Padres vs Phillies Odds, Lines, and Spread (May 19)

By Chris Amberley in MLB Baseball
Published:

- The Padres vs Phillies odds favor Philadelphia as -120 moneyline favorites on Thursday (May 19, 1:05 pm ET)
- San Diego will send Yu Darvish 3-1, 4.62 ERA) to the mound, while Philly will counter with Kyle Gibson (3-1, 4.10 ERA)
- Read below for the Padres vs Phillies odds, analysis and betting prediction
San Diego and Philadelphia will close out a three-game series on Thursday afternoon in the city of Brotherly Love. The Phillies rebounded from a 3-0 defeat in the series opener on Tuesday, posting a 3-0 victory of their own on Wednesday.
The win snapped a three-game losing streak for Philadelphia, and oddsmakers are expecting them to keep the momentum going in the series finale.
Padres vs Phillies Odds
Team | Moneyline | Runline | Total |
---|---|---|---|
San Diego Padres | +100 | +1.5 (-180) | O 8.0 (-115) |
Philadelphia Phillies | -120 | -1.5 (+155) | U 8.0 (-105) |
Odds as of May 18th at Caesars Sportsbook.

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The Phillies opened up as -120 moneyline favorites, in a contest that features a total of 8 runs. First pitch is scheduled for 1:05pm ET at Citizens Bank Park in Philadelphia, PA, with cloudy skies and 76 degree temperatures in the forecast.
San Diego vs Philadelphia Pitchers
The Padres, a top-10 contender in the World Series odds, will give the ball to veteran Yu Darvish. The 35-year-old is coming off his worst start of the season, where he surrendered nine hits and five runs to Atlanta.
Yu Darvish, Nasty Sliders and 97mph 🔥 pic.twitter.com/zByZlhISso
— Rob Friedman (@PitchingNinja) May 14, 2022
Darvish had pitched very well in his previous three starts, a stretch that includes 6 innings of shutout ball against the Dodgers.
He’s 1-1 in five career starts against the Phillies, and has limited the current Philadelphia roster to a .244 slugging percentage and .435 OPS over 74 at-bats
Darvish vs Gibson
3-1 | Record | 3-1 |
4.62 | ERA | 4.10 |
1.18 | WHIP | 1.21 |
.235 | OBA | .232 |
2.9 | SO/W Ratio | 2.3 |
The Phillies will turn to Kyle Gibson, who’s also coming off his worst outing of the year. Gibson allowed eight hits and six runs over 3.2 innings last week versus the Dodgers, which snapped a stretch of three solid starts.
He’s 2-0 in three career outings against the Padres, holding the San Diego roster to a .317 slugging percentage and .634 OPS.
Padres vs Phillies Betting Analysis
The San Diego lineup has actually been quite disappointing despite their 23-14 record. They rank ninth in runs, but bottom-11 in MLB in batting average, slugging and OPS. Things would be a lot worse if not for the play of Manny Machado and Eric Hosmer.
Manny Machado showing up in the clutch 🥶😎#TimetoShine | @Padres pic.twitter.com/inMLfBotZ5
— Bally Sports San Diego (@BallySportsSD) May 11, 2022
The duo rank second and third in MLB in batting average, while Machado is currently the favorite in the NL MVP odds. San Diego’s lineup will look much different once All-Star Fernando Tatis returns, but he’s still recovering from offseason wrist surgery.
Philadelphia meanwhile, should get reigning MVP Bryce Harper back on Thursday. Harper has missed the last three games after getting a PRP injection for his injured right elbow, and the Phillies have averaged only 2.3 runs per outing in his absence.
It's time to have that conversation.
We're staring down another MVP-level campaign from Bryce Harper right now.
He's hitting .302 alongside a .995 OPS. He leads the Phillies with 9 home runs, and he has gone ballistic of late.
Manny Machado will be tough to beat, but wow.
— Alex Carr (@AlexCarrMLB) May 15, 2022
Before sitting out the early part of this week, Harper ranked first in MLB in home runs, slugging, runs and doubles, and second in OPS and RBI. The rest of the Philadelphia lineup has been a mixed bag, but fuelled by Harper, they still rank top-six in runs, batting average, slugging and OPS.
SD vs PHI Last 10 Meetings
Date | Away Team | Home Team | Score |
---|---|---|---|
5/18/22 | Padres | Phillies | PHI, 3-0 |
5/17/22 | Padres | Phillies | SD, 3-0 |
8/22/21 | Phillies | Padres | PHI, 7-4 |
8/21/21 | Phillies | Padres | SD, 4-3 |
8/20/21 | Phillies | Padres | PHI, 4-3 |
7/4/21 | Padres | Phillies | SD, 11-1 |
7/3/21 | Padres | Phillies | PHI, 3-2 |
7/2/21 | Padres | Phillies | PHI, 4-3 |
8/17/19 | Padres | Phillies | PHI, 3-2 |
8/16/19 | Padres | Phillies | PHI, 5-3 |
Padres vs Phillies Pick
With Harper likely coming back and Gibson and Darvish fresh off horrible outings, there’s plenty of reasons to like the over in this matchup.
Also working in favor of the over is an underwhelming bullpen for both clubs. San Diego and Philadelphia relievers each rank in the bottom-nine in MLB in ERA and strand rate, which has led to a number of high scoring games.
Twelve of the Padres 20 road games have exceeded the total, while the over is 19-16-2 in Phillies contests this season. Three of Gibson’s last five starts have produced double-digit runs, while two of Darvish’s last three outings have as well.
Pick: Over 8.0 Runs (-115)
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Sports Writer
As SBD's resident Swiss Army Knife, Chris covers virtually every sport including NFL, PGA, NBA, MLB, NCAAB, NCAAF and the Olympics. A true grinder, he'd rather pick off small edges in the player props market than swing for the fences with a 5-leg parlay.