from the University of British Columbia.
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