Phillies vs Yankees Predictions, Odds & Starting Pitchers (April 5)

• The Yankees are -150 home favorites over the Phillies on Wednesday at Yankee Stadium
• Aaron Nola (0-0, 12.27) will start for the Phillies against the Yankees’ Gerrit Cole (1-0, 0.00)
• A look at the Phillies vs Yankees matchup and odds can be found below with a pick

Fresh off their first win of the season, the Philadelphia Phillies visit the New York Yankees at 1:05 p.m. ET Wednesday in the finale of a three-game series at Yankee Stadium.

The Phillies (1-4. 1-4 road) won 4-1 on Tuesday night after beginning the season with four straight losses. The Yankees (3-2, 3-2 home) had won their previous two games.

Phillies vs Yankees Odds

The New York Yankees are -150 moneyline favorites over the Philadelphia Phillies in the MLB odds, giving them a 60% implied win probability. The Yankees have +700 World Series odds and the Phillies are listed at +1800.

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Phillies vs Yankees Probable Pitchers

Aaron Nola (0-0, 12.27) will pitch for the Phillies against Gerrit Cole (1-0, 0.00). Both will be making their second starts of the season after pitching on opening day last Thursday.

Nola vs Cole

Nola took the loss against the Texas Rangers in Arlington in the opener. He was tagged for five runs in 3.2 innings, allowing four hits, walking two and striking out four.

In three career starts against the Yankees, Nola has a 1-1 record and a 2.37 ERA.

Nola has struggled on the road in his career, posting a 4.10 ERA away from home compared to 3.18 in Philadelphia. His 3.66 ERA in day games is just slightly higher than his night mark of 3.61.

Cole was outstanding in the Yankees’ opener. He struck out 11 over six shutout innings to beat the San Francisco Giants at Yankee Stadium while giving up three hits and two walks.

Gerrit Cole's 11-strikeout day led the Yankees to an #OpeningDay shutout vs. San Francisco. pic.twitter.com/eqZaoJ58oi

— YES Network (@YESNetwork) March 30, 2023

Cole is 5-3 with a 3.12 ERA in eight career starts versus the Phillies.

In 38 career starts at Yankee Stadium, Cole has compiled a 2.94 ERA. That is better than his overall career 3.18 ERA at home, which is slightly better than his 3.26 mark on the road.

Cole, who has +700 AL Cy Young odds, pitches better at night, though. His career ERA is 3.48 during the day and 3.10 under the lights.

Batting Average vs Starting Pitchers

Phillies catcher J.T. Realmuto has worn Cole out over the year, going 11 for 17 (.647) with a home run. Right fielder Nick Castellanos is 7 for 16 (.438) with a double and a triple.

The Yankees quintet of Josh Donaldson, Anthony Rizzo, DJ LeMahieu, Aaron Judge and Giancarlo Stanton have hit a combined .339 batting average off Nola. However, second baseman Gleyber Torres is hitless in nine at-bats, striking out six times.

Judge has +650 AL MVP odds.

Phillies vs Yankees Betting Trends

Kyle Schwarber hit his 200^th career home run and had an RBI single to lead the Phillies to victory Tuesday night.

Kyle Schwarber launches his 200th home run and the Phillies are on the board! 💥

(via @Phillies) pic.twitter.com/jwiXY8F99M

— FOX Sports: MLB (@MLBONFOX) April 4, 2023

Trea Turner, Bryson Stott and Jake Cave had two hits each for the Phillies while Brandon Marsh. The Yankees’ run came on a homer by LeMahieu.

Phillies vs Yankees Last 10 Games

The Phillies hold a slight 10-9 edge in the series since 2010.

Phillies vs Yankees Prediction

Cole was so good on opening day that it’s hard to bet against him. Thus, the Yankees are the way to go.

Pick: Yankees ML (-150)

Season Record: 3-1 (+1.6 units) ML