Opening NFL Week 11 Odds – Spread, Total, Moneyline for All 14 Games

• Odds are out for NFL Week 11
• Week 11 starts with a huge NFC East battle between the Eagles and Commanders on TNF
• See the NFL Week 11 odds (spread, moneyline, and total) for all 14 games

Another NFL Sunday is almost done and dusted, which means oddsmakers have posted lines for the next batch of games. NFL Week 11 starts with a massive game in the NFC East between the Philadelphia Eagles (7-2) and Washington Commanders (7-3) on Thursday, which will be followed by a 12-game slate on Sunday and an all-Texas battle between the Houston Texans (6-3) and Dallas Cowboys (3-6) on Monday Night Football. The table belows lists the opening NFL Week 11 odds for all 14 games.

Opening NFL Week 11 Odds

The Arizona Cardinals (6-4), Carolina Panthers (2-7), New York Giants (2-7), and Tampa Bay Buccaneers (4-5) are on bye on Week 11.

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After a blocking a last-second field goal against the Denver Broncos (5-5), the still-undefeated Kansas City Chiefs (9-0) remain the favorites in the Super Bowl 59 odds (+399 on average).

Biggest NFL Week 11 Point Spread: Jaguars vs Lions (-12.5)

The biggest spread of Week 11 isn’t even close. The Detroit Lions (7-1) are laying 12.5 points at home to the Jacksonville Jaguars (2-8). Heading into its Week 10 SNF battle with Houston, Detroit had won six straight by an average of 18 points per game while averaging 36.0 PPG. The Lions have hit 40 points in three of their last four and put up 52 on the Titans in Week 8, the highest by any team in the league this season.

The Jaguars, meanwhile, have lost three straight and have yet to win a true road game this season. Their first win came at home against Indianapolis (37-34) on a last-second field goal in Week 5. Their other was a 32-16 victory over New England in London in Week 7. Replacing the injured Trevor Lawrence, Mac Jones and the offense looked horrendous in Week 10, falling 12-7 at home to Minnesota. Yes, the Vikings have one of the league’s best defenses, but the Jags managed just 143 yards of total offense. That’s an average of just 35.8 yards per quarter.

#Jaguars lose without allowing a TD 12-7 to Vikings. How? Jags offense: Three turnovers, 10 first downs, 143 yards (fifth lowest in franchise history). Jags ran 43 plays to Minnesota's 80. Jags had ball for 17:36 to 42:19 for Vikings. Inept in every way.

— Hays Carlyon (@HaysCarlyon) November 10, 2024

Highest NFL Week 11 Total: Seahawks vs 49ers (49.5)

The highest Week 11 total comes in the NFC West battle between the Seattle Seahawks (4-5) and San Francisco 49ers (5-4) on Sunday afternoon. The Commanders/Eagles game also has a total of 49.5, but it’s juiced to the under (-115) while the Seahawks/Niners total is -110 both ways.

These teams combined for 60 points when they met in Week 6 during a 36-24 San Francisco victory. The 49ers also got Christian McCaffrey back in Week 10, which has pundits predicting bigger and better things for their offense. McCaffrey was held to just 39 rushing yards on 13 carries in a 23-20 win over Tampa Bay, though the dual-threat added another 68 yards on six receptions.

Seattle is coming off a Week 10 bye,

Lowest NFL Week 11 Total: Vikings vs Titans (41.5)

The lowest total in the Week 11 NFL odds is the Minnesota Vikings (7-2) vs Tennessee Titans (2-6), which has opened at 41.5. Minnesota is 3-6 over/under this season and has played in two particularly low-scoring games the last two weeks: in Week 9, they earned a 21-13 win at Indianapolis and, as mentioned above, in Week 10, took a 12-7 win at Jacksonville (without scoring a TD).

The Titans are 5-3-1 O/U but have only scored more than 20 points once all season (a 31-12 win over Miami in Week 4). Earlier today, they fell 27-17 at the Chargers.