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New Orleans Saints vs LA Rams Prediction, Spread & Odds for Thursday Night Football Week 16

Robert Duff

by Robert Duff in NFL Football

Updated Dec 21, 2023 · 6:40 AM PST

The Rams are 4-point home favorites over the Saints in the NFL Week 16 TNF game.
Dec 17, 2023; Inglewood, California, USA; Los Angeles Rams quarterback Matthew Stafford (9) drops back to pass against the Washington Commanders during the second half at SoFi Stadium. Mandatory Credit: Gary A. Vasquez-USA TODAY Sports
  • The Los Angeles Rams are 4-point home favorites over the New Orleans Saints in the NFL Week 16 TNF game on Thursday, December 21
  • LA is 6-0 ATS in the club’s last six home games against New Orleans
  • The Saints haven’t won a game SU over the Rams in Los Angeles since 1994. Can they end that streak in the Saints vs Rams picks on Thursday?

Seeking an adjective to effectively describe the performance of the Los Angeles Rams (7-7, 8-5-1 ATS) when at home facing the New Orleans Saints (7-7, 4-9-1 ATS), dominance, is a word that immediately comes to mind. The oddsmakers have taken notice and installed LA as favorites in the Thursday Night Football Saints vs Rams odds.

Los Angeles has won and covered in six successive home games against New Orleans. That winning streak stretches back into the time when they were operating as the St Louis Rams. You have to go all the way back to 1994 to find a game in Los Angeles in which the Saints picked up a win over the Rams to take back home to the Big Easy.

Oddsmakers don’t see that happening this time. It’s LA that’s set as the 4-point home chalk in the Saints vs Rams odds.

Saints vs Rams Odds

Team Moneyline Spread Total
New Orleans Saints +170 +4 (-110) Over 46.5 (-105)
Los Angeles Rams -200 -4 (-110) Under 46.5 (-115)

The Rams are -200 moneyline favorites, giving them a 66.67% implied win probability. The total is set at 46.5 points. The under has hit 16 times in the last 20 games played by the Saints.

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Odds as of Dec. 20 at ESPN BET. Check out our ESPN BET promo before betting on Saints vs Rams and other Week 15 NFL action. And don’t forget to input the promo code “DIME” when signing up at ESPN BET to get your $250 in bonus bets by betting just $10 on this week’s TNF game.

Kickoff at SoFi Stadium on Thursday, December 21, is set for 8:15pm ET. The broadcast is being carried by Prime Video and by DAZN in Canada.

Public Bettors Tailing Rams

The latest NFL public betting splits are in line with the recent history of this matchup. The Rams are pulling 85% of spread handle and 87% of moneyline handle.

Overall the Rams are 8-4 against the spread in the last 12 meetings with the Saints. Against all opponents, LA is 4-1 both straight up and ATS through the past five games. New Orleans is 1-0 ATS as an away underdog this season.

Neither the Rams (6-8) or Saints (4-10) are proving to be effective over plays during the current campaign. However, that factor is trending in the opposite direction of late for LA. The Rams are 3-1 to the over in their past four games.

In the odds to win Super Bowl, Los Angeles is the co-14th betting choice with a line of +10000.  The Saints are at a betting line of +175 to win the NFC South in the NFL divisional odds.

Olave Back for New Orleans

The Saints were able to win 24-6 without WR Chris Olave last week, but that was at home against the pitiful New York Giants. Olave (ankle injury) is trending toward playing in this game and that could prove a big boost for the New Orleans offense.

The second-year WR is the club’s leading receiver. Olave is showing 72 receptions for 918 yards and four touchdowns on his stats sheet this season.

This week should provide a real test for the surging LA offense. The New Orleans defense hasn’t allowed a TD in the last two games while the Saints went 2-0 SU. They checked the Giants on 193 yards of total offense last week.

Rams a Scary Bunch

The health of key players on the LA offense was an issue in the early weeks of the season as the Rams began the campaign 3-6. However, everyone is healthy now, and that’s leaving a sick feeling in the pit of the collective stomachs of LA’s upcoming opponents.

Super Bowl champions just two seasons ago, the Rams have scored 149 points while going 4-1 over the past five games. That makes them the NFL’s #4 scoring offense over that span. QB Matthew Stafford is seventh in the NFL in QBR (62.8), eighth in passing yards per game (255.4) and 10th in TD passes (21).

Two years ago the NFL leader in receptions, receiving yards and TD catches, Rams WR Cooper Kupp was among the walking wounded at the outset of the season. He’s looking more like his old self of late. Kupp has produced consecutive games with at least eight receptions and 100+ receiving yards in the past two weeks and could be worth a play in Thursday’s Saints vs Rams props.

Package them with RB Kyren Williams (936 yards rushing, 11 overall TDs) and rookie sensation WR Puka Nacua (1,163 receiving yards, four TDs) and the Rams are putting a fright into any NFC top seed viewing them as a potential postseason opponent.

Saints vs Rams Prediction

While it’s true that the Saints have won two in a row, they did so at the expense of the Panthers and Giants, not exactly NFL powerhouse squads. Prior to those two games, New Orleans lost three straight and went 2-5 over seven games.

The Rams are a different animal. They’ve recently posted wins over the Browns and Seahawks, while forcing the Ravens to OT in Baltimore.

Saints vs Rams Picks: Rams -4 (-110)

TNF Record: 8-7-0

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