Predictions & Expert Picks for Dodgers vs Angels (May 16)

• The Los Angeles Dodgers are the road favorite as they match up with the Los Angeles Angels
• Should you take the Under 8.5 runs because of the two elite starters on the mound?
• You should keep scrolling to see the most up-to-date injury reports, latest odds, and expert picks

---

The Los Angeles Dodgers (26-18) continue their interleague series against the crosstown rival Los Angeles Angels (16-28) at Angel Stadium on May 16, 2026. First pitch is scheduled for 9:38 PM ET.

Following a dominant 6-0 shutout victory in the series opener, the Dodgers bring significant momentum into this matchup. Their offense blasted three home runs, while the pitching staff surrendered just two base hits in a clean defensive performance.

The Angels are desperate for an offensive spark from stars like Mike Trout to climb out of the divisional basement. Conversely, Shohei Ohtani and a potent Dodgers lineup look to maintain their elite production. This game provides compelling angles for bettors to analyze moneyline value and game totals.

Dodgers vs Angels Picks & Predictions

With standard odds available across major sportsbooks, the statistical profiles of both clubs point toward a distinct outcome. The road favorites feature a robust .262 team batting average and .775 OPS, vastly outperforming an Anaheim squad hitting just .228 with a .696 OPS.

• Moneyline Pick: Dodgers ML (-140 at Caesars Sportsbook)

Because of this glaring offensive talent gap, I am backing the Dodgers on the moneyline. Anaheim has struggled significantly when catching plus money, winning just 32.3% of their games as underdogs this season (10-21). Furthermore, their performance in this spot has deteriorated recently, as they have won just 25.0% of underdog matchups over their last 10 contests.

• Total Pick: Under 8.5 runs (-110 at BetMGM)

Despite the offensive mismatch, my secondary play targets the Under 8.5 runs. Both starting pitchers boast sub-2.00 ERAs. Additionally, the Under has cashed at a 70.0% clip over the last 10 games for both clubs. The math heavily supports a low-scoring affair.

• Player Prop Picks: José Soriano over 5.5 strikeouts (-130 at Bet365)

For player props, I am looking at José Soriano OVER 5.5 Pitcher Strikeouts (-130 at Bet365). Soriano is missing bats at an elite clip with a 10.10 K/9 rate. Assuming he completes his season average of six innings per start, he should clear this number against any lineup.

Odds as of May 16, 2026, at 1:09 PM ET from BetMGM, Bet365, and Caesars Sportsbook

Justin Wrobleski vs José Soriano

The pitching matchup features two arms dominating the 2026 campaign. Both starters rely on distinctly different profiles to record outs.

Justin Wrobleski commands the strike zone and induces weak contact to maneuver through at-bats. The southpaw logs just 4.43 strikeouts per nine innings but limits opposing hitters to a .196 batting average. His 0.96 WHIP keeps the basepaths clear, helping him average nearly seven innings per appearance. You can see how these pitchers fare against their opponents on our MLB batter vs pitcher stats page.

José Soriano attacks with pure swing-and-miss stuff. His 1.66 ERA and 3.16 FIP indicate sustainable dominance. Striking out 10.10 batters per nine innings, he effectively erases base runners despite a slightly elevated 3.31 BB/9 rate.

Team Statistical Comparison

Diving into the underlying metrics reveals a one-sided affair. I focus on road statistics for the visitors and home statistics for the hosts to highlight the situational gap.

The visitors are an elite offensive unit away from Chavez Ravine, leading baseball in road batting average and OPS. They plate nearly six runs per game. Conversely, Anaheim ranks dead last in MLB in home batting average and OPS, generating just 3.21 runs per game at Angel Stadium. You can check out our MLB park factors page to see how this stadium could impact this game.

The mismatch extends to the mound. The visiting bullpen and rotation combine for a league-best 1.11 WHIP, neutralizing rallies quickly. Anaheim’s staff constantly works itself out of trouble with a bloated 1.43 WHIP.

Dodgers vs Angels Odds

Odds as of May 16, 2026, at 1:01 PM ET from BetMGM, Caesars Sportsbook, and DraftKings

MLB odds establish the visiting squad as decisive -140 moneyline favorites. Early action heavily backed the formidable road team, pushing the line from the opening marks of -135 for the favorites and +118 for the underdogs.

On the runline, you can lay 1.5 runs with the favorites at +119, which has tightened slightly from an opening price of +122. The game total remains firmly set at 8.5 with standard -110 juice on both sides, showing no movement from the opening number despite early action on the Over.

Public Betting Splits

When analyzing the MLB public betting percentages for this crosstown rivalry, the ticket and money percentages reveal heavy alignment on the moneyline. The road favorites command 85% of the moneyline tickets and an 54% of the total handle.

With a clear talent discrepancy, the financial backing rightfully aligns with the better roster.

The total runs market tells a slightly different story regarding my projections. Currently, 44% of the tickets and 41% of the money are riding on the Over. While the public and the money align on a high-scoring game, my analysis leans contrarian. Given the elite run-prevention profiles of both starters, I trust the Under.

Dodgers vs Angels Injury Report

Both clubs are navigating significant health issues impacting their daily game plans.

The visitors are dealing with multiple injuries to high-leverage pitchers like Tyler Glasnow and Edwin Díaz. However, their unparalleled organizational depth has allowed them to continue firing on all cylinders, largely masking these absences for moneyline bettors.

Conversely, Anaheim’s injuries severely limit their tactical options. Missing catchers Logan O’Hoppe and Travis d’Arnaud create a glaring void behind the plate, offering opposing runners a green light to steal bases. This lack of healthy, productive bats strongly reinforces my betting angle that supports a low-scoring Under.