Astros vs Orioles Picks & Odds (Sep. 25)

By John Perrotto in MLB Baseball
Published:

- The Astros are -159 road favorites over the Orioles on Sunday
- Cristian Javier (10-9, 2.77) will start for Houston against Austin Voth (5-3, 4.32)
- A look at Astros vs Orioles odds can be found below with a pick
The American League West champion Houston Astros will try to gain a split of their four-game series with the host Baltimore Orioles at 1:05 pm ET Sunday at Oriole Park at Camden Yards.
The Astros (100-53/44-30 road) outlasted the Orioles 11-10 on Saturday night for their fifth win in their last seven games and 11th in 13. The Orioles (79-72/43-33 home) had their three-game winning streak end.
The Orioles fell four games behind the Seattle Mariners in the chase for the third and final AL wild card.
Astros vs Orioles Odds
Team | Moneyline | Runline | Total |
---|---|---|---|
Houston Astros | -159 | -1.5 (+107) | Over 8 (-104) |
Baltimore Orioles | +135 | +1.5 (-132) | Under 8 (-115) |
Odds as of September 24th at Barstool Sportsbook. Be sure to check out the Barstool Sportsbook bonuses!
The Astros are -159 favorites, giving them a 61.39% implied win probability. Houston has +425 World Series odds while the Orioles are at +80000.

The weather forecast calls for a 60% chance of showers or thunderstorms about an hour after the game is scheduled to begin. It is also expected to be windy at 13 mph from the southwest with gusts up to 24 mph. The high temperature is forecasted for 81 degrees.
Astros vs Orioles Probable Pitchers
Cristian Javier (10-9, 2.77) is scheduled to pitch for the Astros against Austin Voth (5-3, 4.32). Both will be going on four days of rest.
Javier vs Voth
10-9 | Record | 5-3 |
2.77 | ERA | 4.32 |
2.54 | xERA | 4.33 |
1.00 | WHIP | 1.41 |
3.58 | SO/W | 2.79 |
Javier is 3-0 with a 1.69 ERA in his last four starts, including beating the Tampa Bay Rays on Tuesday in St. Petersburg. He pitched one-hit ball over five scoreless innings while striking out six and walking four.
Cristian Javier. 82-mph slider + 94-mph 4-seam fastball with overlay frozen at the batter’s decision point.
Good luck, Harold!pic.twitter.com/UMKdkOxhMX
— APOLLO MEDIA (@ApolloHOU) September 20, 2022
This will be Javier’s first career start against the Orioles after going 1-0 with a 2.70 ERA in three relief appearances. He has pitched once at Oriole Park at Camden Yards and worked two shutout innings last season.
Javier is 5-4 with a 3.09 ERA in 14 games (12 starts) on the road this season. In day games, he has a 4-2 record and 1.57 ERA in nine appearances (seven starts). The Astros are 13-10 when Javier starts.
Voth is 1-2 in his last five games (four starts) despite a 2.79 ERA.
Voth took the loss Tuesday night against the Detroit Tigers at home. He pitched five innings and gave up two runs and six hits, struck out three and walked none.
In two career games (one start) against the Astros, Voth is 0-1 with a 3.86 ERA.
Voth has an artistic side. Sorta.
I believe this was Austin Voth’s attempt to draw Dean Kremer. pic.twitter.com/eTVdrOOsxM
— Nathan Ruiz (@NathanSRuiz) September 20, 2022
Voth has made nine starts at Camden Yards in 2022 and has gone 3-1 with a 3.79 ERA. He is 1-2 with a sparkling 1.69 ERA in 15 games (nine starts) during the day. The Orioles have a 10-5 record in Voth’s starts.
Batting Average vs Starting Pitchers
Astros Batters | Batting Average vs Austin Voth |
---|---|
David Hensley | .500 |
Trey Mancini | .333 |
Martin Maldonado | .250 |
Jose Altuve | .250 |
Alex Bregman | .000 |
Yuli Gurriel | .000 |
Jeremy Pena | .000 |
Mauricio Dubon | .000 |
Kyle Tucker | .000 |
Yordan Alvarez | .000 |
Orioles Batters | Batting Average vs Cristian Javier |
Kyle Stowers | 1.000 |
Ramon Urias | .333 |
Rougned Odor | .000 |
Jorge Mateo | .000 |
Ryan Mountcastle | .000 |
Cedric Mullins | .000 |
Austin Hays | .000 |
Anthony Santander | .000 |
Adley Rutschman | .000 |
The Astros’ Trey Mancini is 2 for 6 with a double and three strikeouts against Voth, his former teammate with the Orioles.
Astros vs Orioles Betting Outlook
Yuli Gurrriel hit a two-run single to cap a four-run ninth inning as the Astros overcame a 9-7 deficit to win Saturday night. Kyle Tucker drew the Houston into a tie with an RBI double.
STROS TAKE THE LEAD. pic.twitter.com/Krr9knzFLJ
— Houston Astros (@astros) September 25, 2022
Rougned Odor led off the bottom of the ninth with a home run to draw the Orioles within 11-10 but the Astros held on.
Gurriel finished with two hits and three RBIs. The Astros also got two hits each from Yordan Alvarez (+50000 AL MVP odds)and Tucker and two RBIs apiece from Jose Altuve, Jeremy Pena and Alex Bregman.
Altuve hit his 26th home run.
Pena is questionable for Sunday. He left the game with a facial bruise sustained in a play at home plate.
Anthony Santander went deep twice for the Orioles and Cedric Mullins also connected.
Santander and Odor each had three hits and three RBIs. Ryan Mountcastle also had a three-hit game while Adley Rutschman, Ramon Urias and Austin Hays had two each.
TWO HOMERS FOR TONY 🔥🔥 pic.twitter.com/fwb0KCaDoS
— Baltimore Orioles (@Orioles) September 25, 2022
Urias returned to the lineup after missing a game with neck spasms.
The Orioles lead the season series 4-2, including taking two of three in Baltimore.
Astros vs Orioles Last 10 Games
Date | Home Team | Away Team | Score |
---|---|---|---|
9/24/22 | Orioles | Astros | HOU, 11-10 |
9/23/22 | Orioles | Astros | BAL, 6-0 |
9/22/22 | Orioles | Astros | BAL, 2-0 |
8/28/22 | Astros | Orioles | HOU, 3-1 |
8/27/22 | Astros | Orioles | BAL, 3-1 |
8/26/22 | Astros | Orioles | BAL, 2-0 |
6/30/21 | Astros | Orioles | BAL, 5-2 |
6/29/21 | Astros | Orioles | BAL, 13-3 |
6/28/21 | Astros | Orioles | BAL, 9-7 |
6/23/21 | Orioles | Astros | HOU, 13-0 |
Astros vs Orioles Prediction
Javier is on a bit of a roll right now and he figures to keep on going in this one.
Pick: Houston Astros (-159)
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Sports Writer
John Perrotto has been covering and writing about sports for various outlets for over 40 years. His work has appeared in the likes of USA TODAY, ESPN.com, SI.com, Forbes.com, The Associated Press, Baseball Digest, and more. John is based out of Beaver Falls, PA.