Twins vs Nationals Predictions, Best Bets & Props

• The Twins battle the Nationals in the rubber match of their series Thursday, May 7th
• Simeon Woods Richardson and Jake Irvin will start in a battle of struggling pitchers
• Keep reading to see my Twins vs Nationals picks and predictions and the latest odds

The Minnesota Twins (16-21) and Washington Nationals (17-20) complete their series for a getaway game Thursday afternoon, with each team posting one victory in the first two duels. First pitch scheduled for 1:05 PM ET / 10:05 AM PT at Nationals Park and the Nats are favorites in the MLB odds.

In the previous matchup, the Nationals controlled the game, routing the Twins 15-2. Washington tallied 14 hits and four home runs. That was preceded by a 11-3 first matchup that saw the Twins drub Washington. As both clubs enter this contest looking to climb back toward the .500 mark, I expect a solid skirmish from the home squad.

Twins vs Nationals Picks and Predictions

• Twins vs Nationals Pick: Washington -1.5 Run Line (+170 at Caesars)

With Washington clubbing Minny in their latest outing and the pitching matchup favoring the home side, backing the Nationals on the moneyline is my preferred play. Washington has produced 198 runs this season, fourth most in MLB.

They match up exceptionally well against Minnesota starter Simeon Woods Richardson, who has been scuffling. The Twins hurler has surrendered four or more earned runs in four of five starts, failing to make it past five innings.

Woods Richardson is still searching for his first win of the season and has struggled heavily to suppress offensive damage. He enters with a 1.76 WHIP and a meager 4.41 K/9. When batters make contact, he yields 12.20 hits and 2.08 home runs per nine innings, leading to a ghastly .324 opponent batting average.

For the Nationals, Jake Irvin has experienced plenty of hard luck this season, but his 4.04 FIP indicates he has pitched significantly better than his 4.93 surface ERA suggests. His primary weapon is missing bats, boasting an excellent 10.12 K/9 rate. He has limited opponents to a .224 batting average despite occasional command issues.

In front of their home crowd, Washington plates 5.17 runs per game on 8.00 hits, outpacing the Twins’ road production of 4.59 runs and 7.06 hits per contest.

• Player Prop Bet: Simeon Woods Richardson Under 3.5 Strikeouts (+100 at BetMGM)

For player prop value, I am targeting Woods Richardson to go under 3.5 total pitcher strikeouts at +100 odds at BetMGM. Given his elevated WHIP and pitch-to-contact profile, it is highly unlikely he pitches deep enough into this contest to accumulate four strikeouts. Additionally, SWR has failed to crack four K’s in six of seven starts on the campaign.

Twins vs Nationals Odds and Betting Splits

Odds as of May 7, 2026, at 11:17 AM ET from Caesars. Click here for a Caesars Sportsbook promo code before betting on Twins vs Nationals.

In the MLB public betting splits, 56% of bets and 58% of cash from the public is on the Nats. 65% for both wagers and money is on Washington to win on the run line, which I selected for my bet. Finally, 84% of the action and 82% of mula is on over nine combined runs being scored.

Nationals vs Twins Injury Report

How to Watch Twins vs Nationals

TV Network: Twins.TV and Nationals.TV

Away Team: Minnesota Twins

Home Team: Washington Nationals

Date: May 7, 2026

Game Time: 1:05 PM ET / 10:05 AM PT

Venue: Nationals Park

Location: Washington, DC