Padres vs Giants Odds, Lines, and Spread – July 29

By Paul Attfield in MLB Baseball
Published:

- The San Diego Padres are off to 4-1 start, tied for joint-best in baseball through the opening week of the season
- Giants starter Johnny Cueto is 8-4 in 15 career starts against San Diego
- Find the odds, matchup analysis and a pick for the game in the article below
After spoiling the San Francisco Giants’ home opener with a 5-3 win on Tuesday night, the San Diego Padres will look to keep that winning feeling going on Wednesday. They should feel confident in doing so, sending right-hander Chris Paddack to the mound to continue his impressive start to the season.
The Giants, who have opened their 2020 campaign by going 2-3, will be hoping to get the ship moving in the right direction. The presence of right-hander Johnny Cueto, who is 8-4 in 15 career starts against San Diego, will give the Giants hope they can do just that when the teams take the field for Game 2 of their three-game set at 9:45 pm ET.
San Diego’s hot start to the season has seen it open as the -166 favorite in the Padres vs Giants odds.
San Diego Padres vs San Francisco Giants Odds
Team | Moneyline | Runline | Over/Under Total at FanDuel |
---|---|---|---|
San Diego Padres | -166 | -1.5 (+100) | O 8 (-104) |
San Francisco Giants | +144 | +1.5 (-118) | U 8 (-118) |
Odds taken July 29
Paddack Finding His Groove
With just 27 career starts, the 24-year-old Paddack is very much still finding his way in his second major league season. The early returns on 2020 have been good, as the right-hander made his first Opening Day start last week, pitching six scoreless innings to set the Padres on course for a comfortable 7-2 win over the Arizona Diamondbacks.
Giants Career Stats vs Paddack
Player | AB | HR | RBI | AVG. |
---|---|---|---|---|
Brandon Crawford | 7 | 0 | 0 | .000 |
Alex Dickerson | 3 | 0 | 0 | .000 |
Mauricio Dubon | 3 | 0 | 0 | .333 |
Wilmer Flores | 5 | 0 | 0 | .400 |
Pablo Sandoval | 5 | 0 | 1 | .500 |
Austin Slater | 1 | 0 | 0 | .000 |
Mike Yastrzemski | 5 | 0 | 0 | .000 |
Due to his age and experience, Paddack has not had a lot of game time against the Giants. He is 1-0 in three career starts with a 2.65 ERA across 17 innings against San Francisco.
Cedar Park product Chris Paddack threw 6 scoreless innings tonight in his first career Opening Day start. Paddack is in line for the win with the Padres up 7-1 in the 8th @CPHS_TWolves @CedarParkBaseb1 #OpeningDay pic.twitter.com/25xQSByxte
— Jeff Barker (@JeffBarker_) July 25, 2020
However, two of those three starts have taken place at Oracle Park, where he picked up his win against the Giants last August, giving up one run over seven innings. In 12 career innings in San Francisco, Paddack has given up four runs in 12 innings for a 3.00 ERA.
After a rough go of it in his prior start, Chris Paddack shone in his outing against the Giants as he helped the @Padres win 5-3 while fanning 8 to move into 8th on this list of SDP rookies (1 off tying for 7th) pic.twitter.com/dEiJPckwCe
— StatsCentre (@StatsCentre) August 30, 2019
After pitching his entire rookie season with five days’ rest between starts, Wednesday’s game will be the first time Paddack has pitched on four days’ rest.
Giants Put Trust In Cueto
After he gave up just one run over four innings on Opening Day, the San Francisco Giants will be hoping for something similar from Johnny Cueto on Wednesday, albeit going deeper into the game. Cueto was pulled after just 63 pitches.
.@JohnnyCueto’s windup just isn’t fair 🤯🔥
(via @SFGiants) pic.twitter.com/4QX8VBPson
— 95.7 The Game (@957thegame) July 24, 2020
Now in his fifth season with San Francisco, the right-hander is 126-87 in his career, with a 3.34 ERA.
Padres Career Stats vs Cueto
Player | AB | HR | RBI | AVG. |
---|---|---|---|---|
Greg Garcia | 5 | 0 | 0 | .200 |
Austin Hedges | 4 | 0 | 1 | .250 |
Eric Hosmer | 6 | 0 | 0 | .333 |
Manny Machado | 9 | 1 | 3 | .222 |
Wil Myers | 19 | 1 | 2 | .158 |
Tommy Pham | 3 | 0 | 0 | .333 |
The last few seasons have been tough physically on the 34-year-old Cueto, who hasn’t made double digits in starts since the 2017 season.
But he has always seemed to enjoy pitching against the Padres, going 8-4 in 15 career starts with a 3.30 ERA and a WHIP of 1.178 in 15 starts against them, with four complete games pitched.
In 38 career starts in San Francisco, both for the Giants and against them, Cueto is 15-10 with a 3.54 ERA.
The @Padres are hitting some loud home runs in San Fran 🔊🔊🔊@wilmyers gets in on the fun in the 4th!#FriarFaithful pic.twitter.com/lOxMm2WvoA
— Bally Sports San Diego (@BallySportsSD) July 29, 2020
Cueto will also look to continue his dominance of Padres slugger Wil Myers. Myers, who hit the game-winning home run in Tuesday’s contest, is just .158 in 19 career at-bats against the Giants right-hander.
Padres on the Rise
With a 4-1 start to the season, confidence is riding high in San Diego, and their recent games against San Francisco should give them hope of continuing that fast start.

The Padres have won three straight against the Giants and four of their last five contests.
However, over the last 10 matchups, the teams are spilt evenly, 5-5.
Pick: Padres (-166); -1.5 (+100)

Sports Writer
For the last 20 years, Paul Attfield has worked in sports media. Starting out in his native Britain with the likes of The Independent, he eventually switched continents, with his work appearing in the likes of the Los Angeles Times, Washington Post and Yahoo Sports since.