- Italians seek a second straight European final appearance at 3:00 pm ET on Thursday in Germany
- Roma holds a 1-0 lead from the first leg in Italy with both teams struggling domestically
- See our Bayer Leverkusen vs AS Roma prediction, odds and best bets for the Europa League semifinals second leg
Two teams struggling for domestic form switch to Europa League semifinal second-leg action and we have your Bayer Leverkusen vs AS Roma prediction for Thursday’s match here.
Italian giant Roma holds a slender 1-0 lead from the first leg.
Under superstar coach Jose Mourinho, it is seeking a second successive European trophy after winning the inaugural Europa Conference League last season.
However, it has not won in five Serie A matches and Mourinho says his men are tired.
Furthermore, Bayer Leverkusen is without a win in three Bundesliga fixtures.
Sevilla meets Juventus (1-1) in the other semifinal with the final to decide the Europa League winner in Budapest on May 31.
Bayer Leverkusen vs Roma Odds
At Draftkings, Bayer Leverkusen is the favorite for a win in this tie at +105 in the Leverkusen vs Roma odds above. With kick-off at 3:00 pm ET, Roma is priced at +280. Meanwhile, the draw after 90 minutes is rated at +240.
Meanwhile, Roma is the second favorite to win the competition at +260 – behind favorite Sevilla at +225 in the Europa League odds.
Moreover, Xabi Alonso’s Bayer Leverkusen outfit is the competition outsider at +300 behind third-placed Juventus, which is priced at +275.
Odds as of May 17 at DraftKings Sportsbook.
Bayer Leverkusen vs Roma Over/Under & Spread
After a tight first leg, there is a need for goals the second time around.
Therefore, the offer for there to be at least three goals stands at +115 (Over 2.5) in the Bayer Leverkusen vs AS prediction.
Further up the scale, there is a price of +300 for four goals or more (Over 3.5).
💬 @XabiAlonso: „We are happy to reach the semifinals, but we want more!“
— Bayer 04 Leverkusen (@bayer04_en) May 17, 2023
At the narrow end of the scale, there is a price of +215 for just one goal during 90 minutes (Under 1.5).
Among the spread offers, Bayer Leverkusen is rated at +290 to win by two goals (Spread -1.5).
Meanwhile, Roma is priced at +250 to win by a solitary goal (Spread -0.5).
Bayer Leverkusen vs Roma Preview
Roma midfielder Edoardo Bove struck the winner in the first leg in the Italian capital.
However, it has lost twice on its travels in the Europa League group stage – and again in knockout ties at Red Bull Salzburg and Feyenoord, although it has still progressed.
It lost 1-0 at Feyenoord in the quarterfinal first leg. However, it stormed back with a 4-1 victory at home.
Mourinho’s side has slumped in the league recently and is in sixth place. The 0-0 draw at Bologna marked a current run of three draws and two defeats.
So the Champions League place on offer for the Europa League winner may offer its only chance of European action next season.
The same is true for seventh-placed Bayer Leverkusen, which has a recent run of two draws and a defeat in recent Bundesliga action.
It dropped down from the Champions League and was a quarterfinal Europa League winner over Union St Gilloise.
After a 1-1 draw at home, it hit European form similar to Roma and won the return leg 4-1.
In this clash, Bayer Leverkusen will seek to cash in on the vulnerability Roma has shown on the road in this competition – with the German side having won five of its last seven home dates.
However, the Romans’ coach Mourinho is a master at European strategy and is unlikely to allow another such slip-up away from home.
Bayer Leverkusen vs Roma Statistics
*Statistics from UEL 2022-23.
Sardar Azmoun to Score Odds
Bayer Leverkusen’s Iranian striker Sardar Azmoun is the joint favorite to be on target at +275. To score first or last, he is priced at +600.
However, he has not scored in six Europa League appearances this season. And he has only four Bundesliga goals in 21 games.
Out for final training session! ⚫️🔴
— Bayer 04 Leverkusen (@bayer04_en) May 17, 2023
Meanwhile, his teammate Moussa Diaby is jointly priced with Azmoun. But he has a more impressive record of three Europa League goals and nine Bundesliga strikes.
Furthermore, Roma’s leading scorer is the Argentine Paolo Dybala.
With four Europa League goals and 11 in Serie A, he is rated at +300 to score this time out – and at +650 to score first or last. However, he may suffer some after effects of an ankle injury.
Bayer Leverkusen vs Roma History
Before the first leg of this tie, these teams let met in the UCL group stage in season 2015-16.
There was a 4-4 draw in Germany followed by a 3-2 win for Roma in Italy.
Bayer Leverkusen vs Roma Line-Ups & Injuries
Bayer Leverkusen projected line-up: Hradecky; Tapsoba, Tah, Hincapie; Frimpong, Demirbay, Palacios, Bakker; Diaby, Wirtz, Azmoun
Bayer Leverkusen Injuries: Andrich, Schick, Lunev
Roma projected line-up: Patricio; Mancini, Cristante, Ibanez; Celik, Matic, Bove, Spinazzola; Dybala, Wijnaldum; Abraham
Roma Injuries: El Sharaawy, Llorente
Bayer Leverkusen vs Roma Prediction
Roma coach Jose Mourinho is an old hand at this sort of thing and is highly capable of masterminding a narrow win. So the spread offer of a one-goal victory for the Italians looks attractive for our Bayer Leverkusen vs AS Roma prediction.
Leverkusen vs Roma Picks: Roma +250 (Spread -0.5.)