Astros vs Phillies World Series Predictions, Odds & Schedule

By Robert Duff in MLB Baseball
Updated: October 24, 2022 at 2:54 pm EDTPublished:

- The Houston Astros are -200 favorites in the World Series odds over the Philadelphia Phillies
- It’s the second straight season and fourth out of six that the Astros have reached the World Series
- Below, see the Astros vs Phillies predictions and World Series odds
The Philadelphia Phillies (9-2, 4-2 away) have been very good en route to their first World Series appearance in more than a decade. However, in getting back to the Fall Classic for the second time in as many years, the Houston Astros (7-0, 4-0 home) are the picture of perfection.
Playing in the World Series for the fourth time over the past six seasons, the Astros are set as solid -200 favorites in the World Series odds over the Phillies. Philadelphia is in baseball’s Fall Classic for the first time since 2009.
Astros vs Phillies World Series Odds
Team | Moneyline |
---|---|
Houston Astros | -200 |
New York Yankees | +175 |
Odds as of October 24 at FanDuel Sportsbook. Get Caesars Sportsbook bonus code.
At moneyline odds of -200, the Astros have an implied probability of victory of 66.67% in the MLB betting line. A successful $100 wager on Houston would create a payout of $150.00.

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In the MLB playoff bracket, Game 1 at Minute Maid Park goes Friday, October 28 at a time TBD. FOX Sports is carrying the broadcast of the series in the USA, while Canadians can watch on Sportsnet.
Houston vs Philadelphia H2H Results
The Astros and Phillies clashed in a three-game regular-season series Oct. 3-5. Houston won two of three games, outscoring Philadelphia 13-5.
FINAL: Astros 6, Yankees 5
The Houston Astros are going to the World Series, and they still haven't lost a game this postseason. A comeback win capped their sweep of the Yankees, whose World Series drought is now 13 seasons.
Astros-Phillies, Game 1, Friday at Minute Maid Park.
— Jeff Passan (@JeffPassan) October 24, 2022
They’ve met one time previously in the playoffs, when both clubs were in the National League. In the 1980 NLCS, the Phillies beat the Astros 3-2 en route to winning the World Series in seven games over the Kansas City Royals.
Astros vs Yankees ALCS Schedule
Date (Time) | Game | TV |
---|---|---|
Oct. 28 (TBD) | Philadelphia Phillies @ Houston Astros | FOX, Sportsnet |
Oct. 29 (TBD) | Philadelphia Phillies @ Houston Astros | FOX, Sportsnet |
Oct. 31 (TBD) | Houston Astros @ Philadelphia Phillies | FOX, Sportsnet |
Nov. 1 (TBD) | Houston Astros @ Philadelphia Phillies | FOX, Sportsnet |
Nov. 2 (TBD) | Houston Astros @ Philadelphia Phillies* | FOX, Sportsnet |
Nov. 4 (TBD) | Philadelphia Phillies @ Houston Astros* | FOX, Sportsnet |
Nov. 5 (TBD) | Philadelphia Phillies @ Houston Astros* | FOX, Sportsnet |
*If necessary
Houston’s Dusty Baker has won pennants as a manager in both the NL and AL. He won a World Series as a player with the 1981 Los Angeles Dodgers. However, he’s won the most games (2,093) of any MLB manager without winning a World Series.
In the NLDS, the Phillies eliminated the Atlanta Braves. Last season, the Braves beat the Astros in the World Series.
Astros vs Phillies Betting Trends
Houston is #3 in the AL with an 89-79 record against the runline this season. The Phillies are 89-84. Only three MLB clubs have won more often ATS.
Y'all wanted us, y'all got us. pic.twitter.com/a7vY5Tuh4W
— Houston Astros (@astros) October 24, 2022
Philadelphia was 2-1 against the runline facing the Astros this season. The two teams were 1-2 against the total.
Houston vs Philadelphia Probable Pitchers
Since the World Series doesn’t get underway until Friday, both teams can set up their pitching rotation any way manner they so choose. In the MLB lineups, ace right-hander Justin Verlander, the chalk in the AL Cy Young odds, figures to be getting the ball for Game 1. Verlander, 39, led the AL with 18 wins.
It’s a Phillies-Astros World Series
Probably Wheeler-Verlander in G1, Nola vs. Framber Valdez G2 — tremendous matchups
Astros won 106 games & have enough pitching to fill 2 rotations. But this is a race to 4 wins & the Phillies feel like they can beat anyone anywhere right now
— Corey Seidman (@CSeidmanNBCS) October 24, 2022
The Astros can then follow with Framber Valdez, Lance McCullers Jr and Cristian Javier.
In Philadelphia’s case, expect the Phillies to launch with the 1-2 punch of Zack Wheeler and Aaron Nola. They’ll likely go next with Ranger Suarez and Bailey Falter.
Phillies vs Astros Team Stats
Pitching is what the Astros are all about. This season Houston was the only AL staff to post an ERA under 3.00 (2.90) and a WHIP under 1.10 (1.09). The Astros were second in MLB in both of these categories, as well as in batting average allowed (.212). As well, the bullpen chalked up an AL-best 53 saves.
ASTROS. PHILLIES.
The World Series is SET 🏆 pic.twitter.com/YlpClompPZ
— ESPN (@espn) October 24, 2022
In the ALCS against the Yankees, Houston’s starting rotation allowed four earned runs over 23.1 innings of work. The Astros bullpen surrendered two earned runs over 12.2 innings. As well, Houston pitchers struck out 50 Yankees batters. During the regular season, the Astros clouted 214 home runs to finish second in the AL.
Phillies vs Astros
87-75 | W-L | 106-56 |
6 | Playoff Seeding | 1 |
747 | Runs Scored | 737 |
209 | Home Runs | 214 |
.253 | AVG | .248 |
.739 | OPS | .743 |
3.97 | ERA | 2.90 |
1.26 | WHIP | 1.09 |
Philadelphia slugged 209 homers this season. In the postseason, Phillies pitchers are showing a staff ERA of 3.06 and a WHIP of 0.97. However, both of those numbers still trail the Astros (1.88 ERA, 0.93 WHIP).
The Phillies have also clouted a playoff-leading 16 long balls. Philadelphia’s .749 OPS is second among postseason squads.
Astros vs Phillies World Series Prediction
Houston is just the fourth team to open the MLB postseason 7-0. The most recent was the 2020 Braves, who didn’t make it to the World Series.
the Phillies won 19 fewer regular-season games than the Astros
that’s the 2nd-largest RS wins diff in a World Series, behind only 1906, when the White Sox won 23 fewer than the Cubs
CHW won that series
— Sarah Langs (@SlangsOnSports) October 24, 2022
The Astros join the 2007 Colorado Rockies and 2014 Kansas City Royals as the third team to sweep to the World Series with. 7-0 slate. However, both of those teams lost the World Series.
Everything points to the Astros winning this series. And yet the Phillies look so much like a team of destiny.
Best Bet: Philadelphia Phillies ML (+175)

Sports Writer
An industry veteran, Bob literally taught the course on the history of sports at Elder College. He has worked as a Sports Columnist for Postmedia, appeared as a guest on several radio stations, was the Vice President of the Society For International Hockey Research in Ontario, and written 25 books.