Upcoming Match-ups

NFL Week 3 Odds – Opening Betting Lines & Spreads for All Games

John Perrotto

by John Perrotto in NFL Football

Updated Sep 17, 2023 · 5:21 PM PDT

Dallas Cowboys quarterback Dak Prescott throwing a pass
Dallas Cowboys quarterback Dak Prescott (4) throws a pass at MetLife Stadium. Sunday, September 10, 2023
  • The Giants visit the 49ers on Thursday Night Football to begin NFL Week 3
  • The Chiefs are the biggest NFL Week 3 opening favorites by 12.5 points over the Bears
  • A look at the opening NFL Week 3 odds can be found below with early picks

Week 3 of the NFL season kicks off with the San Francisco 49ers hosting the New York Giants on Thursday Night Football.

The 49ers are 10-point favorites on the opening line in the Week 3 NFL odds after raising their record to 2-0 on Sunday by beating the Los Angeles Rams 30-23. The Giants evened their record at 1-1 by rallying for a 31-28 victory over the Arizona Cardinals.

Sunday Night Football will feature the Pittsburgh Steelers visiting the Las Vegas Raiders. There will again be two games on Monday Night Football with Philadelphia Eagles vs Tampa Buccaneers on ABC and Los Angeles Rams vs Cincinnati Bengals on ESPN.

NFL Week 3 Opening Odds

Team Moneyline Spread Over/Under
New York Giants +380 +10 (-105) Over 42.5 (-110)
San Francisco 49ers -490 -10 (-115) Under 42.5 (-110)
Team Moneyline Spread Over/Under
Los Angeles Chargers -112 -1.5 (+100) Over 51.5 (-110)
Minnesota Vikings -104 +1.5 (-122) Under 51,5 (-110)
Team Moneyline Spread Over/Under
Tennessee Titans +158 +4 (-110) Over 41 (-110)
Cleveland Browns -188 -4 (-110) Under 41 (-110)
Team Moneyline Spread Over/Under
Houston Texans +295 +7.5 (-105) Over 45.5 (-110)
Jacksonville Jaguars -370 -7.5 (-115) Under 45.5 (-110)
Team Moneyline Spread Over/Under
New England Patriots -120 -1 (-110) Over 37.5 (-110)
New York Jets +102 +1 (-110) Under 37.5 (-110)
Team Moneyline Spread Over/Under
New Orleans Saints +102 +1.5 (-110) Over 44 (-110)
Green Bay Packers -120 -1.5 (-110) Under 44 (-110)
Team Moneyline Spread Over/Under
Denver Broncos +210 +6 (-110) Over 46 (-110)
Miami Dolphins -265 -6 (-110) Under 46 (-110)
Team Moneyline Spread Over/Under
Buffalo Bills -290 -6.5 (-110) Over 44 (-110)
Washington Commanders +235 +6.5 (-110) Under 44 (-110)
Team Moneyline Spread Over/Under
Atlanta Falcons +164 +4.5 (-115) Over 45.5(-110)
Detroit Lions -196 -4.5 (-105) Under 45.5 (-110)
Team Moneyline Spread Over/Under
Indianapolis Colts +360 +9.5 (-110) Over 44.5 (-110)
Baltimore Ravens -490 -9.5 (-110) Under 44.5 (-110)
Team Moneyline Spread Over/Under
Carolina Panthers +168 +4.5 (-110) Over 42.5 (-110)
Seattle Seahawks -200 -4.5 (-110) Under 42.5 (-110)
Team Moneyline Spread Over/Under
Dallas Cowboys -560 -10.5 (-115) Over 42.5 (-110)
Arizona Cardinals +420 +10.5 (-105) Under 42.5 (-110)
Team Moneyline Spread Over/Under
Chicago Bears +530 +12.5 (-110) Over 49.5 (-110)
Kansas City Chiefs -750 -12.5 (-110) Under 49.5 (-110)
Team Moneyline Spread Over/Under
Pittsburgh Steelers -126 -1.5 (-110) Over 43.5 (-110)
Las Vegas Raiders +108 +1.5 (-110) Under 43.5 (-110)
Team Moneyline Spread Over/Under
Philadelphia Eagles -300 -6.5 (-115) Over 45.5 (-110)
Tampa Bay Buccaneers +245 +6.5 (-105) Under 45.5 (-110)
Team Moneyline Spread Over/Under
Los Angeles Rams +225 +6.5 (-115) Over 46.5 (-110)
Cincinnati Bengals -275 -6.5 (-105) Under 46.5 (-110)

The Kansas City Chiefs are the biggest NFL Week 3 opening favorites at 12.5 points over the Chicago Bears. The slimmest favorites are the New England Patriots by one point over the New York Jets.

The 51.5 over/under for Los Angeles Chargers vs Minnesota is the highest on the board. The lowest is 37.5 for Patriots vs Jets.

 

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Odds as of September 17th at FanDuel. Claim a FanDuel promo code to wager on the NFL’s Week 3 games and check out FanDuel Kentucky if you are a KY resident. 

Chargers vs Vikings Opening Odds & Prediction

Two teams that reached the playoffs last season find themselves in 0-2 holes to start 2023 when they meet at 1 p.m. ET Sunday at U.S. Bank Stadium in Minneapolis. The Chargers are 1.5-point favorites.

The Chargers lost to the Titans 27-24 in overtime on Sunday as Nick Folk kicked a game-winning 41-yard field goal in a downpour. Justin Herbert threw for 305 yards and two touchdowns to Keenan Allen, but Los Angeles fell to 0-2 for the first time since 2017.

The Vikings lost four fumbles on Thursday night while losing 34-28 to the Philadelphia Eagles. Kirk Cousins rallied Minnesota from a 27-7 deficit in the third quarter as he finished with 364 passing yards, but the comeback fell six points short.

The Vikings’ 13-4 regular-season record in 2022 had a fluky feel to it as they gave up more points than they scored. It seems like things are catching up to Minnesota this season.

Pick: Chargers -1.5 (+100)

Broncos vs Dolphins Opening Odds & Prediction

The Miami Dolphins (1-0) are favored by six points at home over the Denver Broncos (0-2) in a game set for 1 p.m. ET Sunday at Hard Rock Stadium in Miami Gardens, Fla.

Hiring Sean Payton as coach has not provided the Broncos with the boost they were hoping for as they have lost their first two games by a combined three points. They fell to the Commanders 35-33 on Sunday when Russell Wilson threw a 50-yard touchdown pass to Brandon Johnson as time expired to draw the Broncos with two points.

However, Washington’s defense bent but didn’t break by stopping what would have been the tying two-point conversion attempts.

The Dolphins visited the New England Patriots on Sunday night after outlasting the Chargers 36-34 in Week 1.

The Broncos have a tall task ahead after starting 0-2. They will have a hard time keeping things so close against the explosive Dolphins.

Pick: Dolphins -6 (-110)

Movement On The Line?

The Dallas Cowboys (2-0) are big favorites over the Arizona Cardinals (0-2) with the line opening at 10.5 points for the 4:25 p.m. ET Sunday game at State Farm Stadium in Glendale, Ariz.

The Cowboys have outscored their first two opponents 70-10 after downing the New York Jets 30-10 on Sunday. The Cardinals blew a 21-point lead in the third quarter while falling to the New York Giants 31-28.

Though the spread is substantial, it still seems a little light considering the formidable Cowboys defense will be facing Cardinals backup quarterback Joshua Dobbs. Jump on the Cowboys early before the line moves upward.

Pick: Cowboys -10.5 (-115)

 

 

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